ENCODES a protein that exhibits enzyme binding; protein homodimerization activity (ortholog); protein-disulfide reductase [NAD(P)H] activity (ortholog); INVOLVED IN cellular response to antibiotic; cellular response to glucose stimulus; cellular response to hyperoxia; PARTICIPATES IN adenine phoshor
Enables protein-disulfide reductase activity. Acts upstream of or within cell redox homeostasis; negative regulation of protein export from nucleus; and negative regulation of transcription by RNA polymerase II. Located in cytosol and nucleus. Is expressed in several structures, including central ne
rvous system; skeleton; and submandibular gland primordium. Orthologous to human TXN (thioredoxin). [provided by Alliance of Genome Resources, Jul 2025]
The protein encoded by this gene acts as a homodimer and is involved in many redox reactions. The encoded protein is active in the reversible S-nitrosylation of cysteines in certain proteins, which is part of the response to intracellular nitric oxide. This protein is found in the cytoplasm. Two tra