Egr1 Gene Search Result

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7 records found for search term Egr1

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
737111	EGR1	early growth response 1	The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppressor ... (more) gene. [provided by RefSeq, Dec 2014]	5	138465479	138469303	Human	1139	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
1319240	TOE1	target of EGR1, exonuclease	Enables poly(A)-specific ribonuclease activity and snRNA binding activity. Involved in snRNA 3'-end processing. Located in Cajal body and cytoplasm. Implicated in pontocerebellar hypoplasia type 7. [provided by Alliance of Genome Resources, Jul 2025]	1	45340170	45343973	Human	162	old_gene_name , name	gene, protein-coding, VALIDATED [RefSeq]
16562095	AC105129.1	target of EGR1, member 1 (nuclear) (TOE1) pseudogene					Human		name	gene, processed_pseudogene
736700	NAB1	NGFI-A binding protein 1	Predicted to enable transcription coregulator activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to act upstream of or within endochondral ossification; nervous system development; and regulation of epidermis development. Predicted to be located in nucleoplasm ... (more) . Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jul 2025]	2	190648895	190692766	Human	113	old_gene_name	gene, protein-coding, VALIDATED [RefSeq]
1323313	NAB2	NGFI-A binding protein 2	This gene encodes a member of the family of NGFI-A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo- or hetero-multimerize with other EGR or NAB proteins through ... (more) a conserved N-terminal domain, and repress transcription through two partially redundant C-terminal domains. Transcriptional repression by the encoded protein is mediated in part by interactions with the nucleosome remodeling and deactylase (NuRD) complex. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]	12	57089114	57095476	Human	172	old_gene_name	gene, protein-coding, REVIEWED [RefSeq]
16554204	NAB1P1	NAB1 pseudogene 1		X	151226033	151227734	Human		old_gene_name	gene, pseudo, INFERRED [RefSeq]
736498	PTGER4	prostaglandin E receptor 4	The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (... (more) pan style='font-weight:700;'>EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses. [provided by RefSeq, Jul 2008]	5	40679915	40746800	Human	324	description	gene, protein-coding, REVIEWED [RefSeq]