| 1307895 | Wee1 | WEE1 G2 checkpoint kinase | ENCODES a protein that exhibits protein kinase activity (ortholog); protein tyrosine kinase activity (ortholog); INVOLVED IN establishment of cell polarity (ortholog); microtubule cytoskeleton organization (ortholog); negative regulation of G2/M transition of mitotic cell cycle (ortholog); PARTICIPA TES IN cell cycle pathway, mitotic; ASSOCIATED WITH head and neck squamous cell carcinoma (ortholog); lung non-small cell carcinoma (ortholog); FOUND IN cytoplasm (ortholog); nucleolus (ortholog); nucleus (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 1 | 173605609 | 173632450 | Rat | 267 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1317355 | WEE1 | WEE1 G2 checkpoint kinase | This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the n ucleus from cytoplasmically activated CDC2 kinase. [provided by RefSeq, Jul 2008] | 11 | 9573670 | 9589985 | Human | 271 | symbol , old_gene_name , COSMIC , name , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1317356 | Wee1 | WEE 1 homolog 1 (S. pombe) | Enables protein kinase activity. Acts upstream of or within several processes, including establishment of cell polarity; neuron projection morphogenesis; and peptidyl-tyrosine phosphorylation. Located in cytoplasm. Is expressed in several structures, including brain ventricular layer; early embryo; gut; humerus; and inferior colliculus. Orthologous to human WEE1 (WEE1 G2 checkpoint kinase). [provided by Alliance of Genome Resources, Jul 2025] | 7 | 109721266 | 109742506 | Mouse | 281 | symbol , old_gene_name , PhenoGen , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 8753807 | Wee1 | WEE1 G2 checkpoint kinase | ENCODES a protein that exhibits protein kinase activity (ortholog); protein tyrosine kinase activity (ortholog); INVOLVED IN establishment of cell polarity (ortholog); microtubule cytoskeleton organization (ortholog); negative regulation of G2/M transition of mitotic cell cycle (ortholog); ASSOCIATE D WITH head and neck squamous cell carcinoma (ortholog); lung non-small cell carcinoma (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog) | NW_004955414 | 25281725 | 25299242 | Chinchilla | 23 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 11956529 | WEE1 | WEE1 G2 checkpoint kinase | ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); magnesium ion binding (inferred); INVOLVED IN establishment of cell polarity (ortholog); microtubule cytoskeleton organization (ortholog); negative regulation of G2/M transition of mitotic cell cycle (ortholog); ASSO CIATED WITH head and neck squamous cell carcinoma (ortholog); lung non-small cell carcinoma (ortholog); FOUND IN nucleus (ortholog) | 11 | 9706531 | 9722528 | Bonobo | 44 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12200977 | WEE1 | WEE1 G2 checkpoint kinase | ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); magnesium ion binding (inferred); INVOLVED IN establishment of cell polarity (ortholog); microtubule cytoskeleton organization (ortholog); neuron projection morphogenesis (ortholog); ASSOCIATED WITH head and neck squ amous cell carcinoma (ortholog); lung non-small cell carcinoma (ortholog); FOUND IN cytoplasm (inferred); nucleolus (inferred); nucleus (inferred) | 21 | 32843263 | 32862114 | Dog | 47 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12736999 | Wee1 | WEE1 G2 checkpoint kinase | ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); magnesium ion binding (inferred); INVOLVED IN establishment of cell polarity (ortholog); microtubule cytoskeleton organization (ortholog); neuron projection morphogenesis (ortholog); ASSOCIATED WITH head and neck squ amous cell carcinoma (ortholog); lung non-small cell carcinoma (ortholog); FOUND IN cytoplasm (inferred); nucleolus (inferred); nucleus (inferred) | NW_004936528 | 8573837 | 8588988 | Squirrel | 47 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 14172461 | WEE1 | WEE1 G2 checkpoint kinase | ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); magnesium ion binding (inferred); INVOLVED IN establishment of cell polarity (ortholog); microtubule cytoskeleton organization (ortholog); neuron projection morphogenesis (ortholog); ASSOCIATED WITH head and neck squ amous cell carcinoma (ortholog); lung non-small cell carcinoma (ortholog); FOUND IN cytoplasm (ortholog); INTERACTS WITH resveratrol | | | | Pig | 49 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 14389028 | Wee1 | | | | | | Fly | | symbol | gene, null |
| 18677321 | WEE1 | WEE1 G2 checkpoint kinase | ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); magnesium ion binding (inferred); INVOLVED IN establishment of cell polarity (ortholog); microtubule cytoskeleton organization (ortholog); neuron projection morphogenesis (ortholog); ASSOCIATED WITH head and neck squ amous cell carcinoma (ortholog); lung non-small cell carcinoma (ortholog); FOUND IN cytoplasm (inferred); nucleolus (inferred); nucleus (inferred) | | | | Green Monkey | 47 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18901542 | Wee1 | WEE1 G2 checkpoint kinase | ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); magnesium ion binding (inferred); INVOLVED IN establishment of cell polarity (ortholog); microtubule cytoskeleton organization (ortholog); negative regulation of G2/M transition of mitotic cell cycle (ortholog); ASSO CIATED WITH head and neck squamous cell carcinoma (ortholog); lung non-small cell carcinoma (ortholog); FOUND IN nucleus (ortholog) | | | | Naked Mole-Rat | 42 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 626088486 | Wee1 | WEE1 G2 checkpoint kinase | ENCODES a protein that exhibits protein kinase activity (ortholog); protein tyrosine kinase activity (ortholog); INVOLVED IN establishment of cell polarity (ortholog); microtubule cytoskeleton organization (ortholog); negative regulation of G2/M transition of mitotic cell cycle (ortholog); ASSOCIATE D WITH head and neck squamous cell carcinoma (ortholog); lung non-small cell carcinoma (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog) | | | | Black Rat | 23 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 626183043 | wee1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626184783 | wee1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626186617 | wee1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 16563909 | AC131274.2 | WEE1 homolog (S. pombe) (WEE1) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 16564000 | AC131274.3 | WEE1 homolog (S. pombe) (WEE1) pseudogene | | | | | Human | | name | gene, transcribed_processed_pseudogene |
| 16558793 | AC253576.1 | pseudogene similar to part of WEE1 homolog (WEE1) | | | | | Human | | name | gene, processed_pseudogene |
| 38663238 | WEE1P1 | WEE1 pseudogene 1 | | 4 | 105761 | 107938 | Human | | symbol , GTEx , old_gene_name , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 38671551 | WEE1P2 | WEE1 pseudogene 2 | | 17 | 22704119 | 22705636 | Human | | symbol , GTEx , old_gene_name , COSMIC , name , Human Proteome Map | gene, pseudo, VALIDATED [RefSeq] |
| 14117100 | LOC100736609 | wee1-like protein kinase | | | | | Pig | | name | gene, pseudo, MODEL [RefSeq] |
| 11677332 | LOC100986792 | wee1-like protein kinase | | 4 | 204635 | 208070 | Bonobo | | old_gene_name , name | gene, pseudo, MODEL [RefSeq] |
| 12046142 | LOC103784627 | wee1-like protein kinase | | 4 | 107975 | 111348 | Bonobo | | old_gene_name , name | gene, pseudo, MODEL [RefSeq] |
| 1617198 | Wee2 | WEE1 homolog 2 (S. pombe) | Predicted to enable protein tyrosine kinase activity. Involved in several processes, including female pronucleus assembly; negative regulation of oocyte maturation; and regulation of phosphorylation. Located in cytoplasm and nucleus. Is expressed in early embryo; olfactory epithelium; and ovary. Ort hologous to human WEE2 (WEE2 oocyte meiosis inhibiting kinase). [provided by Alliance of Genome Resources, Jul 2025] | 6 | 40412180 | 40443749 | Mouse | 53 | old_gene_name , name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 11990078 | LOC100985985 | wee1-like protein kinase 2 | | 11 | 35940221 | 35941957 | Bonobo | | name | gene, pseudo, MODEL [RefSeq] |
| 18929820 | LOC101702827 | wee1-like protein kinase 2 | | | | | Naked Mole-Rat | | name | gene, pseudo, MODEL [RefSeq] |
| 18915732 | LOC101707254 | wee1-like protein kinase 2 | | | | | Naked Mole-Rat | | name | gene, pseudo, MODEL [RefSeq] |
| 18926587 | LOC101721887 | wee1-like protein kinase 2 | | | | | Naked Mole-Rat | | name | gene, pseudo, MODEL [RefSeq] |
| 10086316 | LOC106149337 | wee1-like protein kinase 2 | | NW_004955443 | 6847682 | 6849498 | Chinchilla | | name | gene, pseudo, MODEL [RefSeq] |
| 625932670 | LOC116901194 | wee1-like protein kinase 2 | | | | | Black Rat | | name | gene, pseudo, MODEL [RefSeq] |
| 16560366 | WEE2P1 | WEE2 pseudogene 1 | | 11 | 35966810 | 35968873 | Human | | old_gene_name | gene, pseudo, INFERRED [RefSeq] |
| 38672834 | LOC100288172 | WEE1 homolog (S. pombe) pseudogene | | 4 | 201223 | 205028 | Human | | old_gene_name , name | gene, pseudo, INFERRED [RefSeq] |
| 38669199 | LOC100533640 | WEE1 homolog (S. pombe) pseudogene | | 17 | 22693328 | 22694393 | Human | | name | gene, pseudo, INFERRED [RefSeq] |
| 18382329 | LOC103247305 | wee1-like protein kinase pseudogene | | | | | Green Monkey | | old_gene_name , name | gene, pseudo, MODEL [RefSeq] |
| 8985340 | LOC102004912 | wee1-like protein kinase 2 pseudogene | | NW_004955463 | 3267194 | 3269457 | Chinchilla | | name | gene, pseudo, MODEL [RefSeq] |
| 18516183 | LOC103237585 | wee1-like protein kinase 2 pseudogene | | | | | Green Monkey | | old_gene_name , name | gene, pseudo, MODEL [RefSeq] |
| 18916473 | LOC106008922 | wee1-like protein kinase 2 pseudogene | | | | | Naked Mole-Rat | | name | gene, pseudo, MODEL [RefSeq] |
| 1352233 | WEE2 | WEE2 oocyte meiosis inhibiting kinase | Predicted to enable protein tyrosine kinase activity. Predicted to be involved in several processes, including female pronucleus assembly; negative regulation of cyclin-dependent protein serine/threonine kinase activity; and regulation of meiotic cell cycle. Located in cytosol; nucleoplasm; and plas ma membrane. [provided by Alliance of Genome Resources, Jul 2025] | 7 | 141708353 | 141731271 | Human | 53 | old_gene_name , ensembl_full_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1587197 | Wee2 | WEE2 oocyte meiosis inhibiting kinase | ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); magnesium ion binding (inferred); INVOLVED IN female meiotic nuclear division (ortholog); female pronucleus assembly (ortholog); negative regulation of cyclin-dependent protein serine/threonine kinase activity (ortho log); PARTICIPATES IN cell cycle pathway, mitotic; ASSOCIATED WITH Oocyte Maturation Defect 5 (ortholog); FOUND IN cytoplasm (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH bisphenol A; cadmium dichloride; benzo[a]pyrene (ortholog) | 4 | 70204459 | 70228813 | Rat | 46 | old_gene_name , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |
| 8853652 | Wee2 | WEE2 oocyte meiosis inhibiting kinase | INVOLVED IN female meiotic nuclear division (ortholog); female pronucleus assembly (ortholog); negative regulation of cyclin-dependent protein serine/threonine kinase activity (ortholog); ASSOCIATED WITH Oocyte Maturation Defect 5 (ortholog); FOUND IN cytoplasm (ortholog); nucleoplasm (ortholog); nu cleus (ortholog) | NW_004955494 | 1836909 | 1869384 | Chinchilla | 16 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 11835643 | WEE2 | WEE2 oocyte meiosis inhibiting kinase | ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); magnesium ion binding (inferred); INVOLVED IN negative regulation of cyclin-dependent protein serine/threonine kinase activity (ortholog); negative regulation of meiotic cell cycle process involved in oocyte maturati on (ortholog); negative regulation of oocyte development (ortholog); ASSOCIATED WITH Oocyte Maturation Defect 5 (ortholog); FOUND IN cytoplasm (inferred); nucleoplasm (inferred); nucleus (inferred) | 7 | 133635359 | 133663153 | Bonobo | 37 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12215874 | WEE2 | WEE2 oocyte meiosis inhibiting kinase | ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); magnesium ion binding (inferred); INVOLVED IN female meiotic nuclear division (ortholog); female pronucleus assembly (ortholog); negative regulation of cyclin-dependent protein serine/threonine kinase activity (ortho log); ASSOCIATED WITH Oocyte Maturation Defect 5 (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog) | 16 | 7466651 | 7485150 | Dog | 44 | old_gene_name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 12513242 | Wee2 | WEE2 oocyte meiosis inhibiting kinase | INVOLVED IN female meiotic nuclear division (ortholog); female pronucleus assembly (ortholog); negative regulation of cyclin-dependent protein serine/threonine kinase activity (ortholog); ASSOCIATED WITH Oocyte Maturation Defect 5 (ortholog); FOUND IN cytoplasm (ortholog); nucleoplasm (ortholog); nu cleus (ortholog) | NW_004936592 | 5584064 | 5608985 | Squirrel | 16 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 13984665 | WEE2 | WEE2 oocyte meiosis inhibiting kinase | ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); magnesium ion binding (inferred); INVOLVED IN female meiotic nuclear division; negative regulation of meiotic cell cycle process involved in oocyte maturation; negative regulation of oocyte development; ASSOCIATED WI TH Oocyte Maturation Defect 5 (ortholog); FOUND IN nucleus | | | | Pig | 42 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 18455965 | WEE2 | WEE2 oocyte meiosis inhibiting kinase | ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); magnesium ion binding (inferred); INVOLVED IN negative regulation of cyclin-dependent protein serine/threonine kinase activity (ortholog); negative regulation of meiotic cell cycle process involved in oocyte maturati on (ortholog); negative regulation of oocyte development (ortholog); ASSOCIATED WITH Oocyte Maturation Defect 5 (ortholog); FOUND IN cytoplasm (inferred); nucleoplasm (inferred); nucleus (inferred) | | | | Green Monkey | 37 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18900841 | Wee2 | WEE2 oocyte meiosis inhibiting kinase | ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); magnesium ion binding (inferred); INVOLVED IN female meiotic nuclear division (ortholog); female pronucleus assembly (ortholog); negative regulation of cyclin-dependent protein serine/threonine kinase activity (ortho log); ASSOCIATED WITH Oocyte Maturation Defect 5 (ortholog); FOUND IN nucleoplasm (ortholog) | | | | Naked Mole-Rat | 35 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 626161023 | Wee2 | WEE2 oocyte meiosis inhibiting kinase | INVOLVED IN female meiotic nuclear division (ortholog); female pronucleus assembly (ortholog); negative regulation of cyclin-dependent protein serine/threonine kinase activity (ortholog); ASSOCIATED WITH Oocyte Maturation Defect 5 (ortholog); FOUND IN cytoplasm (ortholog); nucleoplasm (ortholog); nu cleus (ortholog) | | | | Black Rat | 16 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 41243557 | Wee2-ps1 | WEE2 oocyte meiosis inhibiting kinase, pseudogene 1 | | 5 | 40348476 | 40349763 | Rat | | old_gene_name | gene, pseudo, MODEL [RefSeq] |