| 708439 | Srcin1 | SRC kinase signaling inhibitor 1 | ENCODES a protein that exhibits protein domain specific binding; protein kinase binding (ortholog); INVOLVED IN behavioral response to cocaine; conditioned place preference; negative regulation of protein secretion; ASSOCIATED WITH cocaine dependence; Cocaine-Related Disorders (ortholog); FOUND IN a ctin cytoskeleton; axon; dendrite; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; acetamide | 10 | 82999295 | 83066359 | Rat | 145 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 734075 | Srcin1 | SRC kinase signaling inhibitor 1 | Predicted to enable protein domain specific binding activity and protein kinase binding activity. Involved in regulation of synapse assembly. Acts upstream of or within negative regulation of cell adhesion. Located in postsynaptic density. Is active in glutamatergic synapse and presynapse. Is expres sed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and respiratory system. Orthologous to human SRCIN1 (SRC kinase signaling inhibitor 1). [provided by Alliance of Genome Resources, Jul 2025] | 11 | 97400166 | 97466059 | Mouse | 167 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1606779 | SRCIN1 | SRC kinase signaling inhibitor 1 | Enables protein kinase binding activity. Involved in several processes, including postsynaptic actin cytoskeleton organization; regulation of protein tyrosine kinase activity; and substrate adhesion-dependent cell spreading. Located in actin cytoskeleton and cytoplasm. Is active in glutamatergic syn apse. [provided by Alliance of Genome Resources, Jul 2025] | 17 | 38530031 | 38607025 | Human | 134 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1563437 | Etl4 | enhancer trap locus 4 | INVOLVED IN embryonic skeletal system development (ortholog); FOUND IN centrosome (ortholog); cytoplasm (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 17 | 87749486 | 88213158 | Rat | 117 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1359268 | Snip1 | Smad nuclear interacting protein 1 | ENCODES a protein that exhibits transcription regulator inhibitor activity (ortholog); INVOLVED IN miRNA processing (ortholog); mRNA splicing, via spliceosome (ortholog); negative regulation of canonical NF-kappaB signal transduction (ortholog); ASSOCIATED WITH ARTERIAL DISSECTION (ortholog); benign epilepsy with centrotemporal spikes (ortholog); Psychomotor Retardation, Epilepsy, and Craniofacial Dysmorphism (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); U2-type precatalytic spliceosome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; gentamycin | 5 | 142613028 | 142620502 | Rat | 103 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1550612 | Snip1 | Smad nuclear interacting protein 1 | Enables transcription regulator inhibitor activity. Involved in negative regulation of canonical NF-kappaB signal transduction. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Is active in nucleus. Is expressed in several structures, including branchial arch; ce rebral cortex; gut epithelium; metanephros; and sensory organ. Orthologous to human SNIP1 (Smad nuclear interacting protein 1). [provided by Alliance of Genome Resources, Jul 2025] | 4 | 124960465 | 124967836 | Mouse | 121 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1605941 | SNIP1 | Smad nuclear interacting protein 1 | This gene encodes a protein that contains a coiled-coil motif and C-terminal forkhead-associated (FHA) domain. The encoded protein functions as a transcriptional coactivator that increases c-Myc activity and inhibits transforming growth factor beta (TGF-beta) and nuclear factor kappa-B (NF-kB) signa ling. The encoded protein also regulates the stability of cyclin D1 mRNA, and may play a role in cell proliferation and cancer progression. Mutations in this gene are a cause of psychomotor retardation, epilepsy, and craniofacial dysmorphism (PMRED). [provided by RefSeq, Mar 2012] | 1 | 37534449 | 37554293 | Human | 143 | symbol , old_gene_name , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 9034594 | Snip1 | Smad nuclear interacting protein 1 | ENCODES a protein that exhibits transcription regulator inhibitor activity (ortholog); INVOLVED IN miRNA processing (ortholog); mRNA splicing, via spliceosome (ortholog); negative regulation of canonical NF-kappaB signal transduction (ortholog); ASSOCIATED WITH ARTERIAL DISSECTION (ortholog); benign epilepsy with centrotemporal spikes (ortholog); Psychomotor Retardation, Epilepsy, and Craniofacial Dysmorphism (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); spliceosomal complex (ortholog) | NW_004955452 | 15352080 | 15365545 | Chinchilla | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11735707 | SNIP1 | Smad nuclear interacting protein 1 | ENCODES a protein that exhibits transcription regulator inhibitor activity (inferred); INVOLVED IN miRNA processing (inferred); mRNA processing (inferred); mRNA splicing, via spliceosome (inferred); ASSOCIATED WITH ARTERIAL DISSECTION (ortholog); benign epilepsy with centrotemporal spikes (ortholog) ; Psychomotor Retardation, Epilepsy, and Craniofacial Dysmorphism (ortholog); FOUND IN nucleoplasm (inferred); nucleus (inferred); spliceosomal complex (inferred) | 1 | 36807488 | 36827347 | Bonobo | 32 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12347864 | SNIP1 | Smad nuclear interacting protein 1 | ENCODES a protein that exhibits transcription regulator inhibitor activity (inferred); INVOLVED IN miRNA processing (inferred); mRNA processing (inferred); mRNA splicing, via spliceosome (inferred); ASSOCIATED WITH ARTERIAL DISSECTION (ortholog); benign epilepsy with centrotemporal spikes (ortholog) ; Psychomotor Retardation, Epilepsy, and Craniofacial Dysmorphism (ortholog); FOUND IN nucleoplasm (inferred); nucleus (inferred); spliceosomal complex (inferred) | 15 | 4924035 | 4934565 | Dog | 35 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12714453 | Snip1 | Smad nuclear interacting protein 1 | ENCODES a protein that exhibits transcription regulator inhibitor activity (inferred); INVOLVED IN miRNA processing (inferred); mRNA processing (inferred); mRNA splicing, via spliceosome (inferred); ASSOCIATED WITH ARTERIAL DISSECTION (ortholog); benign epilepsy with centrotemporal spikes (ortholog) ; Psychomotor Retardation, Epilepsy, and Craniofacial Dysmorphism (ortholog); FOUND IN nucleoplasm (inferred); nucleus (inferred); spliceosomal complex (inferred) | NW_004936474 | 19760653 | 19778224 | Squirrel | 32 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155240467 | snip1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18924886 | Snip1 | Smad nuclear interacting protein 1 | ENCODES a protein that exhibits transcription regulator inhibitor activity (ortholog); INVOLVED IN miRNA processing (ortholog); mRNA splicing, via spliceosome (ortholog); negative regulation of canonical NF-kappaB signal transduction (ortholog); ASSOCIATED WITH ARTERIAL DISSECTION (ortholog); benign epilepsy with centrotemporal spikes (ortholog); Psychomotor Retardation, Epilepsy, and Craniofacial Dysmorphism (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); U12-type catalytic step 2 spliceosome (ortholog) | | | | Naked Mole-Rat | 33 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 20865683 | SNIP1 | Smad nuclear interacting protein 1 | | | | | Green Monkey | | symbol | gene, protein-coding |
| 13863276 | SNIP1 | Smad nuclear interacting protein 1 | ENCODES a protein that exhibits transcription regulator inhibitor activity (inferred); INVOLVED IN miRNA processing (inferred); mRNA processing (inferred); mRNA splicing, via spliceosome (inferred); ASSOCIATED WITH ARTERIAL DISSECTION (ortholog); benign epilepsy with centrotemporal spikes (ortholog) ; Psychomotor Retardation, Epilepsy, and Craniofacial Dysmorphism (ortholog); FOUND IN nucleoplasm (inferred); nucleus (inferred); spliceosomal complex (inferred) | | | | Pig | 35 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18694101 | SNIP1 | Smad nuclear interacting protein 1 | ENCODES a protein that exhibits transcription regulator inhibitor activity (inferred); INVOLVED IN miRNA processing (inferred); mRNA processing (inferred); mRNA splicing, via spliceosome (inferred); ASSOCIATED WITH ARTERIAL DISSECTION (ortholog); benign epilepsy with centrotemporal spikes (ortholog) ; Psychomotor Retardation, Epilepsy, and Craniofacial Dysmorphism (ortholog); FOUND IN nucleoplasm (inferred); nucleus (inferred); spliceosomal complex (inferred) | | | | Green Monkey | 32 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626124374 | Snip1 | Smad nuclear interacting protein 1 | ENCODES a protein that exhibits transcription regulator inhibitor activity (ortholog); INVOLVED IN miRNA processing (ortholog); mRNA splicing, via spliceosome (ortholog); negative regulation of canonical NF-kappaB signal transduction (ortholog); ASSOCIATED WITH ARTERIAL DISSECTION (ortholog); benign epilepsy with centrotemporal spikes (ortholog); Psychomotor Retardation, Epilepsy, and Craniofacial Dysmorphism (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); spliceosomal complex (ortholog) | | | | Black Rat | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155240468 | snip1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155243420 | snip1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 41276740 | Snip1-ps2 | Smad nuclear interacting protein 1, pseudogene 2 | | 15 | 20632382 | 20648717 | Rat | | symbol , PhenoGen | gene, protein-coding, MODEL [RefSeq] |
| 1317471 | Sync | syncoilin | Acts upstream of or within intermediate filament-based process. Located in several cellular components, including Z disc; neuromuscular junction; and sarcolemma. Is expressed in tibialis anterior. Orthologous to human SYNC (syncoilin, intermediate filament protein). [provided by Alliance of Genome R esources, Jul 2025] | 4 | 129181066 | 129203175 | Mouse | 87 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 2299009 | BCAR4 | breast cancer anti-estrogen resistance 4 | This gene produces a spliced long non-coding RNA (lncRNA) that has been implicated in breast cancer metastasis. It was originally identified in a screen for genes responsible for the development of resistance to anti-estrogens in breast cancer cells. It is thought that release of CCL21 enables this lncRNA to bind to the SNIP1 and PNUTS transcription factors, thereby activating a non-canonical GLI-dependent hedgehog signaling pathway that promotes cancer cell migration and invasion. A similar gene in cow expresses a protein in mature oocytes and preimplantation embryos. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Apr 2015] | 16 | 11819830 | 11828832 | Human | 4 | description | gene, ncrna, VALIDATED [RefSeq] |
