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Pathways
Genes search result for Mus musculus
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10 records found for search term Ufm1
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
1550713Ufm1ubiquitin-fold modifier 1Involved in protein ufmylation and response to endoplasmic reticulum stress. Located in endoplasmic reticulum and nucleus. Is expressed in embryo and pancreas epithelium. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 14. Orthologous to human UFM135376079753771228Mouse143symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
1319588Ufl1UFM1 specific ligase 1Predicted to enable UFM1 ligase activity and protein kinase binding activity. Involved in several processes, including hemopoiesis; negative regulation of T cell activation; and positive regulation of autophagy. Acts upstream of or within positive regulation of 42524714925281821Mouse211old_gene_name , name , descriptiongene, protein-coding, VALIDATED [RefSeq]
1623958Ufsp1UFM1-specific peptidase 1Enables deUFMylase activity. Predicted to be involved in protein maturation. Predicted to be active in cytosol. Is expressed in several structures, including diaphragm; limb segment; nervous system; skeletal musculature; and thymus primordium. Orthologous to human UFSP1 (UFM15137292931137293926Mouse53old_gene_name , name , descriptiongene, protein-coding, VALIDATED [RefSeq]
1322473Ufsp2UFM1-specific peptidase 2Enables deUFMylase activity. Involved in regulation of type II interferon production. Located in endoplasmic reticulum and nucleus. Is expressed in liver; orbito-sphenoid; pancreas epithelium; and turbinate bone primordium. Human ortholog(s) of this gene implicated in Beukes hip dysplasia and develo84642855146449995Mouse98old_gene_name , name , descriptiongene, protein-coding, VALIDATED [RefSeq]
1323297Uba5ubiquitin-like modifier activating enzyme 5Enables UFM1 activating enzyme activity. Involved in myeloid cell differentiation; protein ufmylation; and regulation of type II interferon production. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in cytosol. Is expressed in 9103923786103940767Mouse160old_gene_name , descriptiongene, protein-coding, VALIDATED [RefSeq]
1615128Ufc1ubiquitin-fold modifier conjugating enzyme 1Enables UFM1 conjugating enzyme activity. Involved in protein ufmylation and regulation of type II interferon production. Is expressed in chondrocranium and liver. Human ortholog(s) of this gene implicated in neurodevelopmental disorder with spasticity and poor 1171116137171122575Mouse77old_gene_name , descriptiongene, protein-coding, VALIDATED [RefSeq]
1557559Ddrgk1DDRGK domain containing 1Predicted to enable RNA polymerase II-specific DNA-binding transcription factor binding activity; UFM1-modified protein reader activity; and ubiquitin-like protein ligase binding activity. Involved in several processes, including negative regulation of endoplasm2130495955130506549Mouse166old_gene_name , descriptiongene, protein-coding, VALIDATED [RefSeq]
1316998Zup1zinc finger containing ubiquitin peptidase 1Predicted to enable cysteine-type deubiquitinase activity and zinc ion binding activity. Predicted to be located in cytosol and nucleoplasm. Is expressed in early conceptus; inner cell mass; and oocyte. Orthologous to human ZUP1 (zinc finger containing ubiquitin peptidase 1). [provided by Alliance o103379513833827316Mouse79old_gene_namegene, protein-coding, VALIDATED [RefSeq]
1614357Saysd1SAYSVFN motif domain containing 1Predicted to enable UFM1-modified protein reader activity. Predicted to be involved in protein quality control for misfolded or incompletely synthesized proteins and rescue of stalled ribosome. Is active in endoplasmic reticulum. Orthologous to human SAYSD1 (SAY142012570420133240Mouse55descriptiongene, protein-coding, VALIDATED [RefSeq]
1319807Stk38serine/threonine kinase 38Predicted to enable several functions, including ATP binding activity; UFM1-modified protein reader activity; and magnesium ion binding activity. Predicted to be involved in several processes, including DNA damage checkpoint signaling; negative regulation of MAP172918985429226979Mouse194descriptiongene, protein-coding, VALIDATED [RefSeq]