| 1348553 | TAF12 | TATA-box binding protein associated factor 12 | Control of transcription by RNA polymerase II involves the basal transcription machinery which is a collection of proteins. These proteins with RNA polymerase II, assemble into complexes which are modulated by transactivator proteins that bind to cis-regulatory elements located adjacent to the trans cription start site. Some modulators interact directly with the basal complex, whereas others may act as bridging proteins linking transactivators to the basal transcription factors. Some of these associated factors are weakly attached while others are tightly associated with TBP in the TFIID complex. Among the latter are the TAF proteins. Different TAFs are predicted to mediate the function of distinct transcriptional activators for a variety of gene promoters and RNA polymerases. TAF12 interacts directly with TBP as well as with TAF2I. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Sep 2008] | 1 | 28602850 | 28648269 | Human | 105 | symbol , old_gene_name , COSMIC , description , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1592841 | Taf12 | TATA-box binding protein associated factor 12 | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription factor binding (ortholog); RNA polymerase II general transcription initiation factor activity (ortholog); INVOLVED IN DNA-templated transcription initiation (ortholog); mRNA transcription by RNA polymerase II (ortholog ); positive regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN RNA polymerase I transcription pathway; RNA polymerase II transcription initiation pathway; FOUND IN nucleus (ortholog); SAGA complex (ortholog); transcription factor TFIID complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; C60 fullerene | 5 | 149756826 | 149772886 | Rat | 107 | symbol , old_gene_name , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1623219 | Taf12 | TATA-box binding protein associated factor 12 | Enables DNA binding activity. Predicted to be involved in RNA polymerase II preinitiation complex assembly; mRNA transcription by RNA polymerase II; and positive regulation of transcription initiation by RNA polymerase II. Located in nucleus. Part of SAGA complex. Is expressed in early conceptus; li mb; oocyte; and tail. Orthologous to human TAF12 (TATA-box binding protein associated factor 12). [provided by Alliance of Genome Resources, Jul 2025] | 4 | 132001667 | 132020640 | Mouse | 132 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 11778494 | TAF12 | TATA-box binding protein associated factor 12 | ENCODES a protein that exhibits DNA-binding transcription factor binding (ortholog); RNA polymerase II general transcription initiation factor activity (ortholog); transcription coactivator activity (ortholog); INVOLVED IN mRNA transcription by RNA polymerase II (ortholog); positive regulation of tr anscription by RNA polymerase II (ortholog); positive regulation of transcription initiation by RNA polymerase II (ortholog); PARTICIPATES IN RNA polymerase I transcription pathway; RNA polymerase II transcription initiation pathway; FOUND IN nucleus (ortholog); transcription factor TFTC complex (ortholog) | 1 | 27874675 | 27914672 | Bonobo | 36 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12218648 | TAF12 | TATA-box binding protein associated factor 12 | ENCODES a protein that exhibits DNA-binding transcription factor binding (ortholog); RNA polymerase II general transcription initiation factor activity (ortholog); transcription coactivator activity (ortholog); INVOLVED IN mRNA transcription by RNA polymerase II (ortholog); positive regulation of tr anscription by RNA polymerase II (ortholog); positive regulation of transcription initiation by RNA polymerase II (ortholog); PARTICIPATES IN RNA polymerase I transcription pathway; RNA polymerase II transcription initiation pathway; FOUND IN nucleus (ortholog); transcription factor TFTC complex (ortholog) | 2 | 71865274 | 71898236 | Dog | 36 | symbol , old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 12630061 | Taf12 | TATA-box binding protein associated factor 12 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor binding (inferred); protein heterodimerization activity (inferred); INVOLVED IN DNA-templated transcription (inferred); DNA-templated transcription initiation (inferred); mRNA transcription by RNA polymerase II (inferred); PARTICIPATES IN RNA polymerase I transcription pathway; RNA polymerase II transcription initiation pathway; FOUND IN nucleus (ortholog) | NW_004936474 | 12695508 | 12719384 | Squirrel | 41 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626118070 | Taf12 | TATA-box binding protein associated factor 12 | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription factor binding (ortholog); RNA polymerase II general transcription initiation factor activity (ortholog); INVOLVED IN DNA-templated transcription initiation (ortholog); mRNA transcription by RNA polymerase II (ortholog ); positive regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN RNA polymerase I transcription pathway; RNA polymerase II transcription initiation pathway; FOUND IN nucleus (ortholog); SAGA complex (ortholog); transcription factor TFIID complex (ortholog) | | | | Black Rat | 35 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 39131402 | TAF12 | TATA-box binding protein associated factor 12 | | | | | Chinchilla | | symbol | gene, protein-coding |
| 150657638 | TAF12 | | | | | | Dog | | symbol | gene, protein-coding |
| 18703596 | TAF12 | TATA-box binding protein associated factor 12 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor binding (inferred); protein heterodimerization activity (inferred); INVOLVED IN DNA-templated transcription (inferred); DNA-templated transcription initiation (inferred); mRNA transcription by RNA polymerase II (inferred); PARTICIPATES IN RNA polymerase I transcription pathway; RNA polymerase II transcription initiation pathway; FOUND IN nucleus (ortholog) | | | | Green Monkey | 41 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14223118 | TAF12 | TATA-box binding protein associated factor 12 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor binding (inferred); protein heterodimerization activity (inferred); INVOLVED IN DNA-templated transcription (inferred); DNA-templated transcription initiation (inferred); mRNA transcription by RNA polymerase II (inferred); PARTICIPATES IN RNA polymerase I transcription pathway; RNA polymerase II transcription initiation pathway; FOUND IN nucleus (ortholog) | | | | Pig | 43 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14388712 | TAF12 | | | | | | Yeast | | symbol | gene, null |
| 155238021 | taf12 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18901778 | Taf12 | TATA-box binding protein associated factor 12 | ENCODES a protein that exhibits DNA-binding transcription factor binding (ortholog); RNA polymerase II general transcription initiation factor activity (ortholog); transcription coactivator activity (ortholog); INVOLVED IN mRNA transcription by RNA polymerase II (ortholog); positive regulation of tr anscription by RNA polymerase II (ortholog); positive regulation of transcription initiation by RNA polymerase II (ortholog); PARTICIPATES IN RNA polymerase I transcription pathway; RNA polymerase II transcription initiation pathway; FOUND IN nucleus (ortholog); transcription factor TFTC complex (ortholog) | | | | Naked Mole-Rat | 38 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14388711 | Taf12 | | | | | | Fly | | symbol | gene, null |
| 155239496 | taf12.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155259672 | taf12.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 11564302 | TAF12-DT | TAF12 divergent transcript | Predicted to enable pre-mRNA 5'-splice site binding activity. Predicted to be involved in mRNA 5'-splice site recognition. Predicted to be part of U11 snRNP. [provided by Alliance of Genome Resources, Jul 2025] | 1 | 28643256 | 28648801 | Human | 3 | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 1597204 | Taf12-ps1 | TATA-box binding protein associated factor 12, pseudogene 1 | | 8 | 77163485 | 77164365 | Rat | | symbol , old_gene_name , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 12212416 | LOC608297 | TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa pseudogene | | 9 | 22209718 | 22210767 | Dog | | name | gene, pseudo, MODEL [RefSeq] |