Enables SNAP receptor activity and syntaxin-1 binding activity. Involved in presynaptic dense core vesicle exocytosis and regulation of neuron projection development. Acts upstream of or within several processes, including associative learning; long-term synaptic potentiation; and neurotransmitter s
ecretion. Located in several cellular components, including presynaptic membrane; synaptic vesicle; and trans-Golgi network. Part of synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex. Is active in glutamatergic synapse. Is expressed in adrenal gland; jaw; nervous system; and sensory organ. Used to study attention deficit hyperactivity disorder; obesity; schizophrenia; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in Down syndrome and congenital myasthenic syndrome 18. Orthologous to human SNAP25 (synaptosome associated protein 25). [provided by Alliance of Genome Resources, Apr 2025]
Predicted to enable protein-macromolecule adaptor activity. Involved in mitophagy and sensory perception of pain. Located in membrane and mitochondrion. Is active in synaptic membrane. Is expressed in several structures, including gonad; gut; nervous system; submandibular gland primordium; and tooth
Predicted to enable SNARE binding activity. Involved in anterograde synaptic vesicle transport; negative regulation of neuron projection development; and regulation of synaptic vesicle exocytosis. Acts upstream of or within several processes, including lysosomal lumen acidification; terminal button
organization; and vesicle organization. Located in acrosomal vesicle; cytosol; and manchette. Part of BLOC-1 complex. Is active in microvesicle. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and integumental system. Orthologous to human SNAPIN (SNAP associated protein). [provided by Alliance of Genome Resources, Jul 2025]