| 620674 | Taldo1 | transaldolase 1 | ENCODES a protein that exhibits carbohydrate binding; monosaccharide binding; transaldolase activity; INVOLVED IN fructose 6-phosphate metabolic process; glyceraldehyde-3-phosphate metabolic process; pentose-phosphate shunt; PARTICIPATES IN pentose phosphate pathway; pentose phosphate pathway - non- oxidative phase; ribose 5-phosphate isomerase deficiency pathway; ASSOCIATED WITH carbohydrate metabolic disorder (ortholog); cataract (ortholog); Chemical and Drug Induced Liver Injury (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleus (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dibromophenyl 2,4,5-tribromophenyl ether | 1 | 205923196 | 205933526 | Rat | 226 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 733188 | TALDO1 | transaldolase 1 | Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis. [provided by RefSeq, Jul 2008] | 11 | 747464 | 765012 | Human | 285 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 733189 | Taldo1 | transaldolase 1 | This gene encodes a key enzyme of the nonoxidative pentose phosphate pathway that provides ribose-5-phosphate for nucleic acid synthesis and nicotinamide adenine dinucleotide phosphate (NADPH) for lipid biosynthesis. The encoded protein is important for maintaining structure and function of mitochon dria. Studies in knockout mice identify that deficiency of this gene product is a cause of sperm dysmotility and male infertility. Deficiency of this protein has also been identified as a cause of hepatocarcinogenesis in mice. Two related pseudogenes have been identified on chromosome 10. [provided by RefSeq, Mar 2010] | 7 | 140972073 | 140982889 | Mouse | 238 | symbol , PhenoGen | gene, protein-coding, REVIEWED [RefSeq] |
| 8825728 | Taldo1 | transaldolase 1 | ENCODES a protein that exhibits carbohydrate binding (ortholog); identical protein binding (ortholog); monosaccharide binding (ortholog); INVOLVED IN fructose 6-phosphate metabolic process (ortholog); glyceraldehyde-3-phosphate metabolic process (ortholog); pentose-phosphate shunt (ortholog); PARTIC IPATES IN pentose phosphate pathway; pentose phosphate pathway - non-oxidative phase; ribose 5-phosphate isomerase deficiency pathway; ASSOCIATED WITH carbohydrate metabolic disorder (ortholog); cataract (ortholog); Chemical and Drug Induced Liver Injury (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleus (ortholog) | NW_004955476 | 11356601 | 11364573 | Chinchilla | 36 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11860704 | TALDO1 | transaldolase 1 | ENCODES a protein that exhibits carbohydrate binding (ortholog); identical protein binding (ortholog); monosaccharide binding (ortholog); INVOLVED IN fructose 6-phosphate metabolic process (ortholog); glyceraldehyde-3-phosphate metabolic process (ortholog); pentose-phosphate shunt (ortholog); PARTIC IPATES IN pentose phosphate pathway; pentose phosphate pathway - non-oxidative phase; ribose 5-phosphate isomerase deficiency pathway; ASSOCIATED WITH carbohydrate metabolic disorder (ortholog); cataract (ortholog); Chemical and Drug Induced Liver Injury (ortholog); FOUND IN nucleus (ortholog) | 11 | 764864 | 782548 | Bonobo | 46 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12365750 | TALDO1 | transaldolase 1 | ENCODES a protein that exhibits carbohydrate binding (ortholog); identical protein binding (ortholog); monosaccharide binding (ortholog); INVOLVED IN fructose 6-phosphate metabolic process (ortholog); glyceraldehyde-3-phosphate metabolic process (ortholog); pentose-phosphate shunt (ortholog); PARTIC IPATES IN pentose phosphate pathway; pentose phosphate pathway - non-oxidative phase; ribose 5-phosphate isomerase deficiency pathway; ASSOCIATED WITH carbohydrate metabolic disorder (ortholog); cataract (ortholog); Chemical and Drug Induced Liver Injury (ortholog); FOUND IN nucleus (ortholog) | 18 | 25764138 | 25772043 | Dog | 46 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12496000 | Taldo1 | transaldolase 1 | ENCODES a protein that exhibits carbohydrate binding (ortholog); identical protein binding (ortholog); monosaccharide binding (ortholog); INVOLVED IN fructose 6-phosphate metabolic process (ortholog); glyceraldehyde-3-phosphate metabolic process (ortholog); pentose-phosphate shunt (ortholog); PARTIC IPATES IN pentose phosphate pathway; pentose phosphate pathway - non-oxidative phase; ribose 5-phosphate isomerase deficiency pathway; ASSOCIATED WITH carbohydrate metabolic disorder (ortholog); cataract (ortholog); Chemical and Drug Induced Liver Injury (ortholog); FOUND IN nucleus (ortholog) | NW_004936888 | 531002 | 540194 | Squirrel | 46 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14233467 | TALDO1 | transaldolase 1 | ENCODES a protein that exhibits carbohydrate binding (ortholog); identical protein binding (ortholog); monosaccharide binding (ortholog); INVOLVED IN fructose 6-phosphate metabolic process (ortholog); glyceraldehyde-3-phosphate metabolic process (ortholog); pentose-phosphate shunt (ortholog); PARTIC IPATES IN pentose phosphate pathway; pentose phosphate pathway - non-oxidative phase; ribose 5-phosphate isomerase deficiency pathway; ASSOCIATED WITH carbohydrate metabolic disorder (ortholog); cataract (ortholog); Chemical and Drug Induced Liver Injury (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog) | | | | Pig | 51 | symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 625832368 | Taldo1 | transaldolase 1 | ENCODES a protein that exhibits carbohydrate binding (ortholog); identical protein binding (ortholog); monosaccharide binding (ortholog); INVOLVED IN fructose 6-phosphate metabolic process (ortholog); glyceraldehyde-3-phosphate metabolic process (ortholog); pentose-phosphate shunt (ortholog); PARTIC IPATES IN pentose phosphate pathway; pentose phosphate pathway - non-oxidative phase; ribose 5-phosphate isomerase deficiency pathway; ASSOCIATED WITH carbohydrate metabolic disorder (ortholog); cataract (ortholog); Chemical and Drug Induced Liver Injury (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleus (ortholog) | | | | Black Rat | 36 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18425381 | TALDO1 | transaldolase 1 | ENCODES a protein that exhibits carbohydrate binding (ortholog); identical protein binding (ortholog); monosaccharide binding (ortholog); INVOLVED IN fructose 6-phosphate metabolic process (ortholog); glyceraldehyde-3-phosphate metabolic process (ortholog); pentose-phosphate shunt (ortholog); PARTIC IPATES IN pentose phosphate pathway; pentose phosphate pathway - non-oxidative phase; ribose 5-phosphate isomerase deficiency pathway; ASSOCIATED WITH carbohydrate metabolic disorder (ortholog); cataract (ortholog); Chemical and Drug Induced Liver Injury (ortholog); FOUND IN nucleus (ortholog) | | | | Green Monkey | 46 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155240861 | taldo1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18925683 | Taldo1 | transaldolase 1 | ENCODES a protein that exhibits carbohydrate binding (ortholog); identical protein binding (ortholog); monosaccharide binding (ortholog); INVOLVED IN fructose 6-phosphate metabolic process (ortholog); glyceraldehyde-3-phosphate metabolic process (ortholog); pentose-phosphate shunt (ortholog); PARTIC IPATES IN pentose phosphate pathway; pentose phosphate pathway - non-oxidative phase; ribose 5-phosphate isomerase deficiency pathway; ASSOCIATED WITH carbohydrate metabolic disorder (ortholog); cataract (ortholog); Chemical and Drug Induced Liver Injury (ortholog); FOUND IN nucleus (ortholog) | | | | Naked Mole-Rat | 45 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155236057 | taldo1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 1589660 | Taldo1-ps1 | transaldolase 1, pseudogene 1 | | 9 | 8602524 | 8603542 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 41165622 | Taldo1-ps2 | transaldolase 1, pseudogene 2 | | 7 | 33393647 | 33395469 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 16556761 | AC099796.1 | transaldolase 1 (TALDO1) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 1353384 | TALDO1P1 | transaldolase 1 pseudogene 1 | | 1 | 54524824 | 54525097 | Human | | symbol , GTEx , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |