CTBP1 (C-terminal binding protein 1) - Rat Genome Database

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Gene: CTBP1 (C-terminal binding protein 1) Pan paniscus
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Symbol: CTBP1
Name: C-terminal binding protein 1
RGD ID: 11791927
Description: ENCODES a protein that exhibits chromatin binding (ortholog); lncRNA binding (ortholog); PDZ domain binding (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); Notch signaling pathway (ortholog); presynapse to nucleus signaling pathway (ortholog); PARTICIPATES IN Notch signaling pathway; ASSOCIATED WITH cherubism (ortholog); Colorectal Neoplasms (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (ortholog); extrinsic component of presynaptic endocytic zone membrane (ortholog); GABA-ergic synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: C-terminal-binding protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v231,542,985 - 1,581,765 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan141,509,137 - 1,547,666 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v041,354,806 - 1,393,244 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.141,238,982 - 1,275,536 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl41,238,984 - 1,266,822 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CTBP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v231,542,985 - 1,581,765 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan141,509,137 - 1,547,666 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v041,354,806 - 1,393,244 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.141,238,982 - 1,275,536 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl41,238,984 - 1,266,822 (-)Ensemblpanpan1.1panPan2
CTBP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3841,211,445 - 1,250,355 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl41,211,445 - 1,250,333 (-)EnsemblGRCh38hg38GRCh38
GRCh3741,205,233 - 1,244,143 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3641,195,228 - 1,232,908 (-)NCBINCBI36Build 36hg18NCBI36
Build 3441,195,117 - 1,232,621NCBI
Celera41,138,238 - 1,175,924 (-)NCBICelera
Cytogenetic Map4p16.3NCBI
HuRef41,173,813 - 1,211,667 (-)NCBIHuRef
CHM1_141,204,881 - 1,242,708 (-)NCBICHM1_1
T2T-CHM13v2.041,210,608 - 1,249,282 (-)NCBIT2T-CHM13v2.0
Ctbp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39533,405,067 - 33,432,348 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl533,405,067 - 33,432,338 (-)EnsemblGRCm39 Ensembl
GRCm38533,247,723 - 33,275,004 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl533,247,723 - 33,274,994 (-)EnsemblGRCm38mm10GRCm38
MGSCv37533,590,372 - 33,617,618 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36533,564,580 - 33,591,826 (-)NCBIMGSCv36mm8
Celera530,726,910 - 30,746,219 (-)NCBICelera
Cytogenetic Map5B1NCBI
cM Map517.52NCBI
Ctbp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81481,679,956 - 81,707,331 (+)NCBIGRCr8
mRatBN7.21477,455,580 - 77,482,821 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1477,455,696 - 77,482,821 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1481,897,623 - 81,924,823 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01483,138,172 - 83,165,372 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01479,583,490 - 79,610,690 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01482,762,109 - 82,789,350 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1482,762,190 - 82,789,319 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01483,447,911 - 83,475,152 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41483,022,824 - 83,050,335 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11483,025,214 - 83,052,726 (-)NCBI
Celera1476,376,169 - 76,398,029 (+)NCBICelera
Cytogenetic Map14q21NCBI
Ctbp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955514626,645 - 652,817 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955514630,168 - 652,817 (-)NCBIChiLan1.0ChiLan1.0
CTBP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1391,385,733 - 91,400,252 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl391,379,049 - 91,400,656 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha393,843,707 - 93,867,009 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0392,375,018 - 92,398,321 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl392,374,989 - 92,398,326 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1391,548,411 - 91,571,713 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0391,601,300 - 91,624,692 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0391,985,325 - 92,008,625 (+)NCBIUU_Cfam_GSD_1.0
Ctbp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528568,331,034 - 68,353,468 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647722,032,664 - 22,055,187 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647722,032,712 - 22,055,160 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CTBP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8475,888 - 496,002 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18475,164 - 496,510 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CTBP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12747,533,490 - 47,570,505 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2747,544,682 - 47,570,636 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660513,909,688 - 3,946,439 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ctbp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475525,999,713 - 26,021,331 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475525,998,524 - 26,021,223 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000042236   ⟹   ENSPPAP00000019471
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl41,238,984 - 1,264,101 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000042241   ⟹   ENSPPAP00000019476
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl41,239,781 - 1,266,822 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000042249   ⟹   ENSPPAP00000019482
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl41,240,475 - 1,264,095 (-)Ensembl
RefSeq Acc Id: XM_008963691   ⟹   XP_008961939
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v231,542,985 - 1,575,796 (-)NCBI
NHGRI_mPanPan141,509,137 - 1,541,862 (-)NCBI
Mhudiblu_PPA_v041,354,806 - 1,387,596 (-)NCBI
PanPan1.141,238,982 - 1,273,662 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034958155   ⟹   XP_034814046
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v231,542,985 - 1,580,547 (-)NCBI
NHGRI_mPanPan141,509,137 - 1,546,582 (-)NCBI
Mhudiblu_PPA_v041,354,806 - 1,392,367 (-)NCBI
RefSeq Acc Id: XM_034958156   ⟹   XP_034814047
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v231,542,985 - 1,580,547 (-)NCBI
NHGRI_mPanPan141,509,137 - 1,546,582 (-)NCBI
Mhudiblu_PPA_v041,354,806 - 1,392,367 (-)NCBI
RefSeq Acc Id: XM_034958157   ⟹   XP_034814048
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v231,542,985 - 1,580,485 (-)NCBI
NHGRI_mPanPan141,509,137 - 1,546,587 (-)NCBI
Mhudiblu_PPA_v041,354,806 - 1,392,373 (-)NCBI
RefSeq Acc Id: XM_034958158   ⟹   XP_034814049
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v231,542,985 - 1,580,175 (-)NCBI
NHGRI_mPanPan141,509,137 - 1,546,284 (-)NCBI
Mhudiblu_PPA_v041,354,806 - 1,392,002 (-)NCBI
RefSeq Acc Id: XM_034958159   ⟹   XP_034814050
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v231,542,985 - 1,580,484 (-)NCBI
NHGRI_mPanPan141,509,137 - 1,546,587 (-)NCBI
Mhudiblu_PPA_v041,354,806 - 1,392,373 (-)NCBI
RefSeq Acc Id: XM_034958161   ⟹   XP_034814052
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v231,542,985 - 1,580,182 (-)NCBI
NHGRI_mPanPan141,509,137 - 1,546,299 (-)NCBI
Mhudiblu_PPA_v041,354,806 - 1,391,993 (-)NCBI
RefSeq Acc Id: XM_034958162   ⟹   XP_034814053
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v231,542,985 - 1,581,515 (-)NCBI
NHGRI_mPanPan141,509,137 - 1,547,540 (-)NCBI
Mhudiblu_PPA_v041,354,806 - 1,393,244 (-)NCBI
RefSeq Acc Id: XM_055111113   ⟹   XP_054967088
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v231,542,985 - 1,579,784 (-)NCBI
NHGRI_mPanPan141,509,137 - 1,544,085 (-)NCBI
RefSeq Acc Id: XM_055111115   ⟹   XP_054967090
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v231,542,985 - 1,581,765 (-)NCBI
NHGRI_mPanPan141,509,137 - 1,547,666 (-)NCBI
RefSeq Acc Id: XM_055111116   ⟹   XP_054967091
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v231,542,985 - 1,579,788 (-)NCBI
NHGRI_mPanPan141,509,137 - 1,545,881 (-)NCBI
RefSeq Acc Id: XM_057302017   ⟹   XP_057158000
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v231,542,985 - 1,581,500 (-)NCBI
NHGRI_mPanPan141,509,137 - 1,547,540 (-)NCBI
RefSeq Acc Id: XM_063603663   ⟹   XP_063459733
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v231,542,985 - 1,581,510 (-)NCBI
RefSeq Acc Id: XP_008961939   ⟸   XM_008963691
- Peptide Label: isoform X3
- UniProtKB: A0A2R9AQ23 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034814053   ⟸   XM_034958162
- Peptide Label: isoform X4
- UniProtKB: A0A2R9AQ28 (UniProtKB/TrEMBL),   A0A2R9AQ23 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034814050   ⟸   XM_034958159
- Peptide Label: isoform X4
- UniProtKB: A0A2R9AQ28 (UniProtKB/TrEMBL),   A0A2R9AQ23 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034814048   ⟸   XM_034958157
- Peptide Label: isoform X3
- UniProtKB: A0A2R9AQ23 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034814047   ⟸   XM_034958156
- Peptide Label: isoform X2
- UniProtKB: A0A2R9AQ23 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034814046   ⟸   XM_034958155
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AQ23 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034814049   ⟸   XM_034958158
- Peptide Label: isoform X3
- UniProtKB: A0A2R9AQ23 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034814052   ⟸   XM_034958161
- Peptide Label: isoform X4
- UniProtKB: A0A2R9AQ28 (UniProtKB/TrEMBL),   A0A2R9AQ23 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSPPAP00000019471   ⟸   ENSPPAT00000042236
Ensembl Acc Id: ENSPPAP00000019482   ⟸   ENSPPAT00000042249
Ensembl Acc Id: ENSPPAP00000019476   ⟸   ENSPPAT00000042241
RefSeq Acc Id: XP_054967090   ⟸   XM_055111115
- Peptide Label: isoform X4
- UniProtKB: A0A2R9AQ28 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054967091   ⟸   XM_055111116
- Peptide Label: isoform X4
- UniProtKB: A0A2R9AQ28 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054967088   ⟸   XM_055111113
- Peptide Label: isoform X4
- UniProtKB: A0A2R9AQ28 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_057158000   ⟸   XM_057302017
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063459733   ⟸   XM_063603663
- Peptide Label: isoform X3
Protein Domains
D-isomer specific 2-hydroxyacid dehydrogenase   D-isomer specific 2-hydroxyacid dehydrogenase NAD-


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000032870 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000042236.1 UniProtKB/TrEMBL
  ENSPPAT00000042241.1 UniProtKB/TrEMBL
  ENSPPAT00000042249.1 UniProtKB/TrEMBL
Gene3D-CATH NAD(P)-binding Rossmann-like Domain UniProtKB/TrEMBL
InterPro CtBP UniProtKB/TrEMBL
  CTBP_dehydrogenase UniProtKB/TrEMBL
  D-isomer_2_OHA_DH_cat_dom UniProtKB/TrEMBL
  D-isomer_DH_CS UniProtKB/TrEMBL
  D-isomer_DH_CS1 UniProtKB/TrEMBL
  D-isomer_DH_NAD-bd UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/TrEMBL
NCBI Gene CTBP1 ENTREZGENE
PANTHER C-TERMINAL-BINDING PROTEIN UniProtKB/TrEMBL
  C-TERMINAL-BINDING PROTEIN 1 UniProtKB/TrEMBL
Pfam 2-Hacid_dh UniProtKB/TrEMBL
  2-Hacid_dh_C UniProtKB/TrEMBL
PROSITE D_2_HYDROXYACID_DH_1 UniProtKB/TrEMBL
  D_2_HYDROXYACID_DH_3 UniProtKB/TrEMBL
Superfamily-SCOP Formate/glycerate dehydrogenase catalytic domain-like UniProtKB/TrEMBL
  SSF51735 UniProtKB/TrEMBL
UniProt A0A2R9AQ23 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AQ28 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AQ44_PANPA UniProtKB/TrEMBL