| 1307619 | Sp8 | Sp8 transcription factor | ENCODES a protein that exhibits sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN dorsal/ventral pattern formation (ortholog); embryonic limb morphogenesis (ortholog); proximal/distal pattern formation (ortholog); FOUND IN nucleus (inferred); INTERACTS WITH bisphenol A; trichloro ethene; 3,3',5,5'-tetrabromobisphenol A (ortholog) | 6 | 145959219 | 145961824 | Rat | 69 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1316919 | SP8 | Sp8 transcription factor | The protein encoded by this gene is an SP family transcription factor that in mouse has been shown to be essential for proper limb development. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011] | 7 | 20782279 | 20786886 | Human | 71 | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1316920 | Sp8 | trans-acting transcription factor 8 | Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in embryonic limb morphogenesis. Acts upstream of or within dorsal/ventral pattern formation and proximal/distal patt ern formation. Predicted to be located in nucleus. Is expressed in several structures, including branchial arch; embryo ectoderm; limb bud; nose; and primitive streak. Orthologous to human SP8 (Sp8 transcription factor). [provided by Alliance of Genome Resources, Jul 2025] | 12 | 118809968 | 118816313 | Mouse | 176 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8965806 | Sp8 | Sp8 transcription factor | ENCODES a protein that exhibits sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN dorsal/ventral pattern formation (ortholog); embryonic limb morphogenesis (ortholog); proximal/distal pattern formation (ortholog) | NW_004955410 | 23401888 | 23404654 | Chinchilla | 5 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 11968101 | SP8 | Sp8 transcription factor | ENCODES a protein that exhibits sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN dorsal/ventral pattern formation (ortholog); embryonic limb morphogenesis (ortholog); proximal/distal pattern formation (ortholog) | 7 | 21456649 | 21463844 | Bonobo | 5 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12267786 | SP8 | Sp8 transcription factor | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); sequence-specific double-stranded DNA binding (inferred); INVOLVED IN dorsal/ventral pattern formation (ortholog); embryonic limb morphogenesis (ortholog); proximal/distal pattern formation (ortholog); FOUND IN nuc leus (inferred) | 14 | 34786296 | 34791495 | Dog | 14 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12730998 | Sp8 | Sp8 transcription factor | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); metal ion binding (inferred); INVOLVED IN dorsal/ventral pattern formation (ortholog); embryonic limb morphogenesis (ortholog); proximal/distal pattern formation (ortholog); FOUND IN nucleus (inferred) | NW_004936546 | 6744209 | 6746797 | Squirrel | 13 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 284372890 | sp8 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 13852717 | SP8 | Sp8 transcription factor | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); sequence-specific double-stranded DNA binding (inferred); INVOLVED IN dorsal/ventral pattern formation (ortholog); embryonic limb morphogenesis (ortholog); proximal/distal pattern formation (ortholog); FOUND IN nuc leus (inferred) | | | | Pig | 14 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18916456 | Sp8 | Sp8 transcription factor | ENCODES a protein that exhibits sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN dorsal/ventral pattern formation (ortholog); embryonic limb morphogenesis (ortholog); proximal/distal pattern formation (ortholog); FOUND IN nucleus (inferred) | | | | Naked Mole-Rat | 13 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18721072 | SP8 | Sp8 transcription factor | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); metal ion binding (inferred); INVOLVED IN dorsal/ventral pattern formation (ortholog); embryonic limb morphogenesis (ortholog); proximal/distal pattern formation (ortholog); FOUND IN nucleus (inferred) | | | | Green Monkey | 13 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 625981968 | Sp8 | Sp8 transcription factor | ENCODES a protein that exhibits sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN dorsal/ventral pattern formation (ortholog); embryonic limb morphogenesis (ortholog); proximal/distal pattern formation (ortholog) | | | | Black Rat | 5 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 285112457 | sp8.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 288057326 | sp8.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 1354475 | TEX101 | testis expressed 101 | Predicted to be involved in binding activity of sperm to zona pellucida; flagellated sperm motility; and regulation of flagellated sperm motility. Predicted to be located in acrosomal vesicle; extracellular region; and plasma membrane. Predicted to be active in plasma membrane raft. [provided by All iance of Genome Resources, Jul 2025] | 19 | 43388611 | 43418597 | Human | 58 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1352349 | CLDN2 | claudin 2 | This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This pro tein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.[provided by RefSeq, Jan 2010] | X | 106900164 | 106930861 | Human | 222 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 14164907 | OPALIN | oligodendrocytic myelin paranodal and inner loop protein | INVOLVED IN regulation of oligodendrocyte differentiation (ortholog); FOUND IN cell-cell contact zone (ortholog); plasma membrane (ortholog) | | | | Pig | 9 | old_gene_name , old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |