SP8 (Sp8 transcription factor) - Rat Genome Database

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Gene: SP8 (Sp8 transcription factor) Canis lupus familiaris
Analyze
Symbol: SP8
Name: Sp8 transcription factor
RGD ID: 12267786
Description: ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); RNA polymerase II cis-regulatory region sequence-specific DNA binding (inferred); INVOLVED IN dorsal/ventral pattern formation (ortholog); embryonic limb morphogenesis (ortholog); proximal/distal pattern formation (ortholog); ASSOCIATED WITH genetic disease (ortholog); pleomorphic xanthoastrocytoma (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: transcription factor Sp8
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11434,786,296 - 34,791,495 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1434,331,138 - 34,335,254 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01434,714,812 - 34,718,933 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1434,715,197 - 34,719,048 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11434,834,295 - 34,838,397 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01434,534,781 - 34,538,889 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01434,869,616 - 34,873,731 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
SP8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11434,786,296 - 34,791,495 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1434,331,138 - 34,335,254 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01434,714,812 - 34,718,933 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1434,715,197 - 34,719,048 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11434,834,295 - 34,838,397 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01434,534,781 - 34,538,889 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01434,869,616 - 34,873,731 (-)NCBIUU_Cfam_GSD_1.0
SP8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38720,782,279 - 20,786,886 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl720,782,279 - 20,786,886 (-)EnsemblGRCh38hg38GRCh38
GRCh37720,821,899 - 20,826,505 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36720,788,426 - 20,793,030 (-)NCBINCBI36Build 36hg18NCBI36
Build 34720,595,140 - 20,599,745NCBI
Celera720,807,385 - 20,812,013 (-)NCBICelera
Cytogenetic Map7p21.1NCBI
HuRef720,706,730 - 20,711,356 (-)NCBIHuRef
CHM1_1720,822,403 - 20,827,032 (-)NCBICHM1_1
T2T-CHM13v2.0720,918,318 - 20,922,938 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2720,873,227 - 20,877,855 (-)NCBI
Sp8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912118,809,968 - 118,816,313 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12118,810,064 - 118,816,311 (+)EnsemblGRCm39 Ensembl
GRCm3812118,846,288 - 118,852,578 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12118,846,329 - 118,852,576 (+)EnsemblGRCm38mm10GRCm38
MGSCv3712120,084,802 - 120,091,051 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612113,073,063 - 113,078,083 (+)NCBIMGSCv36mm8
MGSCv3612119,291,658 - 119,296,678 (+)NCBIMGSCv36mm8
Cytogenetic Map12F2NCBI
cM Map1263.48NCBI
Sp8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86145,959,219 - 145,961,824 (+)NCBIGRCr8
mRatBN7.26139,816,258 - 139,818,865 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6139,814,819 - 139,823,168 (+)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl6139,814,819 - 139,823,168 (+)NCBImRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6143,268,110 - 143,270,717 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06139,885,580 - 139,888,181 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06140,432,005 - 140,434,612 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06146,784,915 - 146,789,439 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6146,784,915 - 146,787,518 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06155,693,431 - 155,696,034 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46146,169,226 - 146,171,829 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16146,176,505 - 146,177,966 (+)NCBI
Celera6137,463,142 - 137,465,745 (+)NCBICelera
Cytogenetic Map6q33NCBI
Sp8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541023,401,971 - 23,403,423 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541023,401,888 - 23,404,654 (-)NCBIChiLan1.0ChiLan1.0
SP8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2625,635,414 - 25,642,609 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1773,960,141 - 73,967,336 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0721,456,649 - 21,463,844 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1720,772,300 - 20,778,071 (-)NCBIpanpan1.1PanPan1.1panPan2
Sp8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511879,066,307 - 79,071,700 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365466,744,209 - 6,746,797 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365466,744,209 - 6,746,797 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SP8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl989,764,764 - 89,767,393 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1989,764,671 - 89,767,428 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2999,261,088 - 99,267,025 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SP8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12137,453,667 - 37,467,434 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2137,462,097 - 37,464,588 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604267,109,219 - 67,114,713 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sp8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247399,793,290 - 9,795,684 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247399,792,963 - 9,795,697 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SP8
71 total Variants

Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_014118906 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038442229 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038442232 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038495289 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038495290 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038556385 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038556386 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038620309 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038620310 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038685987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038685988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000158 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000208 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00845013635   ⟹   ENSCAFP00845010588
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1434,715,197 - 34,719,048 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845013658   ⟹   ENSCAFP00845010605
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1434,715,197 - 34,717,916 (-)Ensembl
RefSeq Acc Id: XM_038442229   ⟹   XP_038298157
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1434,331,138 - 34,335,254 (-)NCBI
RefSeq Acc Id: XM_038442232   ⟹   XP_038298160
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1434,331,138 - 34,334,227 (-)NCBI
RefSeq Acc Id: XM_038495289   ⟹   XP_038351217
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11434,834,295 - 34,838,397 (-)NCBI
RefSeq Acc Id: XM_038495290   ⟹   XP_038351218
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11434,834,295 - 34,837,379 (-)NCBI
RefSeq Acc Id: XM_038556385   ⟹   XP_038412313
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01434,869,616 - 34,873,731 (-)NCBI
RefSeq Acc Id: XM_038556386   ⟹   XP_038412314
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01434,869,616 - 34,872,711 (-)NCBI
RefSeq Acc Id: XM_038620309   ⟹   XP_038476237
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01434,534,781 - 34,538,889 (-)NCBI
RefSeq Acc Id: XM_038620310   ⟹   XP_038476238
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01434,534,781 - 34,537,867 (-)NCBI
RefSeq Acc Id: XM_038685987   ⟹   XP_038541915
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01434,714,812 - 34,718,933 (-)NCBI
RefSeq Acc Id: XM_038685988   ⟹   XP_038541916
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01434,714,812 - 34,717,906 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_038351217   ⟸   XM_038495289
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038351218   ⟸   XM_038495290
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038476237   ⟸   XM_038620309
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038476238   ⟸   XM_038620310
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038541915   ⟸   XM_038685987
- Peptide Label: isoform X1
- UniProtKB: A0A8I3MXG7 (UniProtKB/TrEMBL),   A0A8P0TJN0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038541916   ⟸   XM_038685988
- Peptide Label: isoform X2
- UniProtKB: A0A8C0P7F0 (UniProtKB/TrEMBL),   A0A8I3RU43 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038298157   ⟸   XM_038442229
- Peptide Label: isoform X1
- UniProtKB: A0A8I3MXG7 (UniProtKB/TrEMBL),   A0A8P0TJN0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038298160   ⟸   XM_038442232
- Peptide Label: isoform X2
- UniProtKB: A0A8C0P7F0 (UniProtKB/TrEMBL),   A0A8I3RU43 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038412313   ⟸   XM_038556385
- Peptide Label: isoform X1
- UniProtKB: A0A8I3MXG7 (UniProtKB/TrEMBL),   A0A8P0TJN0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038412314   ⟸   XM_038556386
- Peptide Label: isoform X2
- UniProtKB: A0A8C0P7F0 (UniProtKB/TrEMBL),   A0A8I3RU43 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845010588   ⟸   ENSCAFT00845013635
RefSeq Acc Id: ENSCAFP00845010605   ⟸   ENSCAFT00845013658
Protein Domains
C2H2-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000045908 UniProtKB/TrEMBL
  ENSCAFG00030022501 UniProtKB/TrEMBL
  ENSCAFG00040005409 UniProtKB/TrEMBL
  ENSCAFG00845007758 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000086956.2 UniProtKB/TrEMBL
  ENSCAFT00000097311.1 UniProtKB/TrEMBL
  ENSCAFT00030041334.1 UniProtKB/TrEMBL
  ENSCAFT00040010154.1 UniProtKB/TrEMBL
  ENSCAFT00845013635 ENTREZGENE
  ENSCAFT00845013635.1 UniProtKB/TrEMBL
  ENSCAFT00845013658 ENTREZGENE
  ENSCAFT00845013658.1 UniProtKB/TrEMBL
Gene3D-CATH Classic Zinc Finger UniProtKB/TrEMBL
InterPro Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
NCBI Gene SP8 ENTREZGENE
PANTHER KRUEPPEL-LIKE TRANSCRIPTION FACTOR UniProtKB/TrEMBL
  TRANSCRIPTION FACTOR SP8 UniProtKB/TrEMBL
Pfam zf-C2H2 UniProtKB/TrEMBL
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
SMART ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF57667 UniProtKB/TrEMBL
UniProt A0A8C0P7F0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MXG7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3RU43 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0TJN0 ENTREZGENE, UniProtKB/TrEMBL