STK25 (serine/threonine kinase 25) - Rat Genome Database

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Gene: STK25 (serine/threonine kinase 25) Canis lupus familiaris
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Symbol: STK25
Name: serine/threonine kinase 25
RGD ID: 12316506
Description: ENCODES a protein that exhibits ATP binding (inferred); metal ion binding (inferred); protein homodimerization activity (inferred); INVOLVED IN axonogenesis (ortholog); establishment or maintenance of cell polarity (ortholog); Golgi localization (ortholog); ASSOCIATED WITH Bethlem Myopathy 1A (ortholog); chromosome 2q37 deletion syndrome (ortholog); D-2-hydroxyglutaric aciduria 1 (ortholog); FOUND IN Golgi membrane (ortholog)
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: serine/threonine-protein kinase 25
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12551,425,597 - 51,434,479 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2551,425,597 - 51,434,479 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2551,637,993 - 51,646,876 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02551,612,976 - 51,626,491 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2551,617,610 - 51,626,491 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12551,467,502 - 51,476,383 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02551,207,431 - 51,216,291 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02551,483,680 - 51,492,565 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:10964405   PMID:22301074  


Genomics

Comparative Map Data
STK25
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12551,425,597 - 51,434,479 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2551,425,597 - 51,434,479 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2551,637,993 - 51,646,876 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02551,612,976 - 51,626,491 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2551,617,610 - 51,626,491 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12551,467,502 - 51,476,383 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02551,207,431 - 51,216,291 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02551,483,680 - 51,492,565 (-)NCBIUU_Cfam_GSD_1.0
STK25
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382241,492,670 - 241,509,572 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2241,492,670 - 241,509,730 (-)EnsemblGRCh38hg38GRCh38
GRCh372242,432,085 - 242,448,987 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362242,083,105 - 242,096,707 (-)NCBINCBI36Build 36hg18NCBI36
Build 342242,154,422 - 242,168,024NCBI
Celera2236,104,013 - 236,117,625 (-)NCBICelera
Cytogenetic Map2q37.3NCBI
HuRef2234,189,627 - 234,204,482 (-)NCBIHuRef
CHM1_12242,440,093 - 242,454,954 (-)NCBICHM1_1
T2T-CHM13v2.02241,992,007 - 242,008,899 (-)NCBIT2T-CHM13v2.0
Stk25
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39193,548,473 - 93,581,937 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl193,547,473 - 93,586,381 (-)EnsemblGRCm39 Ensembl
GRCm38193,620,751 - 93,654,216 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl193,619,751 - 93,658,659 (-)EnsemblGRCm38mm10GRCm38
MGSCv37195,517,328 - 95,532,304 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36195,452,310 - 95,466,056 (-)NCBIMGSCv36mm8
Celera196,566,463 - 96,582,514 (-)NCBICelera
Cytogenetic Map1DNCBI
cM Map147.25NCBI
Stk25
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr89101,609,218 - 101,621,458 (-)NCBIGRCr8
mRatBN7.2994,161,834 - 94,174,095 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl994,161,836 - 94,174,244 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx9102,597,351 - 102,609,489 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09107,733,180 - 107,745,363 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09106,089,281 - 106,101,464 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.09100,767,578 - 100,779,715 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl9100,767,579 - 100,779,715 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.09100,420,925 - 100,433,656 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4992,907,764 - 92,919,903 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1993,112,533 - 93,124,672 (-)NCBI
Celera991,695,836 - 91,707,760 (-)NCBICelera
Cytogenetic Map9q36NCBI
Stk25
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955542272,715 - 280,110 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955542268,406 - 279,323 (+)NCBIChiLan1.0ChiLan1.0
STK25
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213144,198,120 - 144,211,568 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B144,213,015 - 144,226,459 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B128,766,408 - 128,779,939 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B247,560,624 - 247,574,249 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B247,560,624 - 247,574,249 (-)Ensemblpanpan1.1panPan2
Stk25
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303192,792,530 - 192,798,829 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936745420,073 - 426,393 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936745420,591 - 426,890 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STK25
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15140,144,336 - 140,154,366 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115140,144,334 - 140,154,361 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215154,683,027 - 154,693,144 (-)NCBISscrofa10.2Sscrofa10.2susScr3
STK25
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110127,571,024 - 127,580,628 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10127,571,665 - 127,580,071 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604071,742,570 - 71,772,625 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Stk25
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248475,511,007 - 5,530,764 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248475,511,590 - 5,530,773 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in STK25
156 total Variants

Sequence


Ensembl Acc Id: ENSCAFT00000009084   ⟹   ENSCAFP00000008426
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2551,425,597 - 51,434,479 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000062594   ⟹   ENSCAFP00000047345
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2551,425,597 - 51,433,946 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000089654   ⟹   ENSCAFP00000046057
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2551,425,597 - 51,434,479 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845041526   ⟹   ENSCAFP00845032556
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2551,617,610 - 51,626,491 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845041600   ⟹   ENSCAFP00845032620
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2551,617,610 - 51,625,958 (-)Ensembl
RefSeq Acc Id: NM_001286859   ⟹   NP_001273788
RefSeq Status: VALIDATED
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12551,425,597 - 51,434,479 (-)NCBI
Dog10K_Boxer_Tasha2551,637,993 - 51,646,876 (-)NCBI
ROS_Cfam_1.02551,617,610 - 51,626,491 (-)NCBI
UMICH_Zoey_3.12551,467,502 - 51,476,383 (-)NCBI
UNSW_CanFamBas_1.02551,207,431 - 51,216,291 (-)NCBI
UU_Cfam_GSD_1.02551,483,680 - 51,492,565 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038434509   ⟹   XP_038290437
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02551,616,682 - 51,626,399 (-)NCBI
RefSeq Acc Id: XM_038434510   ⟹   XP_038290438
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02551,612,976 - 51,625,545 (-)NCBI
RefSeq Acc Id: NP_001273788   ⟸   NM_001286859
- UniProtKB: A0A8C0LGT0 (UniProtKB/TrEMBL),   A0A8C0Z6K6 (UniProtKB/TrEMBL),   A0A8I3PJR0 (UniProtKB/TrEMBL),   A0A8C0TU82 (UniProtKB/TrEMBL),   A0A8P0NW76 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000008426   ⟸   ENSCAFT00000009084
Ensembl Acc Id: ENSCAFP00000047345   ⟸   ENSCAFT00000062594
Ensembl Acc Id: ENSCAFP00000046057   ⟸   ENSCAFT00000089654
RefSeq Acc Id: XP_038290438   ⟸   XM_038434510
- Peptide Label: isoform X2
- UniProtKB: A0A8C0TVV5 (UniProtKB/TrEMBL),   A0A8I3PF96 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038290437   ⟸   XM_038434509
- Peptide Label: isoform X1
- UniProtKB: A0A8C0LGT0 (UniProtKB/TrEMBL),   A0A8C0Z6K6 (UniProtKB/TrEMBL),   A0A8I3PJR0 (UniProtKB/TrEMBL),   A0A8C0TU82 (UniProtKB/TrEMBL),   A0A8P0NW76 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845032620   ⟸   ENSCAFT00845041600
Ensembl Acc Id: ENSCAFP00845032556   ⟸   ENSCAFT00845041526
Protein Domains
Protein kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000013032 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030025317 UniProtKB/TrEMBL
  ENSCAFG00040024811 UniProtKB/TrEMBL
  ENSCAFG00845023492 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000009084.5 UniProtKB/TrEMBL
  ENSCAFT00000061363.2 UniProtKB/TrEMBL
  ENSCAFT00000062594.2 UniProtKB/TrEMBL
  ENSCAFT00000089654.2 UniProtKB/TrEMBL
  ENSCAFT00030046819.1 UniProtKB/TrEMBL
  ENSCAFT00030046841.1 UniProtKB/TrEMBL
  ENSCAFT00030046846.1 UniProtKB/TrEMBL
  ENSCAFT00030046871.1 UniProtKB/TrEMBL
  ENSCAFT00040046291.1 UniProtKB/TrEMBL
  ENSCAFT00040046329.1 UniProtKB/TrEMBL
  ENSCAFT00040046360.1 UniProtKB/TrEMBL
  ENSCAFT00845041526 ENTREZGENE
  ENSCAFT00845041526.1 UniProtKB/TrEMBL
  ENSCAFT00845041600.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.12.70 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Kinase-like_dom_sf UniProtKB/TrEMBL
  PDC10_dimerisation_sf UniProtKB/TrEMBL
  PDCD10_N UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  STE20/SPS1-PAK UniProtKB/TrEMBL
  STK_STK25 UniProtKB/TrEMBL
KEGG Report cfa:403531 UniProtKB/TrEMBL
NCBI Gene STK25 ENTREZGENE
PANTHER SERINE/THREONINE-PROTEIN KINASE 25 UniProtKB/TrEMBL
  STERILE20-LIKE KINASE, ISOFORM B-RELATED UniProtKB/TrEMBL
Pfam PDCD10_N UniProtKB/TrEMBL
  Pkinase UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt A0A8C0LGT0 ENTREZGENE
  A0A8C0PFL6_CANLF UniProtKB/TrEMBL
  A0A8C0TU82 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0TVV5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0Z6K6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PF96 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PJR0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0NW76 ENTREZGENE
  A0A8P0T8R1_CANLF UniProtKB/TrEMBL
UniProt Secondary A0A8P0NW76 UniProtKB/TrEMBL
VGNC ID VGNC:46909 ENTREZGENE