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19 records found for search term Tirap
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
1322402TIRAPTIR domain containing adaptor proteinThe innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsi11126283093126294933Human167symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1322403Tiraptoll-interleukin 1 receptor (TIR) domain-containing adaptor proteinEnables several functions, including Toll-like receptor 2 binding activity; identical protein binding activity; and phosphatidylinositol-4,5-bisphosphate binding activity. Involved in several processes, including positive regulation of B cell proliferation; positive regulation of innate immune respo93509568735111587Mouse191symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
1595496TirapTIR domain containing adaptor proteinENCODES a protein that exhibits identical protein binding (ortholog); molecular adaptor activity (ortholog); phosphatidylinositol-4,5-bisphosphate binding (ortholog); INVOLVED IN 3'-UTR-mediated mRNA stabilization (ortholog); cell surface receptor signaling pathway (ortholog); cellular response to b84178955741805903Rat164symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
8941477TirapTIR domain containing adaptor proteinENCODES a protein that exhibits identical protein binding (ortholog); molecular adaptor activity (ortholog); phosphatidylinositol-4,5-bisphosphate binding (ortholog); INVOLVED IN 3'-UTR-mediated mRNA stabilization (ortholog); cell surface receptor signaling pathway (ortholog); cellular response to bNW_0049554122730354827315031Chinchilla82symbolgene, protein-coding, MODEL [RefSeq]
11776357TIRAPTIR domain containing adaptor proteinENCODES a protein that exhibits phosphatidylinositol-4,5-bisphosphate binding (ortholog); INVOLVED IN cell surface receptor signaling pathway (ortholog); cellular response to bacterial lipopeptide (ortholog); cellular response to lipoteichoic acid (ortholog); PARTICIPATES IN Toll-like receptor signa11121100558121112844Bonobo93symbolgene, protein-coding, PROVISIONAL [RefSeq]
12299204TIRAPTIR domain containing adaptor proteinENCODES a protein that exhibits phosphatidylinositol-4,5-bisphosphate binding (ortholog); INVOLVED IN cell surface receptor signaling pathway (ortholog); cellular response to bacterial lipopeptide (ortholog); cellular response to lipoteichoic acid (ortholog); PARTICIPATES IN Toll-like receptor signa582222178237595Dog92symbolgene, protein-coding, MODEL [RefSeq]
12691494TirapTIR domain containing adaptor proteinENCODES a protein that exhibits phosphatidylinositol-4,5-bisphosphate binding (ortholog); INVOLVED IN cell surface receptor signaling pathway (ortholog); cellular response to bacterial lipopeptide (ortholog); cellular response to lipoteichoic acid (ortholog); PARTICIPATES IN Toll-like receptor signaNW_00493657259261935938621Squirrel93symbolgene, protein-coding, MODEL [RefSeq]
155244255tirapTropical Clawed Frogsymbolgene, null
626060130TirapTIR domain containing adaptor proteinENCODES a protein that exhibits identical protein binding (ortholog); molecular adaptor activity (ortholog); phosphatidylinositol-4,5-bisphosphate binding (ortholog); INVOLVED IN 3'-UTR-mediated mRNA stabilization (ortholog); cell surface receptor signaling pathway (ortholog); cellular response to bBlack Rat82symbolgene, protein-coding, MODEL [RefSeq]
13855494TIRAPTIR domain containing adaptor proteinENCODES a protein that exhibits phosphatidylinositol-4,5-bisphosphate binding (ortholog); INVOLVED IN cell surface receptor signaling pathway (ortholog); cellular response to bacterial lipopeptide (ortholog); cellular response to lipoteichoic acid (ortholog); PARTICIPATES IN Toll-like receptor signaPig92symbolgene, protein-coding, MODEL [RefSeq]
18926091TirapTIR domain containing adaptor proteinENCODES a protein that exhibits molecular adaptor activity (ortholog); phosphatidylinositol-4,5-bisphosphate binding (ortholog); protein kinase C binding (ortholog); INVOLVED IN 3'-UTR-mediated mRNA stabilization (ortholog); cell surface receptor signaling pathway (ortholog); cellular response to baNaked Mole-Rat89symbolgene, protein-coding, MODEL [RefSeq]
20865813TIRAPTIR domain containing adaptor proteinGreen Monkeysymbolgene, protein-coding
18543016TIRAPTIR domain containing adaptor proteinENCODES a protein that exhibits phosphatidylinositol-4,5-bisphosphate binding (ortholog); INVOLVED IN cell surface receptor signaling pathway (ortholog); cellular response to bacterial lipopeptide (ortholog); cellular response to lipoteichoic acid (ortholog); PARTICIPATES IN Toll-like receptor signaGreen Monkey93symbolgene, protein-coding, MODEL [RefSeq]
155255839tirap.LAfrican Clawed Frogsymbolgene, null
38660885TIRAP-AS1TIRAP antisense RNA 111126294296126304322Humansymbol , COSMIC , name , Human Proteome Mapgene, ncrna, VALIDATED [RefSeq]
16560486AP001318.1novel transcript, antisense to TIRAPHumannamegene, lncrna
16560563AP001318.2novel transcript, antisense to DCPS and TIRAPHumannamegene, lncrna
1317929TICAM2TIR domain containing adaptor molecule 2Enables molecular adaptor activity. Involved in several processes, including positive regulation of interleukin-18-mediated signaling pathway; regulation of cytokine production; and regulation of innate immune response. Located in endoplasmic reticulum; endosome; and phagocytic cup. Is active in end5115578496115602479Human133old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
2837468TMED7-TICAM2TMED7-TICAM2 readthroughThis locus represents naturally occurring read-through transcription between the neighboring transmembrane emp24 protein transport domain containing 7 (TMED7) and toll-like receptor adaptor molecule 2 (TICAM2) genes. Alternative splicing results in multiple transcript variants, one of which encodes 5115578496115626036Human91old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]