Wnt1 Gene Search Result

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14 records found for search term Wnt1

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
11491	Wnt1	wingless-type MMTV integration site family, member 1	Enables cytokine activity and protein domain specific binding activity. Involved in several processes, including astrocyte-dopaminergic neuron signaling; central nervous system development; and embryonic brain development. Acts upstream of or within several processes, including hemopoiesis; nervous ... (more) system development; and regulation of protein metabolic process. Located in cell surface and extracellular region. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; embryo ectoderm; and genitourinary system. Used to study breast cancer. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 15. Orthologous to human WNT1 (Wnt family member 1). [provided by Alliance of Genome Resources, Jul 2025]	15	98687738	98691711	Mouse	341	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
1312745	Wnt10b	wingless-type MMTV integration site family, member 10B	Predicted to enable cytokine activity and frizzled binding activity. Involved in negative regulation of cold-induced thermogenesis. Acts upstream of or within several processes, including cell surface receptor signaling pathway; positive regulation of cell differentiation; and regulation of DNA-temp ... (more) lated transcription. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including genitourinary system; integumental system; jaw; nervous system; and surface ectoderm. Human ortholog(s) of this gene implicated in obesity; split hand-foot malformation 6; and tooth agenesis. Orthologous to human WNT10B (Wnt family member 10B). [provided by Alliance of Genome Resources, Jul 2025]	15	98668593	98676093	Mouse	188	symbol , PhenoGen , description , old_gene_symbol	gene, protein-coding, VALIDATED [RefSeq]
733304	Wnt2b	wingless-type MMTV integration site family, member 2B	Predicted to enable cytokine activity and frizzled binding activity. Involved in forebrain regionalization. Acts upstream of or within several processes, including canonical Wnt signaling pathway; mesenchymal-epithelial cell signaling; and regulation of morphogenesis of a branching structure. Predic ... (more) ted to be located in intracellular membrane-bounded organelle. Predicted to be active in extracellular space. Is expressed in several structures, including alimentary system; brain; reproductive system; sensory organ; and urethra. Human ortholog(s) of this gene implicated in congenital diarrhea. Orthologous to human WNT2B (Wnt family member 2B). [provided by Alliance of Genome Resources, Apr 2025]	3	104852121	104869025	Mouse	147	old_gene_symbol	gene, protein-coding, PROVISIONAL [RefSeq]
1312798	Wnt9a	wingless-type MMTV integration site family, member 9A	Predicted to enable cytokine activity and frizzled binding activity. Acts upstream of or within several processes, including embryonic morphogenesis; negative regulation of chondrocyte differentiation; and positive regulation of smoothened signaling pathway. Predicted to be located in extracellular ... (more) region. Predicted to be active in extracellular space. Is expressed in several structures, including brain; craniocervical region bone; limb; reproductive system; and urethra. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human WNT9A (Wnt family member 9A). [provided by Alliance of Genome Resources, Jul 2025]	11	59197675	59224378	Mouse	143	old_gene_symbol	gene, protein-coding, VALIDATED [RefSeq]
1319984	Wnt9b	wingless-type MMTV integration site family, member 9B	Enables co-receptor binding activity and signaling receptor binding activity. Acts upstream of or within several processes, including Wnt signaling pathway; chordate embryonic development; and kidney development. Predicted to be located in extracellular region. Predicted to be part of Wnt-Frizzled-L ... (more) RP5/6 complex. Predicted to be active in extracellular space. Is expressed in several structures, including central nervous system; epithelium; genitourinary system; heart; and surface ectoderm. Orthologous to human WNT9B (Wnt family member 9B). [provided by Alliance of Genome Resources, Jul 2025]	11	103618188	103666098	Mouse	140	old_gene_symbol	gene, protein-coding, VALIDATED [RefSeq]
1551747	H2az2	H2A.Z histone variant 2	Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin ... (more) fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. [provided by RefSeq, Nov 2015]	11	6377226	6394511	Mouse	1602	old_gene_symbol	gene, protein-coding, REVIEWED [RefSeq]
730924	E2f1	E2F transcription factor 1	Enables DNA-binding transcription activator activity and transcription cis-regulatory region binding activity. Involved in several processes, including negative regulation of fat cell differentiation; negative regulation of fat cell proliferation; and response to lipopolysaccharide. Acts upstream of ... (more) or within several processes, including anoikis; lens fiber cell apoptotic process; and quinolinate biosynthetic process. Located in chromatin and cytoplasm. Part of transcription regulator complex. Is active in nucleus. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and lung. Used to study Sjogren's syndrome and type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in lung carcinoma (multiple); osteosarcoma; and pancreatic adenocarcinoma (multiple). Orthologous to human E2F1 (E2F transcription factor 1). [provided by Alliance of Genome Resources, Apr 2025]	2	154401320	154411812	Mouse	905	old_gene_symbol	gene, protein-coding, VALIDATED [RefSeq]
1619149	Rhou	ras homolog family member U	Enables GTPase activity. Acts upstream of or within several processes, including G1/S transition of mitotic cell cycle; Rac protein signal transduction; and regulation of cell shape. Predicted to be located in several cellular components, including Golgi membrane; focal adhesion; and podosome. Predi ... (more) cted to be active in plasma membrane. Is expressed in several structures, including branchial pouch; cerebral cortex; ganglia; gut; and hair follicle. Orthologous to human RHOU (ras homolog family member U). [provided by Alliance of Genome Resources, Apr 2025]	8	124380609	124390622	Mouse	173	old_gene_name	gene, protein-coding, VALIDATED [RefSeq]
69488	Ccn4	cellular communication network factor 4	Predicted to enable heparin binding activity and integrin binding activity. Involved in several processes, including negative regulation of cell differentiation; osteoblast differentiation; and osteoclast differentiation. Located in cytoplasm. Is expressed in several structures, including central ne ... (more) rvous system; embryo mesenchyme; genitourinary system; limb; and skeleton. Orthologous to human CCN4 (cellular communication network factor 4). [provided by Alliance of Genome Resources, Jul 2025]	15	66763337	66795050	Mouse	164	old_gene_name	gene, protein-coding, VALIDATED [RefSeq]
737121	Ccn5	cellular communication network factor 5	Predicted to enable growth factor activity; heparin binding activity; and integrin binding activity. Acts upstream of or within regulation of cell growth. Located in extracellular space; nucleus; and plasma membrane. Is expressed in several structures, including cardiovascular system; genitourinary ... (more) system; gut; long bone epiphyseal plate; and respiratory system. Orthologous to human CCN5 (cellular communication network factor 5). [provided by Alliance of Genome Resources, Jul 2025]	2	163662724	163675066	Mouse	177	old_gene_name	gene, protein-coding, VALIDATED [RefSeq]
1622848	Ccn6	cellular communication network factor 6	Predicted to enable heparin binding activity and integrin binding activity. Predicted to be involved in several processes, including positive regulation of cell differentiation; regulation of mitochondrial membrane potential; and regulation of reactive oxygen species biosynthetic process. Predicted ... (more) to act upstream of or within negative regulation of angiogenesis and negative regulation of cell population proliferation. Predicted to be located in mitochondrion. Predicted to be active in extracellular matrix and extracellular space. Is expressed in embryo. Used to study breast metaplastic carcinoma and progressive pseudorheumatoid arthropathy of childhood. Human ortholog(s) of this gene implicated in arthropathy and progressive pseudorheumatoid arthropathy of childhood. Orthologous to human CCN6 (cellular communication network factor 6). [provided by Alliance of Genome Resources, Jul 2025]	10	39026966	39049484	Mouse	81	old_gene_name	gene, protein-coding, VALIDATED [RefSeq]
1551956	Wnt11	wingless-type MMTV integration site family, member 11	Predicted to enable enzyme activator activity and signaling receptor binding activity. Involved in heart development. Acts upstream of or within several processes, including Wnt signaling pathway; circulatory system development; and negative regulation of cell population proliferation. Located in ex ... (more) tracellular matrix and extracellular region. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and limb. Human ortholog(s) of this gene implicated in oral squamous cell carcinoma. Orthologous to human WNT11 (Wnt family member 11). [provided by Alliance of Genome Resources, Apr 2025]	7	98484293	98503954	Mouse	221	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
1558269	Wnt16	wingless-type MMTV integration site family, member 16	Predicted to enable cytokine activity and frizzled binding activity. Acts upstream of or within bone remodeling and cardiac epithelial to mesenchymal transition. Predicted to be located in cytoplasm. Predicted to be active in extracellular space. Is expressed in several structures, including aliment ... (more) ary system; brain; embryo mesenchyme; genitourinary system; and heart. Orthologous to human WNT16 (Wnt family member 16). [provided by Alliance of Genome Resources, Jul 2025]	6	22288179	22298521	Mouse	99	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
1315959	Wnt10a	wingless-type MMTV integration site family, member 10A	Predicted to enable cytokine activity and frizzled binding activity. Acts upstream of or within neural crest cell differentiation; positive regulation of gene expression; and regulation of odontogenesis of dentin-containing tooth. Predicted to be located in extracellular region. Predicted to be acti ... (more) ve in extracellular space. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in Schopf-Schulz-Passarge syndrome; ectodermal dysplasia; and tooth agenesis. Orthologous to human WNT10A (Wnt family member 10A). [provided by Alliance of Genome Resources, Jul 2025]	1	74831178	74843335	Mouse	178	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]