| 620421 | Vamp8 | vesicle-associated membrane protein 8 | ENCODES a protein that exhibits SNAP receptor activity; syntaxin binding; chloride channel inhibitor activity (ortholog); INVOLVED IN membrane fusion; protein-containing complex assembly; vesicle fusion; ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); carcinoma (ortholog); coronary artery disea se (ortholog); FOUND IN late endosome membrane; lysosomal membrane; midbody; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 4 | 106000570 | 106011081 | Rat | 229 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 731713 | Vamp8 | vesicle-associated membrane protein 8 | Predicted to enable SNAP receptor activity; chloride channel inhibitor activity; and syntaxin binding activity. Involved in SNARE complex assembly and mucus secretion. Acts upstream of or within several processes, including cellular response to type II interferon; positive regulation of pancreatic a mylase secretion; and zymogen granule exocytosis. Located in several cellular components, including basolateral part of cell; basolateral plasma membrane; and cytoplasmic vesicle. Part of SNARE complex. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and hemolymphoid system. Orthologous to human VAMP8 (vesicle associated membrane protein 8). [provided by Alliance of Genome Resources, Jul 2025] | 6 | 72362204 | 72367650 | Mouse | 249 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1347649 | VAMP8 | vesicle associated membrane protein 8 | This gene encodes an integral membrane protein that belongs to the synaptobrevin/vesicle-associated membrane protein subfamily of soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs). The encoded protein is involved in the fusion of synaptic vesicles with the presynaptic m embrane.[provided by RefSeq, Jun 2010] | 2 | 85577586 | 85582031 | Human | 220 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 8817657 | Vamp8 | vesicle associated membrane protein 8 | ENCODES a protein that exhibits chloride channel inhibitor activity (ortholog); SNAP receptor activity (ortholog); syntaxin binding (ortholog); INVOLVED IN autophagosome maturation (ortholog); autophagosome membrane docking (ortholog); cellular response to type II interferon (ortholog); ASSOCIATED W ITH Animal Mammary Neoplasms (ortholog); carcinoma (ortholog); coronary artery disease (ortholog); FOUND IN azurophil granule membrane (ortholog); basal part of cell (ortholog); basolateral part of cell (ortholog) | NW_004955424 | 1922830 | 1926844 | Chinchilla | 68 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11737331 | VAMP8 | vesicle associated membrane protein 8 | ENCODES a protein that exhibits SNAP receptor activity (ortholog); syntaxin binding (ortholog); INVOLVED IN cellular response to type II interferon (ortholog); eosinophil degranulation (ortholog); membrane fusion (ortholog); ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); carcinoma (ortholog); coronary artery disease (ortholog); FOUND IN basal part of cell (ortholog); basolateral part of cell (ortholog); basolateral plasma membrane (ortholog) | 2A | 85627678 | 85632205 | Bonobo | 80 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12339800 | VAMP8 | vesicle associated membrane protein 8 | ENCODES a protein that exhibits chloride channel inhibitor activity (ortholog); syntaxin binding (ortholog); INVOLVED IN autophagosome maturation (ortholog); autophagosome membrane docking (ortholog); cellular response to type II interferon (ortholog); ASSOCIATED WITH Animal Mammary Neoplasms (ortho log); carcinoma (ortholog); coronary artery disease (ortholog); FOUND IN azurophil granule membrane (ortholog); basal part of cell (ortholog); basolateral part of cell (ortholog); INTERACTS WITH bisphenol A | 17 | 39497628 | 39501734 | Dog | 79 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12681959 | Vamp8 | vesicle associated membrane protein 8 | ENCODES a protein that exhibits SNAP receptor activity (ortholog); syntaxin binding (ortholog); INVOLVED IN cellular response to type II interferon (ortholog); eosinophil degranulation (ortholog); membrane fusion (ortholog); ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); carcinoma (ortholog); coronary artery disease (ortholog); FOUND IN basal part of cell (ortholog); basolateral part of cell (ortholog); basolateral plasma membrane (ortholog) | NW_004936712 | 1688126 | 1689742 | Squirrel | 70 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18471184 | VAMP8 | vesicle associated membrane protein 8 | ENCODES a protein that exhibits SNAP receptor activity (ortholog); syntaxin binding (ortholog); INVOLVED IN cellular response to type II interferon (ortholog); eosinophil degranulation (ortholog); membrane fusion (ortholog); ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); carcinoma (ortholog); coronary artery disease (ortholog); FOUND IN basal part of cell (ortholog); basolateral part of cell (ortholog); basolateral plasma membrane (ortholog) | | | | Green Monkey | 79 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 287715849 | vamp8 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 14098512 | VAMP8 | vesicle associated membrane protein 8 | ENCODES a protein that exhibits syntaxin binding (ortholog); INVOLVED IN cellular response to type II interferon (ortholog); eosinophil degranulation (ortholog); membrane fusion (ortholog); ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); carcinoma (ortholog); coronary artery disease (ortholog); FOUND IN basal part of cell (ortholog); basolateral part of cell (ortholog); basolateral plasma membrane (ortholog) | | | | Pig | 83 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18932643 | Vamp8 | vesicle associated membrane protein 8 | ENCODES a protein that exhibits chloride channel inhibitor activity (ortholog); SNAP receptor activity (ortholog); syntaxin binding (ortholog); INVOLVED IN autophagosome maturation (ortholog); autophagosome membrane docking (ortholog); cellular response to type II interferon (ortholog); ASSOCIATED W ITH Animal Mammary Neoplasms (ortholog); carcinoma (ortholog); coronary artery disease (ortholog); FOUND IN azurophil granule membrane (ortholog); basal part of cell (ortholog); basolateral part of cell (ortholog) | | | | Naked Mole-Rat | 77 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 284921880 | vamp8.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 286741654 | vamp8.S | | | | | | African Clawed Frog | | symbol | gene, null |