| 1309761 | Traip | TRAF-interacting protein | ENCODES a protein that exhibits identical protein binding (ortholog); ubiquitin protein ligase activity (ortholog); ubiquitin-protein transferase activity (ortholog); INVOLVED IN DNA damage response (ortholog); negative regulation of interferon-beta production (ortholog); negative regulation of tumo r necrosis factor-mediated signaling pathway (ortholog); ASSOCIATED WITH Desbuquois dysplasia (ortholog); Dwarfism (ortholog); genetic disease (ortholog); FOUND IN nucleolus (ortholog); nucleoplasm (ortholog); plasma membrane (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 1H-pyrazole | 8 | 117520476 | 117540253 | Rat | 147 | symbol , old_gene_name , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1320271 | Traip | TRAF-interacting protein | Enables ubiquitin protein ligase activity. Involved in negative regulation of interferon-beta production and protein ubiquitination. Acts upstream of or within negative regulation of NF-kappaB transcription factor activity and signal transduction. Predicted to be located in nucleolus and nucleoplasm . Predicted to be active in nucleus and site of DNA damage. Is expressed in several structures, including central nervous system; genitourinary system; liver; retina layer; and spleen. Human ortholog(s) of this gene implicated in Seckel syndrome 9. Orthologous to human TRAIP (TRAF interacting protein). [provided by Alliance of Genome Resources, Jul 2025] | 9 | 107828158 | 107849469 | Mouse | 157 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1601884 | TRAIP | TRAF interacting protein | This gene encodes a protein that contains an N-terminal RING finger motif and a putative coiled-coil domain. A similar murine protein interacts with TNFR-associated factor 1 (TRAF1), TNFR-associated factor 2 (TRAF2), and cylindromatosis. The interaction with TRAF2 inhibits TRAF2-mediated nuclear fac tor kappa-B, subunit 1 activation that is required for cell activation and protection against apoptosis. [provided by RefSeq, Jul 2008] | 3 | 49828601 | 49856564 | Human | 250 | symbol , old_gene_name , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 8919893 | Traip | TRAF interacting protein | ENCODES a protein that exhibits identical protein binding (ortholog); ubiquitin protein ligase activity (ortholog); ubiquitin-protein transferase activity (ortholog); INVOLVED IN DNA damage response (ortholog); negative regulation of interferon-beta production (ortholog); negative regulation of tumo r necrosis factor-mediated signaling pathway (ortholog); ASSOCIATED WITH Desbuquois dysplasia (ortholog); Dwarfism (ortholog); genetic disease (ortholog); FOUND IN nucleolus (ortholog); nucleoplasm (ortholog); plasma membrane (ortholog) | NW_004955532 | 1725608 | 1746690 | Chinchilla | 32 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 11732320 | TRAIP | TRAF interacting protein | ENCODES a protein that exhibits identical protein binding (inferred); metal ion binding (inferred); transferase activity (inferred); INVOLVED IN obsolete negative regulation of NF-kappaB transcription factor activity (ortholog); signal transduction (ortholog); ASSOCIATED WITH Desbuquois dysplasia (o rtholog); Dwarfism (ortholog); genetic disease (ortholog); FOUND IN chromosome (inferred); nucleolus (inferred); nucleoplasm (inferred) | 3 | 49760528 | 49789637 | Bonobo | 46 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12189665 | TRAIP | TRAF interacting protein | ENCODES a protein that exhibits identical protein binding (inferred); metal ion binding (inferred); transferase activity (inferred); INVOLVED IN obsolete negative regulation of NF-kappaB transcription factor activity (ortholog); signal transduction (ortholog); ASSOCIATED WITH Desbuquois dysplasia (o rtholog); Dwarfism (ortholog); genetic disease (ortholog); FOUND IN chromosome (inferred); nucleolus (inferred); nucleoplasm (inferred) | 20 | 39430109 | 39454437 | Dog | 46 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12579796 | Traip | TRAF interacting protein | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN negative regulation of interferon-beta production (ortholog); negative regulation of tumor necrosis factor-mediated signaling pathway (ortholog); obsolete negative regulation of NF-kappaB transcription factor activity (ortholog); ASSOCIATED WITH Desbuquois dysplasia (ortholog); Dwarfism (ortholog); genetic disease (ortholog); FOUND IN nucleolus (ortholog); plasma membrane (ortholog) | NW_004936529 | 1434629 | 1466382 | Squirrel | 39 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 13910928 | TRAIP | TRAF interacting protein | ENCODES a protein that exhibits ATP binding (inferred); identical protein binding (inferred); ISG15 activating enzyme activity (inferred); INVOLVED IN obsolete negative regulation of NF-kappaB transcription factor activity (ortholog); signal transduction (ortholog); ASSOCIATED WITH Desbuquois dyspla sia (ortholog); Dwarfism (ortholog); genetic disease (ortholog); FOUND IN chromosome (inferred); cytoplasm (inferred); nucleolus (inferred) | | | | Pig | 56 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18632051 | TRAIP | TRAF interacting protein | ENCODES a protein that exhibits identical protein binding (inferred); metal ion binding (inferred); transferase activity (inferred); INVOLVED IN obsolete negative regulation of NF-kappaB transcription factor activity (ortholog); signal transduction (ortholog); ASSOCIATED WITH Desbuquois dysplasia (o rtholog); Dwarfism (ortholog); genetic disease (ortholog); FOUND IN chromosome (inferred); nucleolus (inferred); nucleoplasm (inferred) | | | | Green Monkey | 46 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 155250267 | traip | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626066710 | Traip | TRAF interacting protein | ENCODES a protein that exhibits identical protein binding (ortholog); ubiquitin protein ligase activity (ortholog); ubiquitin-protein transferase activity (ortholog); INVOLVED IN DNA damage response (ortholog); negative regulation of interferon-beta production (ortholog); negative regulation of tumo r necrosis factor-mediated signaling pathway (ortholog); ASSOCIATED WITH Desbuquois dysplasia (ortholog); Dwarfism (ortholog); genetic disease (ortholog); FOUND IN nucleolus (ortholog); nucleoplasm (ortholog); plasma membrane (ortholog) | | | | Black Rat | 32 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18915239 | Traip | TRAF interacting protein | ENCODES a protein that exhibits identical protein binding (ortholog); ubiquitin-protein transferase activity (ortholog); INVOLVED IN DNA damage response (ortholog); negative regulation of interferon-beta production (ortholog); negative regulation of tumor necrosis factor-mediated signaling pathway ( ortholog); ASSOCIATED WITH Desbuquois dysplasia (ortholog); Dwarfism (ortholog); genetic disease (ortholog); FOUND IN nucleolus (ortholog); nucleoplasm (ortholog); plasma membrane (ortholog) | | | | Naked Mole-Rat | 33 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 155256714 | traip.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 12650259 | LOC101962452 | E3 ubiquitin-protein ligase TRAIP-like | ENCODES a protein that exhibits ubiquitin protein ligase activity (inferred); INVOLVED IN protein ubiquitination (inferred); replication fork processing (inferred); FOUND IN nucleus (inferred); site of DNA damage (inferred) | NW_004936753 | 1691411 | 1692810 | Squirrel | 5 | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12666171 | LOC101964774 | E3 ubiquitin-protein ligase TRAIP-like | | NW_004936620 | 4418820 | 4425875 | Squirrel | | name | gene, protein-coding, MODEL [RefSeq] |