Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Genes search result for All species
(View Results for all Objects and Ontologies)

17 records found for search term Spry4
Refine Term:
Sort By:
           Export CSV TAB Print

RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
1305324Spry4sprouty RTK signaling antagonist 4ENCODES a protein that exhibits protein kinase inhibitor activity (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); negative regulation of MAP kinase activity (ortholog); negative regulation of substrate adhesion-dependent cell spreading (ortholog); PARTICIPATES IN 183068763330702546Rat186symbol , PhenoGengene, protein-coding, PROVISIONAL [RefSeq]
1313286SPRY4sprouty RTK signaling antagonist 4This gene encodes a member of a family of cysteine- and proline-rich proteins. The encoded protein is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. Activity of this protein impairs the formation of active GTP-RAS. Nucleotide variation in this gene5142310430142325021Human276symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1313287Spry4sprouty RTK signaling antagonist 4Predicted to enable protein kinase inhibitor activity. Acts upstream of or within cellular response to leukemia inhibitory factor and negative regulation of MAP kinase activity. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Is expressed in several structures, including ali183871930038734400Mouse225symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
9023168Spry4sprouty RTK signaling antagonist 4ENCODES a protein that exhibits protein kinase inhibitor activity (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); negative regulation of MAP kinase activity (ortholog); negative regulation of substrate adhesion-dependent cell spreading (ortholog); ASSOCIATED WITH NW_0049554151148943911504247Chinchilla22symbolgene, protein-coding, MODEL [RefSeq]
11920626SPRY4sprouty RTK signaling antagonist 4ENCODES a protein that exhibits protein kinase inhibitor activity (inferred); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); negative regulation of MAP kinase activity (ortholog); ASSOCIATED WITH acute myeloid leukemia (ortholog); amenorrhea (ortholog); disorder of sexual de5137667280137683578Bonobo28symbolgene, protein-coding, MODEL [RefSeq]
12246313SPRY4sprouty RTK signaling antagonist 4ENCODES a protein that exhibits protein kinase inhibitor activity (inferred); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); negative regulation of MAP kinase activity (ortholog); ASSOCIATED WITH acute myeloid leukemia (ortholog); amenorrhea (ortholog); disorder of sexual de23719989037213710Dog29symbolgene, protein-coding, MODEL [RefSeq]
12636953Spry4sprouty RTK signaling antagonist 4ENCODES a protein that exhibits protein kinase inhibitor activity (inferred); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); negative regulation of MAP kinase activity (ortholog); ASSOCIATED WITH acute myeloid leukemia (ortholog); amenorrhea (ortholog); disorder of sexual deNW_0049365041190766711922487Squirrel28symbolgene, protein-coding, MODEL [RefSeq]
626130670Spry4sprouty RTK signaling antagonist 4ENCODES a protein that exhibits protein kinase inhibitor activity (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); negative regulation of MAP kinase activity (ortholog); negative regulation of substrate adhesion-dependent cell spreading (ortholog); ASSOCIATED WITH Black Rat22symbolgene, protein-coding, MODEL [RefSeq]
18912988Spry4sprouty RTK signaling antagonist 4ENCODES a protein that exhibits protein kinase inhibitor activity (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); negative regulation of MAP kinase activity (ortholog); negative regulation of substrate adhesion-dependent cell spreading (ortholog); ASSOCIATED WITH Naked Mole-Rat27symbolgene, protein-coding, MODEL [RefSeq]
20866865SPRY4sprouty RTK signaling antagonist 4Green Monkeysymbolgene, protein-coding
14124124SPRY4sprouty RTK signaling antagonist 4ENCODES a protein that exhibits protein kinase inhibitor activity (inferred); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); negative regulation of MAP kinase activity (ortholog); ASSOCIATED WITH acute myeloid leukemia (ortholog); amenorrhea (ortholog); disorder of sexual dePig29symbolgene, protein-coding, MODEL [RefSeq]
18474456SPRY4sprouty RTK signaling antagonist 4ENCODES a protein that exhibits protein kinase inhibitor activity (inferred); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); negative regulation of MAP kinase activity (ortholog); ASSOCIATED WITH acute myeloid leukemia (ortholog); amenorrhea (ortholog); disorder of sexual deGreen Monkey28symbolgene, protein-coding, MODEL [RefSeq]
155239577spry4Tropical Clawed Frogsymbolgene, null
155231103spry4.LAfrican Clawed Frogsymbolgene, null
155234163spry4.SAfrican Clawed Frogsymbolgene, null
12903136SPRY4-AS1SPRY4 antisense RNA 1INTERACTS WITH mono(2-ethyl-5-hydroxyhexyl) phthalate; mono(2-ethyl-5-oxohexyl) phthalate; mono(2-ethylhexyl) phthalate5142325293142464054Human9symbol , COSMIC , name , Human Proteome Mapgene, ncrna, VALIDATED [RefSeq]
5135340SPRY4-IT1SPRY4 intronic transcript 1This gene produces a non-coding RNA that is upregulated in several different tumors, including melanoma and breast and prostate cancer cells. This transcript may mediate cell growth, proliferation, and apoptosis. It regulates levels of lipin 2, and therefore may be involved in lipid biosynthesis. Th5142317620142318322Human2symbol , GTEx , COSMIC , name , description , Human Proteome Mapgene, ncrna, REVIEWED [RefSeq]