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Gene: Sp8 (trans-acting transcription factor 8) Mus musculus
Symbol: Sp8
Name: trans-acting transcription factor 8
Description: Predicted to have DNA binding activity and DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in dorsal/ventral pattern formation; embryonic limb morphogenesis; and proximal/distal pattern formation. Predicted to localize to the nucleus. Is expressed in several structures, including 1st branchial arch; brain; embryo ectoderm; inner ear; and nose. Orthologous to human SP8 (Sp8 transcription factor); INTERACTS WITH 3,3',5,5'-tetrabromobisphenol A; 3,4-methylenedioxymethamphetamine; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: D930049B17Rik; mBtd; MGC105193; transcription factor Sp8
Homo sapiens (human) : SP8 (Sp8 transcription factor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Sp8 (Sp8 transcription factor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sp8 (Sp8 transcription factor)
Pan paniscus (bonobo/pygmy chimpanzee) : SP8 (Sp8 transcription factor)
Canis lupus familiaris (dog) : SP8 (Sp8 transcription factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sp8 (Sp8 transcription factor)
Sus scrofa (pig) : SP8 (Sp8 transcription factor)
Chlorocebus sabaeus (African green monkey) : SP8 (Sp8 transcription factor)
Heterocephalus glaber (naked mole-rat) : Sp8 (Sp8 transcription factor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl12118,846,329 - 118,852,576 (+)EnsemblGRCm38mm10GRCm38
GRCm3812118,846,288 - 118,852,578 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3712120,084,802 - 120,091,051 (+)NCBIGRCm37mm9NCBIm37
MGSCv3612119,291,658 - 119,296,678 (+)NCBImm8
MGSCv3612113,073,063 - 113,078,083 (+)NCBImm8
Cytogenetic Map12 F2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Sp8
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1316920
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-02-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.