| 1304559 | Wnt6 | Wnt family member 6 | ENCODES a protein that exhibits signaling receptor binding (inferred); INVOLVED IN axis specification (ortholog); branching involved in ureteric bud morphogenesis (ortholog); epithelial-mesenchymal cell signaling (ortholog); PARTICIPATES IN Wnt signaling pathway; Wnt signaling, canonical pathway; ba sal cell carcinoma pathway; ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); bladder exstrophy-epispadias-cloacal exstrophy complex (ortholog); Desbuquois dysplasia (ortholog); FOUND IN cell surface (ortholog); extracellular matrix (ortholog); INTERACTS WITH 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 9 | 83778552 | 83792186 | Rat | 130 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1312067 | WNT6 | Wnt family member 6 | The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The gene overexpression may play key roles in carcinogenesis. This gene and the WNT10A gene are clustered in the chromosome 2q35 region. The protein encoded by this gene is 97% identical to the mouse Wnt6 protein at the amino acid level. [provided by RefSeq, Jul 2008] | 2 | 218859805 | 218874233 | Human | 189 | symbol , COSMIC , description , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1312068 | Wnt6 | wingless-type MMTV integration site family, member 6 | Predicted to enable cytokine activity and frizzled binding activity. Acts upstream of or within several processes, including epithelial-mesenchymal cell signaling; nephron tubule morphogenesis; and positive regulation of macromolecule biosynthetic process. Located in cell surface and extracellular m atrix. Is expressed in several structures, including alimentary system; genitourinary system; limb; nervous system; and sensory organ. Orthologous to human WNT6 (Wnt family member 6). [provided by Alliance of Genome Resources, Jul 2025] | 1 | 74793499 | 74824481 | Mouse | 140 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8943156 | Wnt6 | Wnt family member 6 | INVOLVED IN axis specification (ortholog); branching involved in ureteric bud morphogenesis (ortholog); epithelial-mesenchymal cell signaling (ortholog); PARTICIPATES IN Wnt signaling pathway; Wnt signaling pathway; Wnt signaling, canonical pathway; ASSOCIATED WITH Animal Mammary Neoplasms (ortholog ); bladder exstrophy-epispadias-cloacal exstrophy complex (ortholog); Desbuquois dysplasia (ortholog); FOUND IN cell surface (ortholog); extracellular matrix (ortholog) | NW_004955453 | 14547427 | 14560001 | Chinchilla | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11899278 | WNT6 | Wnt family member 6 | ENCODES a protein that exhibits cytokine activity (inferred); frizzled binding (inferred); signaling receptor binding (inferred); INVOLVED IN axis specification (ortholog); branching involved in ureteric bud morphogenesis (ortholog); epithelial-mesenchymal cell signaling (ortholog); PARTICIPATES IN Wnt signaling pathway; Wnt signaling, canonical pathway; ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); bladder exstrophy-epispadias-cloacal exstrophy complex (ortholog); Desbuquois dysplasia (ortholog); FOUND IN cell surface (inferred); extracellular matrix (inferred); extracellular region (inferred) | 2B | 106119740 | 106134317 | Bonobo | 32 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12130407 | WNT6 | Wnt family member 6 | ENCODES a protein that exhibits signaling receptor binding (inferred); INVOLVED IN axis specification (ortholog); branching involved in ureteric bud morphogenesis (ortholog); epithelial-mesenchymal cell signaling (ortholog); PARTICIPATES IN Wnt signaling pathway; Wnt signaling pathway; Wnt signaling , canonical pathway; ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); bladder exstrophy-epispadias-cloacal exstrophy complex (ortholog); Desbuquois dysplasia (ortholog); FOUND IN cell surface (inferred); extracellular matrix (inferred); extracellular region (inferred) | 37 | 25452875 | 25457437 | Dog | 31 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12626366 | Wnt6 | Wnt family member 6 | ENCODES a protein that exhibits cytokine activity (inferred); frizzled binding (inferred); signaling receptor binding (inferred); INVOLVED IN axis specification (ortholog); branching involved in ureteric bud morphogenesis (ortholog); epithelial-mesenchymal cell signaling (ortholog); PARTICIPATES IN Wnt signaling pathway; Wnt signaling pathway; Wnt signaling, canonical pathway; ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); bladder exstrophy-epispadias-cloacal exstrophy complex (ortholog); Desbuquois dysplasia (ortholog); FOUND IN cell surface (inferred); extracellular matrix (inferred); extracellular region (inferred) | NW_004936569 | 1290061 | 1302672 | Squirrel | 31 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14115511 | WNT6 | Wnt family member 6 | ENCODES a protein that exhibits signaling receptor binding (inferred); INVOLVED IN axis specification (ortholog); branching involved in ureteric bud morphogenesis (ortholog); epithelial-mesenchymal cell signaling (ortholog); PARTICIPATES IN Wnt signaling pathway; Wnt signaling, canonical pathway; AS SOCIATED WITH Animal Mammary Neoplasms (ortholog); bladder exstrophy-epispadias-cloacal exstrophy complex (ortholog); Desbuquois dysplasia (ortholog); FOUND IN cell surface (inferred); extracellular matrix (inferred); extracellular region (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 32 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 598277079 | wnt6 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 598277051 | wnt6 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 625894466 | Wnt6 | Wnt family member 6 | INVOLVED IN axis specification (ortholog); branching involved in ureteric bud morphogenesis (ortholog); epithelial-mesenchymal cell signaling (ortholog); PARTICIPATES IN Wnt signaling pathway; Wnt signaling, canonical pathway; ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); bladder exstrophy-ep ispadias-cloacal exstrophy complex (ortholog); Desbuquois dysplasia (ortholog); FOUND IN cell surface (ortholog); extracellular matrix (ortholog) | | | | Black Rat | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14389766 | Wnt6 | | | | | | Fly | | symbol | gene, null |
| 598276873 | wnt6 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18790182 | WNT6 | Wnt family member 6 | ENCODES a protein that exhibits cytokine activity (inferred); frizzled binding (inferred); signaling receptor binding (inferred); INVOLVED IN axis specification (ortholog); branching involved in ureteric bud morphogenesis (ortholog); epithelial-mesenchymal cell signaling (ortholog); PARTICIPATES IN Wnt signaling pathway; Wnt signaling, canonical pathway; ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); bladder exstrophy-epispadias-cloacal exstrophy complex (ortholog); Desbuquois dysplasia (ortholog); FOUND IN cell surface (inferred); extracellular matrix (inferred); extracellular region (inferred) | | | | Green Monkey | 32 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18936145 | Wnt6 | Wnt family member 6 | ENCODES a protein that exhibits cytokine activity (inferred); frizzled binding (inferred); signaling receptor binding (inferred); INVOLVED IN axis specification (ortholog); branching involved in ureteric bud morphogenesis (ortholog); epithelial-mesenchymal cell signaling (ortholog); PARTICIPATES IN Wnt signaling pathway; Wnt signaling pathway; Wnt signaling, canonical pathway; ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); bladder exstrophy-epispadias-cloacal exstrophy complex (ortholog); Desbuquois dysplasia (ortholog); FOUND IN cell surface (ortholog); extracellular matrix (ortholog) | | | | Naked Mole-Rat | 31 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 1315958 | WNT10A | Wnt family member 10A | The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is strongly expressed in the cell lines of promyelocytic leukemia and Burkitt's lymphoma. In addition, it and another family member, the WNT6 gene, are strongly coexpressed in colorectal cancer cell lines. The gene overexpression may play key roles in carcinogenesis through activation of the WNT-beta-catenin-TCF signaling pathway. This gene and the WNT6 gene are clustered in the chromosome 2q35 region. [provided by RefSeq, Jul 2008] | 2 | 218874116 | 218893928 | Human | 381 | description | gene, protein-coding, REVIEWED [RefSeq] |