| 2592 | Fabp6 | fatty acid binding protein 6 | ENCODES a protein that exhibits fatty acid binding; INVOLVED IN steroid metabolic process; PARTICIPATES IN eicosanoid signaling pathway via peroxisome proliferator-activated receptor gamma; FOUND IN cytoplasm (inferred); membrane (inferred); INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)eth ane; ammonium chloride; bisphenol A | 10 | 28565054 | 28569727 | Rat | 94 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308066 | Shroom1 | shroom family member 1 | ENCODES a protein that exhibits actin filament binding (ortholog); myosin II binding (ortholog); INVOLVED IN actin filament bundle assembly (ortholog); cell morphogenesis (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN cytoskeleton (inferred); microtubule (inferred); INTERACTS WITH 17beta- estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 10 | 38121971 | 38134832 | Rat | 85 | symbol , PhenoGen , name | gene, protein-coding, MODEL [RefSeq] |
| 1565163 | Shroom2 | shroom family member 2 | ENCODES a protein that exhibits actin binding (ortholog); actin filament binding (ortholog); beta-catenin binding (ortholog); INVOLVED IN actin filament bundle assembly (ortholog); cell migration (ortholog); cell morphogenesis (ortholog); ASSOCIATED WITH Meniere's disease (ortholog); FOUND IN adhere ns junction (ortholog); apical junction complex (ortholog); apical plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 3,3',4,4',5-pentachlorobiphenyl | X | 25308163 | 25480194 | Rat | 127 | symbol , PhenoGen , name | gene, protein-coding, VALIDATED [RefSeq] |
| 1310470 | Shroom3 | shroom family member 3 | ENCODES a protein that exhibits actin binding (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); columnar/cuboidal epithelial cell development (ortholog); neural tube closure (ortholog); ASSOCIATED WITH tetralogy of Fallot (ortholog); FOUND IN adherens junction (ortholog); apical ju nction complex (ortholog); apical part of cell (ortholog); INTERACTS WITH 17beta-estradiol; 6-propyl-2-thiouracil; bisphenol A | 14 | 15383769 | 15681158 | Rat | 117 | symbol , old_gene_name , PhenoGen , name , old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1563434 | Shroom4 | shroom family member 4 | ENCODES a protein that exhibits actin filament binding (ortholog); myosin II binding (ortholog); INVOLVED IN regulation of postsynaptic membrane neurotransmitter receptor levels; actin filament organization (ortholog); brain development (ortholog); ASSOCIATED WITH intellectual disability (ortholog); Stocco Dos Santos type X-linked intellectual disability (ortholog); FOUND IN GABA-ergic synapse; glutamatergic synapse; postsynapse; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 3,3',4,4',5-pentachlorobiphenyl | X | 18537371 | 18748665 | Rat | 93 | symbol , PhenoGen , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 14394503 | Klrb1aem1Mcwi | killer cell lectin-like receptor subfamily B, member 1A; CRISPR/Cas9 induced mutant 1, Mcwi | CRISPR/Cas9 system was used to introduce a 5-bp deletion in exon 2 in SHR/NCrl embryos. | | | | Rat | | description | gene, allele |
| 14394505 | Klrb1aem2Mcwi | killer cell lectin-like receptor subfamily B, member 1A; CRISPR/Cas9 induced mutant 2, Mcwi | CRISPR/Cas9 system was used to introduce a 102-bp deletion in exon 2 in SHR/NCrl embryos. | | | | Rat | | description | gene, allele |
| 149735372 | C3em1Kyo | complement C3; ZFN induced mutant 1, Kyo | ZFN constructs specific for the rat C3 gene were designed to target bases 1803-1841 (NCBI reference sequence: NM_016994) of C3 (target sequence: cagggggcccgagtgggctagtggctgtggacaagggg) by Sigma-Aldrich (Tokyo, Japan). The ZFN systems were injected into the pronucleus of SHR '>SHR/Izm embryos. The pups were identified by primers flanking the target sequence (forward primer: 5'-ACTCTTCCCTGTCTTGCGTC-3'; reverse primer: 5'--AATAGAGGCCACCAATGCAC-3'). This mutant allele revealed a 9-base frameshift deletion of bases 1815-1824 (ggctagtgg). | | | | Rat | | description | gene, allele |
| 19259465 | Camk2n1em1Tja | calcium/calmodulin-dependent protein kinase II inhibitor 1; ZFN induced mutant 1, Tja | INVOLVED IN positive regulation of insulin secretion involved in cellular response to glucose stimulus; positive regulation of systemic arterial blood pressure; ASSOCIATED WITH decreased brown adipose tissue mass; decreased epididymal fat pad weight; decreased heart left ventricle weight | | | | Rat | 9 | description | gene, allele |
| 127285405 | Cfbem1Tja | complement factor B, ZFN induced mutant 1, Tja | ASSOCIATED WITH decreased brown adipose tissue amount; decreased circulating aldosterone level; decreased circulating cholesterol level | | | | Rat | 13 | description | gene, allele |
| 12791992 | Gja8m1Cub | gap junction protein, alpha 8; mutant 1 Cub | ASSOCIATED WITH abnormal lens capsule morphology; abnormal lens development; abnormal lens epithelium morphology; ASSOCIATED WITH cataract; cataract 1 multiple types; microphthalmia | | | | Rat | 34 | description | gene, allele |
| 10002755 | Sbf1m1Ipcv | SET binding factor 1; mutation 1, Institute of Physiology, Czechoslovac Academy of Sciences | ASSOCIATED WITH arrest of spermiogenesis; azoospermia; decreased testis weight | | | | Rat | 4 | description | gene, allele |
| 150340624 | Zbtb16em1Ipcv | zinc finger and BTB domain containing 16; TALEN induced mutant 1, Ipcv | ASSOCIATED WITH cardiac interstitial fibrosis; decreased body weight; decreased circulating cholesterol level | | | | Rat | 10 | description | gene, allele |
| 12910834 | Zbtb16Lx | zinc finger and BTB domain containing 16, Lx mutant | ASSOCIATED WITH preaxial polydactyly; ASSOCIATED WITH polydactyly | | | | Rat | 2 | description | gene, allele |
| 1590138 | Ajap1 | adherens junctions associated protein 1 | ENCODES a protein that exhibits beta-catenin binding (ortholog); protein domain specific binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN negative regulation of cell-matrix adhesion (ortholog); negative regulation of wound healing (ortholog); regulation of polarized epi thelial cell differentiation (ortholog); ASSOCIATED WITH Neurodevelopmental Disorders (ortholog); FOUND IN adherens junction (ortholog); basolateral plasma membrane (ortholog); cell surface (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 5 | 169190477 | 169302938 | Rat | 89 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 13792814 | Spp1em2Mcwi | secreted phosphoprotein 1; CRISPR/Cas9 induced mutant 2, Mcwi | CRISPR/Cas9 system was used to introduce a mutation in the Spp1 gene of SHRSP/A3NCrl rat embryos. The resulting mutation is a 11-bp deletion in Exon 3 of the Spp1 gene. | | | | Rat | | description | gene, allele |