| 727809 | Stk25 | serine/threonine kinase 25 | ENCODES a protein that exhibits protein homodimerization activity (ortholog); INVOLVED IN cellular response to oxidative stress (ortholog); establishment of Golgi localization (ortholog); establishment or maintenance of cell polarity (ortholog); FOUND IN Golgi membrane; cytoplasm (ortholog); FAR/SIN /STRIPAK complex (ortholog); INTERACTS WITH 3H-1,2-dithiole-3-thione; 4,4'-sulfonyldiphenol; bisphenol A | 9 | 101609218 | 101621458 | Rat | 114 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1342524 | STK25 | serine/threonine kinase 25 | This gene encodes a member of the germinal centre kinase III (GCK III) subfamily of the sterile 20 superfamily of kinases. The encoded enzyme plays a role in serine-threonine liver kinase B1 (LKB1) signaling pathway to regulate neuronal polarization and morphology of the Golgi apparatus. The protein is translocated from the Golgi apparatus to the nucleus in response to chemical anoxia and plays a role in regulation of cell death. A pseudogene associated with this gene is located on chromosome 18. Multiple alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2012] | 2 | 241492670 | 241509572 | Human | 123 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1550341 | Stk25 | serine/threonine kinase 25 (yeast) | Predicted to enable protein homodimerization activity and protein serine/threonine kinase activity. Acts upstream of or within several processes, including Golgi localization; positive regulation of axonogenesis; and protein phosphorylation. Predicted to be located in Golgi membrane. Predicted to be part of FAR/SIN/STRIPAK complex. Predicted to be active in Golgi apparatus. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human STK25 (serine/threonine kinase 25). [provided by Alliance of Genome Resources, Jul 2025] | 1 | 93548473 | 93581937 | Mouse | 114 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8720402 | Stk25 | serine/threonine kinase 25 | ENCODES a protein that exhibits protein homodimerization activity (ortholog); INVOLVED IN cellular response to oxidative stress (ortholog); establishment of Golgi localization (ortholog); establishment or maintenance of cell polarity (ortholog); FOUND IN cytoplasm (ortholog); FAR/SIN/STRIPAK complex (ortholog); Golgi apparatus (ortholog) | NW_004955542 | 268406 | 279323 | Chinchilla | 32 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11869093 | STK25 | serine/threonine kinase 25 | ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); metal ion binding (inferred); INVOLVED IN establishment or maintenance of cell polarity (ortholog); Golgi localization (ortholog); positive regulation of axonogenesis (ortholog); FOUND IN Golgi membrane (ortholog) | 2B | 128766408 | 128779939 | Bonobo | 53 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12316506 | STK25 | serine/threonine kinase 25 | ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); metal ion binding (inferred); INVOLVED IN establishment or maintenance of cell polarity (ortholog); Golgi localization (ortholog); positive regulation of axonogenesis (ortholog); FOUND IN Golgi membrane (ortholog) | 25 | 51425597 | 51434479 | Dog | 50 | symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 12437284 | Stk25 | serine/threonine kinase 25 | ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); metal ion binding (inferred); INVOLVED IN establishment or maintenance of cell polarity (ortholog); Golgi localization (ortholog); positive regulation of axonogenesis (ortholog); FOUND IN Golgi membrane (ortholog) | NW_004936745 | 420591 | 426890 | Squirrel | 49 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18921660 | Stk25 | serine/threonine kinase 25 | ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); metal ion binding (inferred); INVOLVED IN establishment or maintenance of cell polarity (ortholog); Golgi localization (ortholog); positive regulation of axonogenesis (ortholog); FOUND IN Golgi membrane (ortholog) | | | | Naked Mole-Rat | 49 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155252210 | stk25 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 14277376 | STK25 | serine/threonine kinase 25 | ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); metal ion binding (inferred); INVOLVED IN establishment or maintenance of cell polarity (ortholog); Golgi localization (ortholog); positive regulation of axonogenesis (ortholog); FOUND IN Golgi membrane (ortholog) | | | | Pig | 50 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18724265 | STK25 | serine/threonine kinase 25 | ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); metal ion binding (inferred); INVOLVED IN establishment or maintenance of cell polarity (ortholog); Golgi localization (ortholog); positive regulation of axonogenesis (ortholog); FOUND IN Golgi membrane (ortholog) | | | | Green Monkey | 53 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625883041 | Stk25 | serine/threonine kinase 25 | ENCODES a protein that exhibits protein homodimerization activity (ortholog); INVOLVED IN cellular response to oxidative stress (ortholog); establishment of Golgi localization (ortholog); establishment or maintenance of cell polarity (ortholog); FOUND IN cytoplasm (ortholog); FAR/SIN/STRIPAK complex (ortholog); Golgi apparatus (ortholog) | | | | Black Rat | 32 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155241999 | stk25.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155254957 | stk25.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 9586339 | STK25P1 | serine/threonine kinase 25 pseudogene 1 | | 18 | 12911217 | 12912264 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
