| 620636 | Trpv5 | transient receptor potential cation channel, subfamily V, member 5 | ENCODES a protein that exhibits calcium channel activity; INVOLVED IN calcium ion transmembrane transport; calcium ion transport into cytosol; calcium ion homeostasis (ortholog); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH gestational diabet es (ortholog); pre-eclampsia (ortholog); FOUND IN apical plasma membrane; plasma membrane; calcium channel complex (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; amitrole | 4 | 71503085 | 71531134 | Rat | 130 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1350143 | TRPV5 | transient receptor potential cation channel subfamily V member 5 | This gene is a member of the transient receptor family and the TrpV subfamily. The calcium-selective channel encoded by this gene has 6 transmembrane-spanning domains, multiple potential phosphorylation sites, an N-linked glycosylation site, and 5 ANK repeats. This protein forms homotetramers or het erotetramers and is activated by a low internal calcium level. [provided by RefSeq, Jul 2008] | 7 | 142908101 | 142933746 | Human | 119 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1551251 | Trpv5 | transient receptor potential cation channel, subfamily V, member 5 | Enables calcium channel activity. Involved in calcium ion homeostasis; calcium ion transmembrane transport; and regulation of urine volume. Located in apical plasma membrane. Part of calcium channel complex. Is expressed in central nervous system; extraembryonic component; metanephros; placenta; and sensory organ. Orthologous to human TRPV5 (transient receptor potential cation channel subfamily V member 5). [provided by Alliance of Genome Resources, Jul 2025] | 6 | 41628595 | 41658158 | Mouse | 158 | symbol , PhenoGen , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 12413938 | TRPV5 | transient receptor potential cation channel subfamily V member 5 | ENCODES a protein that exhibits calcium channel activity (ortholog); INVOLVED IN calcium ion transport into cytosol (ortholog); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH gestational diabetes (ortholog); pre-eclampsia (ortholog); FOUND IN a pical plasma membrane (ortholog) | 16 | 6647070 | 6678080 | Dog | 40 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12450334 | Trpv5 | transient receptor potential cation channel subfamily V member 5 | ENCODES a protein that exhibits calcium channel activity (ortholog); INVOLVED IN calcium ion transport into cytosol (ortholog); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH gestational diabetes (ortholog); pre-eclampsia (ortholog); FOUND IN a pical plasma membrane (ortholog) | NW_004936527 | 375922 | 399446 | Squirrel | 43 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14157647 | TRPV5 | transient receptor potential cation channel subfamily V member 5 | ENCODES a protein that exhibits calcium channel activity (ortholog); INVOLVED IN calcium ion transport into cytosol (ortholog); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH gestational diabetes (ortholog); pre-eclampsia (ortholog); FOUND IN a pical plasma membrane (ortholog); INTERACTS WITH deoxynivalenol | | | | Pig | 49 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13990585 | TRPV5 | transient receptor potential cation channel subfamily V member 5 | ENCODES a protein that exhibits calcium channel activity (ortholog); INVOLVED IN calcium ion homeostasis (ortholog); calcium ion import (ortholog); calcium ion transport (ortholog); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH Desbuquois dysp lasia (ortholog); genetic disease (ortholog); gestational diabetes (ortholog); FOUND IN apical plasma membrane (inferred); calcium channel complex (inferred); membrane (inferred) | | | | Pig | 54 | symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 18593409 | TRPV5 | transient receptor potential cation channel subfamily V member 5 | ENCODES a protein that exhibits calcium channel activity (ortholog); INVOLVED IN calcium ion transport into cytosol (ortholog); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH gestational diabetes (ortholog); pre-eclampsia (ortholog); FOUND IN a pical plasma membrane (ortholog) | | | | Green Monkey | 41 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 288083374 | trpv5 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626118089 | Trpv5 | transient receptor potential cation channel subfamily V member 5 | ENCODES a protein that exhibits calcium channel activity (ortholog); INVOLVED IN calcium ion homeostasis (ortholog); calcium ion import across plasma membrane (ortholog); calcium ion transmembrane transport (ortholog); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pat hway; ASSOCIATED WITH gestational diabetes (ortholog); pre-eclampsia (ortholog); FOUND IN apical plasma membrane (ortholog); calcium channel complex (ortholog); plasma membrane (ortholog) | | | | Black Rat | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 288057028 | trpv5.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 11671015 | LOC100989368 | Kell metallo-endopeptidase (Kell blood group) | ENCODES a protein that exhibits calcium channel activity (inferred); calmodulin binding (inferred); hydrolase activity (inferred); INVOLVED IN intracellular calcium ion homeostasis (ortholog); intracellular magnesium ion homeostasis (ortholog); myelination (ortholog); ASSOCIATED WITH hemolytic disea se of the fetus (ortholog); Vein of Galen Aneurysm (ortholog); FOUND IN apical plasma membrane (inferred); calcium channel complex (inferred); membrane (inferred) | 7 | 134897567 | 135237214 | Bonobo | 55 | ensembl_gene_symbol , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 9052463 | LOC102003250 | transient receptor potential cation channel subfamily V member 5 | | NW_004955494 | 693654 | 721271 | Chinchilla | | ensembl_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 731367 | TRPV6 | transient receptor potential cation channel subfamily V member 6 | This gene encodes a member of a family of multipass membrane proteins that functions as calcium channels. The encoded protein contains N-terminal ankyrin repeats, which are required for channel assembly and regulation. Translation initiation for this protein occurs at a non-AUG start codon that is d ecoded as methionine. This gene is situated next to a closely related gene for transient receptor potential cation channel subfamily V member 5 (TRPV5). This locus has experienced positive selection in non-African populations, resulting in several non-synonymous codon differences among individuals of different genetic backgrounds. [provided by RefSeq, Feb 2015] | 7 | 142871208 | 142885745 | Human | 329 | description | gene, protein-coding, REVIEWED [RefSeq] |