Scrib Gene Search Result

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Genes search result for Mus musculus
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4 records found for search term Scrib

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1321472	Scrib	scribbled planar cell polarity	Predicted to enable protein kinase binding activity and signaling adaptor activity. Involved in several processes, including establishment of T cell polarity; negative regulation of activated T cell proliferation; and synaptic vesicle cycle. Acts upstream of or within several processes, including ne ... (more) rvous system development; post-anal tail morphogenesis; and wound healing. Located in several cellular components, including basolateral plasma membrane; immunological synapse; and myelin sheath abaxonal region. Is expressed in several structures, including embryo mesenchyme; epithelium; metanephros; nervous system; and skin. Used to study prostate cancer. Orthologous to human SCRIB (scribble planar cell polarity protein). [provided by Alliance of Genome Resources, Jul 2025]	15	75919011	75941633	Mouse	324	symbol , old_gene_name , PhenoGen , name , description , old_gene_symbol	gene, protein-coding, VALIDATED [RefSeq]
10166	Apc	APC, WNT signaling pathway regulator	Enables several functions, including beta-catenin binding activity; dynein complex binding activity; and enzyme binding activity. Involved in insulin receptor signaling pathway; positive regulation of cold-induced thermogenesis; and positive regulation of protein localization to centrosome. Acts ups ... (more) tream of or within several processes, including negative regulation of epithelial cell proliferation; regionalization; and regulation of apoptotic process. Located in several cellular components, including axonal growth cone; cell projection membrane; and microtubule cytoskeleton. Part of Scrib-APC-beta-catenin complex. Is active in glutamatergic synapse and postsynapse. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and peripheral nervous system ganglion. Used to study breast cancer; familial adenomatous polyposis; gastrointestinal system cancer (multiple); and reproductive organ cancer (multiple). Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); familial adenomatous polyposis 1; gastrointestinal system cancer (multiple); hereditary desmoid disease; and reproductive organ cancer (multiple). Orthologous to human APC (APC regulator of WNT signaling pathway). [provided by Alliance of Genome Resources, Jul 2025]	18	34353350	34455243	Mouse	1412	description	gene, protein-coding, VALIDATED [RefSeq]
733153	Llgl1	LLGL1 scribble cell polarity complex component	Predicted to enable GTPase activator activity; enzyme binding activity; and myosin II binding activity. Acts upstream of or within maintenance of apical/basal cell polarity. Located in several cellular components, including basolateral plasma membrane; cytoskeleton; and myelin sheath abaxonal region ... (more) . Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human LLGL1 (LLGL scribble cell polarity complex component 1). [provided by Alliance of Genome Resources, Jul 2025]	11	60590501	60605012	Mouse	113	name , description	gene, protein-coding, VALIDATED [RefSeq]
1557962	Llgl2	LLGL2 scribble cell polarity complex component	Predicted to enable GTPase activator activity; PDZ domain binding activity; and myosin II binding activity. Acts upstream of or within establishment or maintenance of polarity of embryonic epithelium; labyrinthine layer development; and post-embryonic development. Predicted to be located in cytosol ... (more) and intracellular membrane-bounded organelle. Predicted to be active in cortical actin cytoskeleton and plasma membrane. Is expressed in several structures, including cardiovascular system; endocrine gland; genitourinary system; gut; and nasal cavity epithelium. Orthologous to human LLGL2 (LLGL scribble cell polarity complex component 2). [provided by Alliance of Genome Resources, Apr 2025]	11	115714855	115746606	Mouse	140	old_gene_name , name , description	gene, protein-coding, VALIDATED [RefSeq]