Ube2b Gene Search Result

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15 records found for search term Ube2b

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
708345	Ube2b	ubiquitin-conjugating enzyme E2B	ENCODES a protein that exhibits ubiquitin conjugating enzyme activity (ortholog); ubiquitin protein ligase binding (ortholog); ubiquitin-protein transferase activity (ortholog); INVOLVED IN cellular response to insulin stimulus; response to hypoxia; ubiquitin-dependent protein catabolic process; PAR ... (more) TICIPATES IN ubiquitin/proteasome degradation pathway; ASSOCIATED WITH Hereditary Neoplastic Syndromes (ortholog); FOUND IN chromatin (ortholog); cytoplasm (ortholog); HULC complex (ortholog); INTERACTS WITH (+)-schisandrin B; 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine	10	36749365	36764335	Rat	199	symbol , PhenoGen	gene, protein-coding, VALIDATED [RefSeq]
734012	Ube2b	ubiquitin-conjugating enzyme E2B	Enables ubiquitin conjugating enzyme activity and ubiquitin protein ligase binding activity. Involved in positive regulation of canonical Wnt signaling pathway. Acts upstream of or within several processes, including chromosome organization; regulation of primary metabolic process; and sperm axoneme ... (more) assembly. Located in XY body and chromatin. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and integumental system. Orthologous to human UBE2B (ubiquitin conjugating enzyme E2 B). [provided by Alliance of Genome Resources, Jul 2025]	11	51875965	51894972	Mouse	245	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
1349526	UBE2B	ubiquitin conjugating enzyme E2 B	The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ... (more) ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100% identical to the mouse, rat, and rabbit homologs, which indicates that this enzyme is highly conserved in eukaryotic evolution. [provided by RefSeq, Jul 2008]	5	134371569	134392108	Human	191	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
8806623	Ube2b	ubiquitin conjugating enzyme E2 B	ENCODES a protein that exhibits ubiquitin conjugating enzyme activity (ortholog); ubiquitin protein ligase binding (ortholog); ubiquitin-protein transferase activity (ortholog); INVOLVED IN cellular response to insulin stimulus (ortholog); chiasma assembly (ortholog); chromatin organization (ortholo ... (more) g); ASSOCIATED WITH Hereditary Neoplastic Syndromes (ortholog); FOUND IN chromatin (ortholog); cytoplasm (ortholog); HULC complex (ortholog)	NW_004955408	5552619	5572145	Chinchilla	50	symbol	gene, protein-coding, MODEL [RefSeq]
12006787	UBE2B	ubiquitin conjugating enzyme E2 B	ENCODES a protein that exhibits ATP binding (inferred); nucleotide binding (inferred); transferase activity (inferred); INVOLVED IN cellular response to insulin stimulus (ortholog); chiasma assembly (ortholog); chromatin organization (ortholog); ASSOCIATED WITH Hereditary Neoplastic Syndromes (ortho ... (more) log); FOUND IN chromatin (inferred); cytoplasm (inferred); HULC complex (inferred)	5	129775011	129794853	Bonobo	55	symbol	gene, protein-coding, MODEL [RefSeq]
12342010	UBE2B	ubiquitin conjugating enzyme E2 B	ENCODES a protein that exhibits ubiquitin protein ligase binding (ortholog); ubiquitin-protein transferase activity (ortholog); INVOLVED IN cellular response to insulin stimulus (ortholog); chiasma assembly (ortholog); chromatin organization (ortholog); ASSOCIATED WITH Hereditary Neoplastic Syndrome ... (more) s (ortholog); FOUND IN chromatin (ortholog); cytoplasm (ortholog); nucleus (ortholog)	11	22523671	22541473	Dog	54	symbol	gene, protein-coding, MODEL [RefSeq]
12651546	Ube2b	ubiquitin conjugating enzyme E2 B	ENCODES a protein that exhibits ATP binding (inferred); nucleotide binding (inferred); transferase activity (inferred); INVOLVED IN cellular response to insulin stimulus (ortholog); chiasma assembly (ortholog); chromatin organization (ortholog); ASSOCIATED WITH Hereditary Neoplastic Syndromes (ortho ... (more) log); FOUND IN chromatin (inferred); cytoplasm (inferred); HULC complex (inferred)	NW_004936647	891357	913963	Squirrel	52	symbol	gene, protein-coding, MODEL [RefSeq]
18412028	UBE2B	ubiquitin conjugating enzyme E2 B	ENCODES a protein that exhibits ATP binding (inferred); nucleotide binding (inferred); transferase activity (inferred); INVOLVED IN cellular response to insulin stimulus (ortholog); chiasma assembly (ortholog); chromatin organization (ortholog); ASSOCIATED WITH Hereditary Neoplastic Syndromes (ortho ... (more) log); FOUND IN chromatin (inferred); cytoplasm (inferred); HULC complex (inferred)				Green Monkey	55	symbol	gene, protein-coding, MODEL [RefSeq]
18923721	Ube2b	ubiquitin conjugating enzyme E2 B	ENCODES a protein that exhibits ubiquitin protein ligase binding (ortholog); ubiquitin-protein transferase activity (ortholog); INVOLVED IN cellular response to insulin stimulus (ortholog); chiasma assembly (ortholog); chromatin organization (ortholog); ASSOCIATED WITH Hereditary Neoplastic Syndrome ... (more) s (ortholog); FOUND IN chromatin (ortholog); cytoplasm (ortholog); HULC complex (ortholog)				Naked Mole-Rat	51	symbol	gene, protein-coding, MODEL [RefSeq]
626004512	Ube2b	ubiquitin conjugating enzyme E2 B	ENCODES a protein that exhibits ubiquitin conjugating enzyme activity (ortholog); ubiquitin protein ligase binding (ortholog); ubiquitin-protein transferase activity (ortholog); INVOLVED IN cellular response to insulin stimulus (ortholog); chiasma assembly (ortholog); chromatin organization (ortholo ... (more) g); FOUND IN chromatin (ortholog); cytoplasm (ortholog); HULC complex (ortholog)				Black Rat	49	symbol	gene, protein-coding, MODEL [RefSeq]
155237027	ube2b						Tropical Clawed Frog		symbol	gene, null
13855565	UBE2B	ubiquitin conjugating enzyme E2 B	ENCODES a protein that exhibits ATP binding (inferred); nucleotide binding (inferred); transferase activity (inferred); INVOLVED IN cellular response to insulin stimulus (ortholog); chiasma assembly (ortholog); chromatin organization (ortholog); ASSOCIATED WITH Hereditary Neoplastic Syndromes (ortho ... (more) log); FOUND IN chromatin (inferred); cytoplasm (inferred); HULC complex (inferred)				Pig	57	symbol	gene, protein-coding, PROVISIONAL [RefSeq]
155239272	ube2b.L						African Clawed Frog		symbol	gene, null
155246526	ube2b.S						African Clawed Frog		symbol	gene, null
1602731	AUP1	AUP1 lipid droplet regulating VLDL assembly factor	The protein encoded this gene is involved in several pathways including quality control of misfolded proteins in the endoplasmic reticulum and lipid droplet accumulation. Lipid droplets are organelles in the cytoplasm that store neutral lipids such as cholesterol esters and trigylycerides to prevent ... (more) the overabundance of free cholesterol and fatty acids in cells, but also to act as storage for other metabolic processes, such as membrane biogenesis. Reduced expression of this gene results in reduced lipid droplet clustering, a function that is dependent on ubiquitination of the protein. This protein contains multiple domains including a hydrophobic N-terminal domain, an acetyltranferase domain, a ubiquitin-binding CUE domain, and a UBE2B2-binding domain (G2BR). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]	2	74526652	74529706	Human	85	description	gene, protein-coding, REVIEWED [RefSeq]