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19 records found for search term Sirt3
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
1308374Sirt3sirtuin 3ENCODES a protein that exhibits enzyme binding; histone H3K14 deacetylase activity, NAD-dependent (ortholog); NAD-dependent protein lysine deacetylase activity (ortholog); INVOLVED IN negative regulation of ERK1 and ERK2 cascade; negative regulation of reactive oxygen species metabolic process; posi1205371703205394145Rat334symbol , old_gene_name , PhenoGengene, protein-coding, PROVISIONAL [RefSeq]
1318106SIRT3sirtuin 3SIRT3 encodes a member of the sirtuin family of class III histone deacetylases, homologs to the yeast Sir2 protein. The encoded protein is found exclusively in mitochondria, where it can eliminate reactive oxygen species, inhibit apoptosis, and prevent the forma11215030236931Human340symbol , COSMIC , description , Human Proteome Map , old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1318107Sirt3sirtuin 3Enables NAD-dependent protein lysine deacetylase activity; protein lysine deacetylase activity; and sequence-specific DNA binding activity. Involved in peptidyl-lysine deacetylation; positive regulation of ceramide biosynthetic process; and positive regulation of mitochondrial transcription. Acts up7140443576140462222Mouse383symbol , old_gene_name , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
8763331Sirt3sirtuin 3ENCODES a protein that exhibits enzyme binding (ortholog); histone H3K14 deacetylase activity, NAD-dependent (ortholog); NAD-dependent protein lysine deacetylase activity (ortholog); INVOLVED IN aerobic respiration (ortholog); negative regulation of ERK1 and ERK2 cascade (ortholog); negative regulatNW_0049554761179495111826244Chinchilla64symbolgene, protein-coding, MODEL [RefSeq]
11981751SIRT3sirtuin 3ENCODES a protein that exhibits enzyme binding (ortholog); histone H3K14 deacetylase activity, NAD-dependent (ortholog); INVOLVED IN negative regulation of ERK1 and ERK2 cascade (ortholog); negative regulation of peptidyl-lysine acetylation (ortholog); negative regulation of reactive oxygen species 11210052233969Bonobo72symbolgene, protein-coding, MODEL [RefSeq]
12174970SIRT3sirtuin 3ENCODES a protein that exhibits enzyme binding (ortholog); histone H3K14 deacetylase activity, NAD-dependent (ortholog); INVOLVED IN negative regulation of ERK1 and ERK2 cascade (ortholog); negative regulation of peptidyl-lysine acetylation (ortholog); negative regulation of reactive oxygen species 182536918325388126Dog69symbolgene, protein-coding, MODEL [RefSeq]
12634292Sirt3sirtuin 3ENCODES a protein that exhibits enzyme binding (ortholog); histone H3K14 deacetylase activity, NAD-dependent (ortholog); INVOLVED IN negative regulation of ERK1 and ERK2 cascade (ortholog); negative regulation of peptidyl-lysine acetylation (ortholog); negative regulation of reactive oxygen species NW_0049368886313178536Squirrel71symbolgene, protein-coding, MODEL [RefSeq]
626156837Sirt3sirtuin 3ENCODES a protein that exhibits enzyme binding (ortholog); histone H3K14 deacetylase activity, NAD-dependent (ortholog); NAD-dependent protein lysine deacetylase activity (ortholog); INVOLVED IN aerobic respiration (ortholog); negative regulation of ERK1 and ERK2 cascade (ortholog); negative regulatBlack Rat64symbolgene, protein-coding, MODEL [RefSeq]
18440750SIRT3sirtuin 3ENCODES a protein that exhibits enzyme binding (ortholog); histone H3K14 deacetylase activity, NAD-dependent (ortholog); protein lysine deacetylase activity (ortholog); INVOLVED IN negative regulation of ERK1 and ERK2 cascade (ortholog); negative regulation of peptidyl-lysine acetylation (ortholog);Green Monkey67symbolgene, protein-coding, MODEL [RefSeq]
18917909Sirt3sirtuin 3ENCODES a protein that exhibits enzyme binding (ortholog); histone H3K14 deacetylase activity, NAD-dependent (ortholog); NAD-dependent protein lysine deacetylase activity (ortholog); INVOLVED IN aerobic respiration (ortholog); negative regulation of ERK1 and ERK2 cascade (ortholog); negative regulatNaked Mole-Rat74symbolgene, protein-coding, MODEL [RefSeq]
14276918SIRT3sirtuin 3ENCODES a protein that exhibits enzyme binding (ortholog); histone H3K14 deacetylase activity, NAD-dependent (ortholog); INVOLVED IN negative regulation of ERK1 and ERK2 cascade (ortholog); negative regulation of peptidyl-lysine acetylation (ortholog); negative regulation of reactive oxygen species Pig70symbolgene, protein-coding, PROVISIONAL [RefSeq]
284057528sirt3.1Tropical Clawed Frogsymbolgene, null
155259503sirt3.2Tropical Clawed Frogsymbolgene, null
286793136sirt3.1.SAfrican Clawed Frogsymbolgene, null
155259704sirt3.2.LAfrican Clawed Frogsymbolgene, null
10054451Sirt3em4Mcwisirtuin 3; CRISPR/Cas9 system induced mutant 4, Medical College of WisconsinThis allele was made by CRISPR/Cas9 system. The resulting mutation is a 7-bp deletion in the Sirt3 geneRatsymbol , description , old_gene_symbolgene, allele
10054448Sirt3em25Mcwisirtuin 3; CRISPR/Cas9 system induced mutant 25, Medical College of WisconsinThis allele was made by CRISPR/Cas9 system. The resulting mutation is a 13-bp deletion in the Sirt3 gene;(RGSC 5.0/rn5) deleted region: chr1:220,552,421-220,552,433Ratsymbol , description , old_gene_symbolgene, allele
10054457Sirt3em30Mcwisirtuin 3; CRISPR/Cas9 system induced mutant 30, Medical College of WisconsinThis allele was made by CRISPR/Cas9 system. The resulting mutation is a 31-bp deletion of exon 3 in the Sirt3 geneRatsymbol , description , old_gene_symbolgene, allele
10054454Sirt3em35Mcwisirtuin 3; CRISPR/Cas9 system induced mutant 35, Medical College of WisconsinThis allele was made by CRISPR/Cas9 system. The resulting mutation is a 82-bp deletion of exon 3 in the Sirt3 geneRatsymbol , description , old_gene_symbolgene, allele