Wee1 (WEE1 G2 checkpoint kinase) - Rat Genome Database

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Gene: Wee1 (WEE1 G2 checkpoint kinase) Heterocephalus glaber
Analyze
Symbol: Wee1
Name: WEE1 G2 checkpoint kinase
RGD ID: 18901542
Description: ENCODES a protein that exhibits protein kinase activity (ortholog); protein tyrosine kinase activity (ortholog); INVOLVED IN establishment of cell polarity (ortholog); microtubule cytoskeleton organization (ortholog); negative regulation of G2/M transition of mitotic cell cycle (ortholog); ASSOCIATED WITH genetic disease (ortholog); head and neck squamous cell carcinoma (ortholog); lung non-small cell carcinoma (ortholog); FOUND IN cytoplasm (ortholog); nucleolus (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: WEE1 homolog; wee1-like protein kinase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247661,687,044 - 1,701,785 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247661,687,088 - 1,706,185 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO)
nucleolus  (ISO)
nucleus  (ISO)

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Wee1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247661,687,044 - 1,701,785 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247661,687,088 - 1,706,185 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
WEE1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38119,573,670 - 9,589,985 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl119,573,670 - 9,593,457 (+)EnsemblGRCh38hg38GRCh38
GRCh37119,595,217 - 9,611,532 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36119,550,916 - 9,567,874 (+)NCBINCBI36Build 36hg18NCBI36
Build 34119,550,915 - 9,567,874NCBI
Celera119,716,710 - 9,732,726 (+)NCBICelera
Cytogenetic Map11p15.4NCBI
HuRef119,266,900 - 9,282,930 (+)NCBIHuRef
CHM1_1119,594,205 - 9,610,219 (+)NCBICHM1_1
T2T-CHM13v2.0119,657,890 - 9,674,136 (+)NCBIT2T-CHM13v2.0
Wee1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397109,721,266 - 109,742,506 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7109,721,253 - 109,742,493 (+)EnsemblGRCm39 Ensembl
GRCm387110,122,059 - 110,143,299 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7110,122,046 - 110,143,286 (+)EnsemblGRCm38mm10GRCm38
MGSCv377117,265,573 - 117,286,813 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367109,913,236 - 109,934,463 (+)NCBIMGSCv36mm8
Celera7110,095,829 - 110,117,069 (+)NCBICelera
Cytogenetic Map7E3NCBI
cM Map757.7NCBI
Wee1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81173,605,609 - 173,632,450 (+)NCBIGRCr8
mRatBN7.21164,173,681 - 164,197,688 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1164,174,779 - 164,197,688 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1172,511,086 - 172,529,507 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01179,697,089 - 179,715,510 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01172,379,478 - 172,397,737 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01174,765,228 - 174,790,882 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1174,767,960 - 174,786,361 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01181,766,494 - 181,790,794 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41167,769,797 - 167,788,199 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11167,880,459 - 167,898,861 (+)NCBI
Celera1162,072,157 - 162,090,576 (+)NCBICelera
Cytogenetic Map1q33NCBI
Wee1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541425,281,689 - 25,298,096 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541425,281,725 - 25,299,242 (+)NCBIChiLan1.0ChiLan1.0
WEE1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2912,013,281 - 12,029,241 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11111,972,062 - 11,992,213 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0119,706,531 - 9,722,528 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1119,437,847 - 9,452,548 (+)NCBIpanpan1.1PanPan1.1panPan2
WEE1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12132,843,263 - 32,862,114 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2132,843,320 - 32,862,130 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2132,410,744 - 32,429,606 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02133,721,937 - 33,740,772 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2133,722,005 - 33,737,604 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12132,985,133 - 33,003,990 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02133,151,707 - 33,170,570 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02133,445,593 - 33,464,455 (+)NCBIUU_Cfam_GSD_1.0
Wee1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494752,539,632 - 52,554,844 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365288,573,497 - 8,588,576 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365288,573,837 - 8,588,988 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WEE1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl249,880,435 - 49,894,499 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1249,880,416 - 49,894,509 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2253,229,796 - 53,243,875 (-)NCBISscrofa10.2Sscrofa10.2susScr3
WEE1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1155,225,615 - 55,247,112 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl155,231,292 - 55,245,859 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038152,911,791 - 152,927,857 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000012500   ⟹   ENSHGLP00000012365
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247661,687,044 - 1,701,785 (+)Ensembl
RefSeq Acc Id: XM_004851408   ⟹   XP_004851465
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247661,687,088 - 1,702,869 (+)NCBI
RefSeq Acc Id: XM_021263783   ⟹   XP_021119442
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247661,687,088 - 1,706,185 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004851465 (Get FASTA)   NCBI Sequence Viewer  
  XP_021119442 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000012365
Reference Protein Sequences
RefSeq Acc Id: XP_021119442   ⟸   XM_021263783
- Peptide Label: isoform X2
RefSeq Acc Id: XP_004851465   ⟸   XM_004851408
- Peptide Label: isoform X1
RefSeq Acc Id: ENSHGLP00000012365   ⟸   ENSHGLT00000012500


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000008834 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000012500 ENTREZGENE
NCBI Gene Wee1 ENTREZGENE