SIRT3 Human (+)-schisandrin B multiple interactions ISO RGD:1308374 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of SIRT3 mRNA] CTD PMID:31150632 SIRT3 Human (-)-epigallocatechin 3-gallate decreases expression ISO RGD:1318107 6480464 epigallocatechin gallate results in decreased expression of SIRT3 mRNA; epigallocatechin gallate results in decreased expression more ... CTD PMID:29175576 SIRT3 Human (1->4)-beta-D-glucan multiple interactions ISO RGD:1318107 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of SIRT3 mRNA CTD PMID:36331819 SIRT3 Human (R)-carnitine multiple interactions ISO RGD:1318107 6480464 Carnitine inhibits the reaction [Cyclophosphamide results in increased expression of SIRT3 mRNA] CTD PMID:37863343 SIRT3 Human (R)-lipoic acid multiple interactions ISO RGD:1308374 6480464 [Thioctic Acid results in increased expression of [SIRT1 protein co-treated with SIRT3 protein]] which results more ... CTD PMID:22327056 SIRT3 Human (R)-lipoic acid multiple interactions ISO RGD:1318107 6480464 Thioctic Acid inhibits the reaction [Sodium Fluoride results in decreased expression of SIRT3 mRNA] CTD PMID:37739047 SIRT3 Human (R)-lipoic acid increases expression ISO RGD:1308374 6480464 Thioctic Acid results in increased expression of SIRT3 protein CTD PMID:22327056 SIRT3 Human 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane decreases expression ISO RGD:1318107 6480464 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane results in decreased expression of SIRT3 mRNA CTD PMID:25575267 SIRT3 Human 1,1-dichloroethene decreases expression ISO RGD:1318107 6480464 vinylidene chloride results in decreased expression of SIRT3 mRNA CTD PMID:26682919 SIRT3 Human 1,2-dimethylhydrazine decreases expression ISO RGD:1318107 6480464 1,2-Dimethylhydrazine results in decreased expression of SIRT3 mRNA CTD PMID:22206623 SIRT3 Human 1,2-dimethylhydrazine multiple interactions ISO RGD:1318107 6480464 [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of SIRT3 mRNA CTD PMID:22206623 SIRT3 Human 1,3,7,9-tetramethyluric acid multiple interactions ISO RGD:1308374 6480464 1,3,7,9-tetramethyluric acid inhibits the reaction [[Dietary Fats co-treated with Ethanol co-treated with Carbon Tetrachloride] results more ... CTD PMID:35872049 SIRT3 Human 17alpha-ethynylestradiol decreases expression ISO RGD:1308374 6480464 Ethinyl Estradiol results in decreased expression of SIRT3 mRNA CTD PMID:17557909 SIRT3 Human 17alpha-ethynylestradiol multiple interactions ISO RGD:1318107 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SIRT3 mRNA CTD PMID:17942748 SIRT3 Human 17beta-estradiol decreases expression ISO RGD:1318107 6480464 Estradiol results in decreased expression of SIRT3 mRNA CTD PMID:25575267|PMID:39298647 SIRT3 Human 17beta-estradiol decreases expression ISO RGD:1308374 6480464 Estradiol results in decreased expression of SIRT3 mRNA CTD PMID:32145629 SIRT3 Human 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1318107 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SIRT3 mRNA CTD PMID:17942748 SIRT3 Human 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1308374 6480464 Tetrachlorodibenzodioxin results in increased expression of SIRT3 mRNA CTD PMID:33387578 SIRT3 Human 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of SIRT3 mRNA CTD PMID:28011154 SIRT3 Human 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:1308374 6480464 Tetrachlorodibenzodioxin results in decreased expression of SIRT3 mRNA CTD PMID:21724226|PMID:32109520 SIRT3 Human 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1318107 6480464 Tetrachlorodibenzodioxin affects the expression of SIRT3 mRNA CTD PMID:21570461 SIRT3 Human 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:1318107 6480464 Tetrachlorodibenzodioxin results in decreased expression of SIRT3 mRNA CTD PMID:19770486 SIRT3 Human 2,4-dinitrotoluene affects expression ISO RGD:1308374 6480464 2,4-dinitrotoluene affects the expression of SIRT3 mRNA CTD PMID:21346803 SIRT3 Human 3,5-diethoxycarbonyl-1,4-dihydrocollidine decreases expression ISO RGD:1318107 6480464 Dicarbethoxydihydrocollidine results in decreased expression of SIRT3 mRNA CTD PMID:18098314 SIRT3 Human 3-chloropropane-1,2-diol increases expression ISO RGD:1318107 6480464 alpha-Chlorohydrin results in increased expression of SIRT3 mRNA CTD PMID:33913518 SIRT3 Human 4,4'-sulfonyldiphenol decreases expression ISO RGD:1318107 6480464 bisphenol S results in decreased expression of SIRT3 mRNA CTD PMID:39298647 SIRT3 Human 4-hydroxynon-2-enal multiple interactions EXP 6480464 4-hydroxy-2-nonenal binds to and results in decreased activity of SIRT3 protein CTD PMID:21449565 SIRT3 Human 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide decreases activity EXP 6480464 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide results in decreased activity of SIRT3 protein CTD PMID:26518726 SIRT3 Human 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide multiple interactions ISO RGD:1308374 6480464 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Dietary Fats results in decreased expression of SIRT3 protein] CTD PMID:31981641 SIRT3 Human 6-propyl-2-thiouracil decreases expression ISO RGD:1308374 6480464 Propylthiouracil results in decreased expression of SIRT3 mRNA CTD PMID:30047161 SIRT3 Human 8-Br-cAMP increases expression ISO RGD:1318107 6480464 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SIRT3 mRNA CTD PMID:23166782 SIRT3 Human ADP decreases abundance ISO RGD:1318107 6480464 SIRT3 protein results in decreased abundance of Adenosine Diphosphate CTD PMID:23166782 SIRT3 Human aldehydo-D-glucose multiple interactions ISO RGD:1318107 6480464 SIRT3 protein inhibits the reaction [sodium arsenite inhibits the reaction [INS1 protein results in increased more ... CTD PMID:25979314 SIRT3 Human aldehydo-D-glucose decreases expression EXP 6480464 Glucose results in decreased expression of SIRT3 protein CTD PMID:37417536 SIRT3 Human aldehydo-D-glucose multiple interactions ISO RGD:1308374 6480464 formononetin inhibits the reaction [Glucose results in decreased expression of SIRT3 mRNA]; formononetin inhibits the more ... CTD PMID:37944786 SIRT3 Human aldehydo-D-glucose decreases expression ISO RGD:1308374 6480464 Glucose results in decreased expression of SIRT3 mRNA; Glucose results in decreased expression of SIRT3 more ... CTD PMID:37944786 SIRT3 Human aldehydo-D-glucose increases expression EXP 6480464 Glucose deficiency results in increased expression of SIRT3 protein CTD PMID:23494737 SIRT3 Human aldehydo-D-glucose multiple interactions EXP 6480464 polyethylene glycol loxenatide inhibits the reaction [Glucose results in decreased expression of SIRT3 protein]; SIRT3 more ... CTD PMID:23494737|PMID:37417536 SIRT3 Human alpha-mangostin multiple interactions EXP 6480464 SIRT3 protein affects the reaction [mangostin results in decreased expression of ACTA2 protein]; SIRT3 protein more ... CTD PMID:30502394 SIRT3 Human alpha-mangostin multiple interactions ISO RGD:1318107 6480464 [mangostin co-treated with Carbon Tetrachloride] results in increased expression of and results in increased secretion more ... CTD PMID:30502394 SIRT3 Human alpha-mangostin increases expression EXP 6480464 mangostin results in increased expression of SIRT3 protein CTD PMID:30502394 SIRT3 Human amitrole decreases expression ISO RGD:1308374 6480464 Amitrole results in decreased expression of SIRT3 mRNA CTD PMID:30047161 SIRT3 Human antimycin A increases expression EXP 6480464 Antimycin A results in increased expression of SIRT3 mRNA CTD PMID:35430258 SIRT3 Human antimycin A multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Antimycin A results in increased expression of SIRT3 mRNA] CTD PMID:35430258 SIRT3 Human arsenous acid decreases expression ISO RGD:1308374 6480464 Arsenic Trioxide results in decreased expression of SIRT3 mRNA CTD PMID:29223816 SIRT3 Human arsenous acid increases expression ISO RGD:1308374 6480464 Arsenic Trioxide results in increased expression of SIRT3 protein CTD PMID:30385301 SIRT3 Human arsenous acid multiple interactions ISO RGD:1308374 6480464 [Arsenic Trioxide co-treated with Metformin] results in increased expression of SIRT3 protein CTD PMID:30385301 SIRT3 Human ATP multiple interactions ISO RGD:1318107 6480464 SIRT3 protein inhibits the reaction [Metformin results in decreased abundance of Adenosine Triphosphate] CTD PMID:23166782 SIRT3 Human atrazine affects expression EXP 6480464 Atrazine affects the expression of SIRT3 mRNA CTD PMID:27114639 SIRT3 Human atrazine decreases expression ISO RGD:1308374 6480464 Atrazine results in decreased expression of SIRT3 mRNA CTD PMID:27114639 SIRT3 Human benzo[a]pyrene decreases expression ISO RGD:1318107 6480464 Benzo(a)pyrene results in decreased expression of SIRT3 mRNA CTD PMID:19770486 SIRT3 Human benzo[a]pyrene multiple interactions ISO RGD:1308374 6480464 ramelteon inhibits the reaction [Benzo(a)pyrene results in increased expression of SIRT3 mRNA]; ramelteon inhibits the more ... CTD PMID:35940284 SIRT3 Human benzo[a]pyrene increases expression ISO RGD:1308374 6480464 Benzo(a)pyrene results in increased expression of SIRT3 mRNA; Benzo(a)pyrene results in increased expression of SIRT3 more ... CTD PMID:35940284 SIRT3 Human benzo[a]pyrene increases methylation EXP 6480464 Benzo(a)pyrene results in increased methylation of SIRT3 3' UTR CTD PMID:27901495 SIRT3 Human benzo[a]pyrene increases expression ISO RGD:1318107 6480464 Benzo(a)pyrene results in increased expression of SIRT3 mRNA CTD PMID:22228805 SIRT3 Human benzo[a]pyrene diol epoxide I increases expression EXP 6480464 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of SIRT3 mRNA; 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression more ... CTD PMID:35940284 SIRT3 Human berberine increases expression EXP 6480464 Berberine results in increased expression of SIRT3 mRNA CTD PMID:27311644 SIRT3 Human berberine multiple interactions EXP 6480464 [Berberine co-treated with Niacinamide] results in decreased expression of SIRT3 protein CTD PMID:26712469 SIRT3 Human berberine decreases expression EXP 6480464 Berberine results in decreased expression of SIRT3 mRNA; Berberine results in decreased expression of SIRT3 more ... CTD PMID:26712469 SIRT3 Human beta-lapachone increases expression EXP 6480464 beta-lapachone results in increased expression of SIRT3 mRNA CTD PMID:38218311 SIRT3 Human bis(2-ethylhexyl) phthalate multiple interactions ISO RGD:1318107 6480464 Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of SIRT3 protein] CTD PMID:33908429 SIRT3 Human bis(2-ethylhexyl) phthalate increases expression ISO RGD:1318107 6480464 Diethylhexyl Phthalate results in increased expression of SIRT3 mRNA; Diethylhexyl Phthalate results in increased expression more ... CTD PMID:33754040|PMID:33908429|PMID:34319233 SIRT3 Human bisphenol A decreases expression ISO RGD:1318107 6480464 bisphenol A results in decreased expression of SIRT3 mRNA CTD PMID:25575267|PMID:31016965|PMID:33239236 SIRT3 Human bisphenol A multiple interactions ISO RGD:1308374 6480464 Acetylcysteine inhibits the reaction [bisphenol A results in decreased expression of SIRT3 protein] CTD PMID:30641872 SIRT3 Human bisphenol A decreases expression ISO RGD:1308374 6480464 bisphenol A results in decreased expression of SIRT3 mRNA; bisphenol A results in decreased expression more ... CTD PMID:30641872|PMID:32145629|PMID:34947998 SIRT3 Human bisphenol A increases methylation ISO RGD:1308374 6480464 bisphenol A results in increased methylation of SIRT3 gene CTD PMID:28505145 SIRT3 Human bisphenol A increases methylation ISO RGD:1318107 6480464 bisphenol A results in increased methylation of SIRT3 promoter CTD PMID:27312807 SIRT3 Human bisphenol A increases expression ISO RGD:1308374 6480464 bisphenol A results in increased expression of SIRT3 mRNA CTD PMID:25181051 SIRT3 Human Butylbenzyl phthalate decreases expression EXP 6480464 butylbenzyl phthalate results in decreased expression of SIRT3 mRNA; butylbenzyl phthalate results in decreased expression more ... CTD PMID:26520405 SIRT3 Human Butylbenzyl phthalate decreases expression ISO RGD:1318107 6480464 butylbenzyl phthalate results in decreased expression of SIRT3 mRNA; butylbenzyl phthalate results in decreased expression more ... CTD PMID:27923775|PMID:34520170 SIRT3 Human cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of SIRT3 mRNA CTD PMID:38568856 SIRT3 Human caffeine multiple interactions EXP 6480464 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Caffeine inhibits the reaction [2,2'-azobis(2-amidinopropane) results in decreased expression of SIRT3 more ... CTD PMID:30555576 SIRT3 Human carbon nanotube decreases expression ISO RGD:1318107 6480464 Nanotubes, Carbon analog results in decreased expression of SIRT3 mRNA CTD PMID:25554681 SIRT3 Human CGS-21680 multiple interactions EXP 6480464 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Caffeine inhibits the reaction [2,2'-azobis(2-amidinopropane) results in decreased expression of SIRT3 more ... CTD PMID:30555576 SIRT3 Human chloroquine increases stability EXP 6480464 Chloroquine results in increased stability of SIRT3 mRNA CTD PMID:35302183 SIRT3 Human chloroquine multiple interactions EXP 6480464 Chloroquine inhibits the reaction [hydroquinone results in decreased expression of SIRT3 mRNA]; Chloroquine inhibits the more ... CTD PMID:35302183 SIRT3 Human choline multiple interactions ISO RGD:1318107 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation more ... CTD PMID:20938992 SIRT3 Human chromium(6+) affects response to substance EXP 6480464 SIRT3 affects the susceptibility to chromium hexavalent ion CTD PMID:30715550 SIRT3 Human chromium(6+) multiple interactions EXP 6480464 chromium hexavalent ion promotes the reaction [NFE2L2 protein binds to SIRT3 promoter] CTD PMID:30715550 SIRT3 Human chromium(6+) increases expression EXP 6480464 chromium hexavalent ion results in increased expression of SIRT3 mRNA; chromium hexavalent ion results in more ... CTD PMID:30715550 SIRT3 Human cisplatin multiple interactions ISO RGD:1318107 6480464 SIRT3 promotes the reaction [Metformin inhibits the reaction [Cisplatin affects the localization of SLC2A4 protein]]; more ... CTD PMID:36800006 SIRT3 Human cisplatin decreases expression ISO RGD:1308374 6480464 Cisplatin results in decreased expression of SIRT3 mRNA; Cisplatin results in decreased expression of SIRT3 more ... CTD PMID:36800006|PMID:39102946 SIRT3 Human cisplatin affects response to substance EXP 6480464 SIRT3 protein affects the susceptibility to Cisplatin CTD PMID:27722009 SIRT3 Human cisplatin multiple interactions EXP 6480464 Cisplatin results in decreased expression of and results in decreased activity of SIRT3 protein; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide more ... CTD PMID:27722009 SIRT3 Human cisplatin multiple interactions ISO RGD:1308374 6480464 Cisplatin results in decreased expression of and results in decreased activity of SIRT3 protein; Curcumin more ... CTD PMID:28698153|PMID:36800006|PMID:39102946 SIRT3 Human cisplatin decreases response to substance EXP 6480464 SIRT3 protein results in decreased susceptibility to Cisplatin CTD PMID:21472714 SIRT3 Human copper(II) sulfate decreases expression EXP 6480464 Copper Sulfate results in decreased expression of SIRT3 mRNA CTD PMID:19549813 SIRT3 Human curcumin multiple interactions ISO RGD:1308374 6480464 Curcumin inhibits the reaction [[Lipopolysaccharides co-treated with Tobacco Smoke Pollution] results in decreased expression of more ... CTD PMID:28698153|PMID:28951138 SIRT3 Human curcumin multiple interactions EXP 6480464 Curcumin inhibits the reaction [[GYY 4137 results in increased abundance of Hydrogen Sulfide] inhibits the more ... CTD PMID:26422756 SIRT3 Human cyclophosphamide multiple interactions ISO RGD:1318107 6480464 Carnitine inhibits the reaction [Cyclophosphamide results in increased expression of SIRT3 mRNA] CTD PMID:37863343 SIRT3 Human cyclophosphamide increases expression ISO RGD:1318107 6480464 Cyclophosphamide results in increased expression of SIRT3 mRNA CTD PMID:37863343 SIRT3 Human D-glucose multiple interactions ISO RGD:1318107 6480464 SIRT3 protein inhibits the reaction [sodium arsenite inhibits the reaction [INS1 protein results in increased more ... CTD PMID:25979314 SIRT3 Human D-glucose decreases expression EXP 6480464 Glucose results in decreased expression of SIRT3 protein CTD PMID:37417536 SIRT3 Human D-glucose multiple interactions ISO RGD:1308374 6480464 formononetin inhibits the reaction [Glucose results in decreased expression of SIRT3 mRNA]; formononetin inhibits the more ... CTD PMID:37944786 SIRT3 Human D-glucose decreases expression ISO RGD:1308374 6480464 Glucose results in decreased expression of SIRT3 mRNA; Glucose results in decreased expression of SIRT3 more ... CTD PMID:37944786 SIRT3 Human D-glucose multiple interactions EXP 6480464 polyethylene glycol loxenatide inhibits the reaction [Glucose results in decreased expression of SIRT3 protein]; SIRT3 more ... CTD PMID:23494737|PMID:37417536 SIRT3 Human D-glucose increases expression EXP 6480464 Glucose deficiency results in increased expression of SIRT3 protein CTD PMID:23494737 SIRT3 Human deguelin decreases expression EXP 6480464 deguelin results in decreased expression of SIRT3 mRNA CTD PMID:33512557 SIRT3 Human diarsenic trioxide multiple interactions ISO RGD:1308374 6480464 [Arsenic Trioxide co-treated with Metformin] results in increased expression of SIRT3 protein CTD PMID:30385301 SIRT3 Human diarsenic trioxide increases expression ISO RGD:1308374 6480464 Arsenic Trioxide results in increased expression of SIRT3 protein CTD PMID:30385301 SIRT3 Human diarsenic trioxide decreases expression ISO RGD:1308374 6480464 Arsenic Trioxide results in decreased expression of SIRT3 mRNA CTD PMID:29223816 SIRT3 Human diazinon increases methylation EXP 6480464 Diazinon results in increased methylation of SIRT3 gene CTD PMID:22964155 SIRT3 Human Dibutyl phosphate affects expression EXP 6480464 di-n-butylphosphoric acid affects the expression of SIRT3 mRNA CTD PMID:37042841 SIRT3 Human dibutyl phthalate decreases expression ISO RGD:1308374 6480464 Dibutyl Phthalate results in decreased expression of SIRT3 mRNA CTD PMID:21266533 SIRT3 Human diethylstilbestrol decreases expression ISO RGD:1318107 6480464 Diethylstilbestrol results in decreased expression of SIRT3 mRNA CTD PMID:25575267 SIRT3 Human diisononyl phthalate decreases expression EXP 6480464 diisononyl phthalate results in decreased expression of SIRT3 mRNA; diisononyl phthalate results in decreased expression more ... CTD PMID:31423773 SIRT3 Human Diosbulbin B decreases expression ISO RGD:1318107 6480464 diosbulbin B results in decreased expression of SIRT3 mRNA CTD PMID:39368342 SIRT3 Human doxorubicin decreases expression ISO RGD:1308374 6480464 Doxorubicin results in decreased expression of SIRT3 protein CTD PMID:26678157 SIRT3 Human doxorubicin decreases expression EXP 6480464 Doxorubicin results in decreased expression of SIRT3 mRNA CTD PMID:29803840 SIRT3 Human estriol decreases expression ISO RGD:1318107 6480464 Estriol results in decreased expression of SIRT3 mRNA CTD PMID:25575267 SIRT3 Human ethanol increases metabolic processing ISO RGD:1318107 6480464 Ethanol results in increased metabolism of SIRT3 protein CTD PMID:21449565 SIRT3 Human ethanol increases expression ISO RGD:1308374 6480464 Ethanol results in increased expression of SIRT3 mRNA CTD PMID:18793633 SIRT3 Human ethanol multiple interactions ISO RGD:1308374 6480464 1,3,7,9-tetramethyluric acid inhibits the reaction [[Dietary Fats co-treated with Ethanol co-treated with Carbon Tetrachloride] results more ... CTD PMID:18793633|PMID:35872049 SIRT3 Human flutamide decreases expression ISO RGD:1308374 6480464 Flutamide results in decreased expression of SIRT3 mRNA CTD PMID:24136188 SIRT3 Human folic acid multiple interactions ISO RGD:1318107 6480464 [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of SIRT3 mRNA; [Methionine deficiency co-treated more ... CTD PMID:20938992|PMID:22206623 SIRT3 Human formononetin affects binding ISO RGD:1308374 6480464 formononetin binds to SIRT3 protein CTD PMID:37944786 SIRT3 Human formononetin multiple interactions ISO RGD:1308374 6480464 formononetin inhibits the reaction [Glucose results in decreased expression of SIRT3 mRNA]; formononetin inhibits the more ... CTD PMID:37944786 SIRT3 Human gemcitabine multiple interactions ISO RGD:1318107 6480464 [3-(carbamoylamino)-5-(3-fluorophenyl)-N-(3-piperidyl)thiophene-2-carboxamide co-treated with Gemcitabine] results in decreased expression of SIRT3 protein CTD PMID:37798514 SIRT3 Human gemcitabine decreases expression ISO RGD:1318107 6480464 Gemcitabine results in decreased expression of SIRT3 protein CTD PMID:37798514 SIRT3 Human gentamycin increases expression ISO RGD:1308374 6480464 Gentamicins results in increased expression of SIRT3 mRNA CTD PMID:33387578 SIRT3 Human glucose multiple interactions ISO RGD:1318107 6480464 SIRT3 protein inhibits the reaction [sodium arsenite inhibits the reaction [INS1 protein results in increased more ... CTD PMID:25979314 SIRT3 Human glucose decreases expression EXP 6480464 Glucose results in decreased expression of SIRT3 protein CTD PMID:37417536 SIRT3 Human glucose decreases expression ISO RGD:1308374 6480464 Glucose results in decreased expression of SIRT3 mRNA; Glucose results in decreased expression of SIRT3 more ... CTD PMID:37944786 SIRT3 Human glucose multiple interactions ISO RGD:1308374 6480464 formononetin inhibits the reaction [Glucose results in decreased expression of SIRT3 mRNA]; formononetin inhibits the more ... CTD PMID:37944786 SIRT3 Human glucose increases expression EXP 6480464 Glucose deficiency results in increased expression of SIRT3 protein CTD PMID:23494737 SIRT3 Human glucose multiple interactions EXP 6480464 polyethylene glycol loxenatide inhibits the reaction [Glucose results in decreased expression of SIRT3 protein]; SIRT3 more ... CTD PMID:23494737|PMID:37417536 SIRT3 Human GSK-J4 decreases expression EXP 6480464 GSK-J4 results in decreased expression of SIRT3 mRNA CTD PMID:29301935 SIRT3 Human hesperetin affects binding EXP 6480464 hesperetin binds to SIRT3 protein CTD PMID:37487865 SIRT3 Human hexadecanoic acid decreases expression EXP 6480464 Palmitic Acid results in decreased expression of SIRT3 protein CTD PMID:30958623 SIRT3 Human Honokiol multiple interactions ISO RGD:1308374 6480464 honokiol inhibits the reaction [amyloid beta-protein (1-42) results in decreased expression of SIRT3 protein]; honokiol more ... CTD PMID:33522075|PMID:34752757 SIRT3 Human hydrogen peroxide multiple interactions ISO RGD:1308374 6480464 Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of SIRT3 mRNA]; Acetylcysteine inhibits more ... CTD PMID:30104959 SIRT3 Human hydrogen peroxide decreases expression EXP 6480464 Hydrogen Peroxide results in decreased expression of SIRT3 mRNA; Hydrogen Peroxide results in decreased expression more ... CTD PMID:26422756 SIRT3 Human hydrogen peroxide multiple interactions EXP 6480464 [GYY 4137 results in increased abundance of Hydrogen Sulfide] inhibits the reaction [Hydrogen Peroxide results more ... CTD PMID:26422756 SIRT3 Human hydrogen peroxide decreases expression ISO RGD:1308374 6480464 Hydrogen Peroxide results in decreased expression of SIRT3 mRNA; Hydrogen Peroxide results in decreased expression more ... CTD PMID:30104959 SIRT3 Human hydrogen sulfide multiple interactions ISO RGD:1308374 6480464 [sodium sulfide results in increased abundance of Hydrogen Sulfide] inhibits the reaction [Paraquat results in more ... CTD PMID:32064027 SIRT3 Human hydrogen sulfide multiple interactions EXP 6480464 [GYY 4137 results in increased abundance of Hydrogen Sulfide] inhibits the reaction [Hydrogen Peroxide results more ... CTD PMID:26422756 SIRT3 Human hydroquinone decreases expression EXP 6480464 hydroquinone results in decreased expression of SIRT3 mRNA; hydroquinone results in decreased expression of SIRT3 more ... CTD PMID:35302183 SIRT3 Human hydroquinone increases degradation EXP 6480464 hydroquinone results in increased degradation of SIRT3 mRNA CTD PMID:35302183 SIRT3 Human hydroquinone multiple interactions EXP 6480464 [[NOX4 protein results in decreased expression of ELAVL2 protein] which promotes the reaction SIDT2 protein] more ... CTD PMID:35302183 SIRT3 Human icariin multiple interactions ISO RGD:1308374 6480464 Histone Deacetylase Inhibitors inhibits the reaction [icariin inhibits the reaction [Rotenone results in decreased expression more ... CTD PMID:31251943 SIRT3 Human L-methionine multiple interactions ISO RGD:1318107 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation more ... CTD PMID:20938992 SIRT3 Human lead diacetate multiple interactions ISO RGD:1318107 6480464 PPARGC1A protein affects the reaction [lead acetate results in increased expression of SIRT3 protein] CTD PMID:27236077 SIRT3 Human lead diacetate increases expression ISO RGD:1318107 6480464 lead acetate results in increased expression of SIRT3 protein CTD PMID:27236077 SIRT3 Human linagliptin multiple interactions ISO RGD:1308374 6480464 Linagliptin inhibits the reaction [Cisplatin results in decreased expression of SIRT3 mRNA] CTD PMID:39102946 SIRT3 Human linalool multiple interactions EXP 6480464 linalool inhibits the reaction [SOD2 protein binds to SIRT3 protein] CTD PMID:28567457 SIRT3 Human linalool decreases expression EXP 6480464 linalool results in decreased expression of SIRT3 mRNA; linalool results in decreased expression of SIRT3 more ... CTD PMID:28567457 SIRT3 Human lipoic acid multiple interactions ISO RGD:1308374 6480464 [Thioctic Acid results in increased expression of [SIRT1 protein co-treated with SIRT3 protein]] which results more ... CTD PMID:22327056 SIRT3 Human lipoic acid multiple interactions ISO RGD:1318107 6480464 Thioctic Acid inhibits the reaction [Sodium Fluoride results in decreased expression of SIRT3 mRNA] CTD PMID:37739047 SIRT3 Human lipoic acid increases expression ISO RGD:1308374 6480464 Thioctic Acid results in increased expression of SIRT3 protein CTD PMID:22327056 SIRT3 Human lipopolysaccharide multiple interactions ISO RGD:1308374 6480464 [Lipopolysaccharides co-treated with Tobacco Smoke Pollution] results in decreased expression of SIRT3 mRNA; [Lipopolysaccharides co-treated more ... CTD PMID:28951138 SIRT3 Human lycopene multiple interactions ISO RGD:1318107 6480464 Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of SIRT3 protein] CTD PMID:33908429 SIRT3 Human mancozeb decreases activity EXP 6480464 mancozeb results in decreased activity of SIRT3 protein CTD PMID:21251949 SIRT3 Human maneb decreases activity EXP 6480464 Maneb results in decreased activity of SIRT3 protein CTD PMID:21251949 SIRT3 Human melatonin multiple interactions ISO RGD:1308374 6480464 Melatonin inhibits the reaction [Monocrotaline results in decreased expression of SIRT3 mRNA]; Melatonin inhibits the more ... CTD PMID:37350538 SIRT3 Human melatonin multiple interactions ISO RGD:1318107 6480464 Melatonin inhibits the reaction [[Particulate Matter co-treated with Dietary Fats] results in decreased expression of more ... CTD PMID:37994397 SIRT3 Human metformin decreases expression ISO RGD:1318107 6480464 Metformin results in decreased expression of SIRT3 mRNA; Metformin results in decreased expression of SIRT3 more ... CTD PMID:23166782|PMID:24687991 SIRT3 Human metformin multiple interactions EXP 6480464 Metformin results in increased expression of and results in increased activity of SIRT3 protein CTD PMID:33147367 SIRT3 Human metformin multiple interactions ISO RGD:1308374 6480464 [Arsenic Trioxide co-treated with Metformin] results in increased expression of SIRT3 protein; Metformin inhibits the more ... CTD PMID:30385301|PMID:36800006 SIRT3 Human metformin increases expression ISO RGD:1308374 6480464 Metformin results in increased expression of SIRT3 protein CTD PMID:30385301 SIRT3 Human metformin multiple interactions ISO RGD:1318107 6480464 Metformin inhibits the reaction [GCG protein results in increased expression of SIRT3 mRNA]; SIRT3 promotes more ... CTD PMID:23166782|PMID:36800006 SIRT3 Human metformin decreases response to substance ISO RGD:1318107 6480464 SIRT3 protein results in decreased susceptibility to Metformin CTD PMID:23166782 SIRT3 Human methimazole decreases expression ISO RGD:1308374 6480464 Methimazole results in decreased expression of SIRT3 mRNA CTD PMID:30047161 SIRT3 Human methotrexate affects expression ISO RGD:1318107 6480464 Methotrexate affects the expression of SIRT3 mRNA CTD PMID:18502557 SIRT3 Human metiram decreases activity EXP 6480464 polymarcine results in decreased activity of SIRT3 protein CTD PMID:21251949 SIRT3 Human mono(2-ethylhexyl) phthalate increases expression ISO RGD:1318107 6480464 mono-(2-ethylhexyl)phthalate results in increased expression of SIRT3 mRNA CTD PMID:25543134|PMID:32522588 SIRT3 Human mono(2-ethylhexyl) phthalate decreases expression ISO RGD:1318107 6480464 mono-(2-ethylhexyl)phthalate results in decreased expression of SIRT3 mRNA; mono-(2-ethylhexyl)phthalate results in decreased expression of SIRT3 more ... CTD PMID:31016965 SIRT3 Human monocrotaline decreases expression ISO RGD:1308374 6480464 Monocrotaline results in decreased expression of SIRT3 mRNA; Monocrotaline results in decreased expression of SIRT3 more ... CTD PMID:37350538 SIRT3 Human monocrotaline multiple interactions ISO RGD:1308374 6480464 Melatonin inhibits the reaction [Monocrotaline results in decreased expression of SIRT3 mRNA]; Melatonin inhibits the more ... CTD PMID:37350538 SIRT3 Human N-acetyl-L-cysteine multiple interactions ISO RGD:1308374 6480464 Acetylcysteine inhibits the reaction [bisphenol A results in decreased expression of SIRT3 protein]; Acetylcysteine inhibits more ... CTD PMID:30104959|PMID:30641872 SIRT3 Human N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Antimycin A results in increased expression of SIRT3 mRNA] CTD PMID:35430258 SIRT3 Human N-methyl-4-phenylpyridinium increases expression ISO RGD:1308374 6480464 1-Methyl-4-phenylpyridinium results in increased expression of SIRT3 mRNA CTD PMID:28801915 SIRT3 Human N-methyl-4-phenylpyridinium decreases expression ISO RGD:1318107 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of SIRT3 protein CTD PMID:33994527 SIRT3 Human N-methyl-4-phenylpyridinium multiple interactions ISO RGD:1318107 6480464 salvianolic acid B inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of SIRT3 protein] CTD PMID:33994527 SIRT3 Human nebivolol multiple interactions ISO RGD:1318107 6480464 3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate inhibits the reaction [Nebivolol results in increased expression of SIRT3 protein] CTD PMID:23886954 SIRT3 Human nebivolol increases expression ISO RGD:1318107 6480464 Nebivolol results in increased expression of SIRT3 protein CTD PMID:23886954 SIRT3 Human nicotinamide multiple interactions EXP 6480464 [Berberine co-treated with Niacinamide] results in decreased expression of SIRT3 protein CTD PMID:26712469 SIRT3 Human nitrates multiple interactions ISO RGD:1318107 6480464 [Particulate Matter results in increased abundance of Nitrates] which results in increased expression of SIRT3 more ... CTD PMID:35964746 SIRT3 Human okadaic acid decreases expression EXP 6480464 Okadaic Acid results in decreased expression of SIRT3 mRNA CTD PMID:38832940 SIRT3 Human paracetamol affects expression ISO RGD:1318107 6480464 Acetaminophen affects the expression of SIRT3 mRNA CTD PMID:17562736 SIRT3 Human paracetamol increases expression ISO RGD:1308374 6480464 Acetaminophen results in increased expression of SIRT3 mRNA CTD PMID:33387578 SIRT3 Human paraquat decreases expression ISO RGD:1308374 6480464 Paraquat results in decreased expression of SIRT3 protein CTD PMID:32064027 SIRT3 Human paraquat multiple interactions ISO RGD:1308374 6480464 [sodium sulfide results in increased abundance of Hydrogen Sulfide] inhibits the reaction [Paraquat results in more ... CTD PMID:32064027 SIRT3 Human perfluorooctane-1-sulfonic acid increases expression ISO RGD:1318107 6480464 perfluorooctane sulfonic acid results in increased expression of SIRT3 mRNA CTD PMID:31016965 SIRT3 Human perfluorooctane-1-sulfonic acid multiple interactions ISO RGD:1318107 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of SIRT3 mRNA CTD PMID:36331819 SIRT3 Human perfluorooctane-1-sulfonic acid decreases expression EXP 6480464 perfluorooctane sulfonic acid results in decreased expression of SIRT3 mRNA; perfluorooctane sulfonic acid results in more ... CTD PMID:31508952 SIRT3 Human perfluorooctanoic acid increases expression ISO RGD:1318107 6480464 perfluorooctanoic acid results in increased expression of SIRT3 mRNA CTD PMID:31016965 SIRT3 Human pregnenolone 16alpha-carbonitrile decreases expression ISO RGD:1308374 6480464 Pregnenolone Carbonitrile results in decreased expression of SIRT3 mRNA CTD PMID:30047161 SIRT3 Human propiconazole decreases expression ISO RGD:1318107 6480464 propiconazole results in decreased expression of SIRT3 mRNA CTD PMID:21278054 SIRT3 Human propionic acid increases expression EXP 6480464 propionic acid results in increased expression of SIRT3 mRNA; propionic acid results in increased expression more ... CTD PMID:31526819 SIRT3 Human reactive oxygen species multiple interactions EXP 6480464 SIRT3 protein inhibits the reaction [Particulate Matter results in increased abundance of Reactive Oxygen Species] CTD PMID:27125970 SIRT3 Human resveratrol decreases expression EXP 6480464 resveratrol results in decreased expression of SIRT3 mRNA CTD PMID:21980390 SIRT3 Human resveratrol decreases expression ISO RGD:1318107 6480464 resveratrol results in decreased expression of SIRT3 mRNA CTD PMID:23525482 SIRT3 Human resveratrol increases activity EXP 6480464 resveratrol results in increased activity of SIRT3 protein CTD PMID:24178296 SIRT3 Human resveratrol multiple interactions ISO RGD:1308374 6480464 resveratrol inhibits the reaction [Dietary Fats results in decreased expression of SIRT3 protein]; resveratrol inhibits more ... CTD PMID:18793633|PMID:25686565 SIRT3 Human resveratrol increases expression EXP 6480464 resveratrol results in increased expression of SIRT3 mRNA CTD PMID:25522270 SIRT3 Human resveratrol multiple interactions EXP 6480464 PPARGC1A mutant form inhibits the reaction [resveratrol results in increased expression of SIRT3 mRNA]; PPARGC1A more ... CTD PMID:22585829|PMID:25522270 SIRT3 Human rotenone multiple interactions EXP 6480464 SIRT3 protein inhibits the reaction [Rotenone results in increased expression of SNCA protein] CTD PMID:27053302 SIRT3 Human rotenone decreases expression ISO RGD:1308374 6480464 Rotenone results in decreased expression of SIRT3 protein CTD PMID:31251943 SIRT3 Human rotenone multiple interactions ISO RGD:1308374 6480464 Histone Deacetylase Inhibitors inhibits the reaction [icariin inhibits the reaction [Rotenone results in decreased expression more ... CTD PMID:31251943 SIRT3 Human salvianolic acid B multiple interactions ISO RGD:1318107 6480464 salvianolic acid B inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of SIRT3 protein] CTD PMID:33994527 SIRT3 Human sodium arsenite multiple interactions ISO RGD:1318107 6480464 SIRT3 protein inhibits the reaction [sodium arsenite inhibits the reaction [FOXO3 protein binds to PPARGC1A more ... CTD PMID:25979314 SIRT3 Human sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of SIRT3 mRNA CTD PMID:38568856 SIRT3 Human sodium arsenite decreases expression ISO RGD:1318107 6480464 sodium arsenite results in decreased expression of SIRT3 protein CTD PMID:25979314 SIRT3 Human sodium fluoride multiple interactions ISO RGD:1318107 6480464 [Sodium Fluoride results in increased abundance of Fluorides] which results in decreased expression of SIRT3 more ... CTD PMID:34780879|PMID:37739047 SIRT3 Human sodium fluoride decreases expression ISO RGD:1318107 6480464 Sodium Fluoride results in decreased expression of SIRT3 mRNA CTD PMID:37739047 SIRT3 Human sodium fluoride multiple interactions ISO RGD:1308374 6480464 [Sodium Fluoride results in increased abundance of Fluorides] which results in increased expression of SIRT3 more ... CTD PMID:39012504 SIRT3 Human sodium fluoride multiple interactions EXP 6480464 [Sodium Fluoride results in increased abundance of Fluorides] which results in decreased expression of SIRT3 more ... CTD PMID:34780879|PMID:39012504 SIRT3 Human sodium sulfide (anhydrous) multiple interactions ISO RGD:1308374 6480464 [sodium sulfide results in increased abundance of Hydrogen Sulfide] inhibits the reaction [Paraquat results in more ... CTD PMID:32064027 SIRT3 Human Soman decreases expression ISO RGD:1308374 6480464 Soman results in decreased expression of SIRT3 mRNA CTD PMID:19281266 SIRT3 Human stavudine increases expression EXP 6480464 Stavudine results in increased expression of SIRT3 protein CTD PMID:27041070 SIRT3 Human sulfadimethoxine decreases expression ISO RGD:1308374 6480464 Sulfadimethoxine results in decreased expression of SIRT3 mRNA CTD PMID:30047161 SIRT3 Human tenofovir disoproxil fumarate increases expression EXP 6480464 Tenofovir results in increased expression of SIRT3 protein CTD PMID:27041070 SIRT3 Human tert-butyl hydroperoxide multiple interactions EXP 6480464 SIRT3 mutant form inhibits the reaction [resveratrol inhibits the reaction [tert-Butylhydroperoxide results in decreased activity more ... CTD PMID:25522270 SIRT3 Human tetrachloromethane decreases expression ISO RGD:1318107 6480464 Carbon Tetrachloride results in decreased expression of SIRT3 mRNA; Carbon Tetrachloride results in decreased expression more ... CTD PMID:27339419|PMID:30368983|PMID:31919559 SIRT3 Human tetrachloromethane decreases response to substance ISO RGD:1318107 6480464 SIRT3 protein results in decreased susceptibility to Carbon Tetrachloride CTD PMID:30368983 SIRT3 Human tetrachloromethane decreases expression ISO RGD:1308374 6480464 Carbon Tetrachloride results in decreased expression of SIRT3 mRNA CTD PMID:31150632 SIRT3 Human tetrachloromethane multiple interactions ISO RGD:1318107 6480464 [mangostin co-treated with Carbon Tetrachloride] results in increased expression of and results in increased secretion more ... CTD PMID:30368983|PMID:30502394 SIRT3 Human tetrachloromethane multiple interactions ISO RGD:1308374 6480464 1,3,7,9-tetramethyluric acid inhibits the reaction [[Dietary Fats co-treated with Ethanol co-treated with Carbon Tetrachloride] results more ... CTD PMID:31150632|PMID:35872049 SIRT3 Human thapsigargin decreases expression EXP 6480464 Thapsigargin results in decreased expression of SIRT3 mRNA CTD PMID:22378314 SIRT3 Human thioacetamide multiple interactions ISO RGD:1308374 6480464 honokiol inhibits the reaction [Thioacetamide results in decreased expression of and results in decreased activity more ... CTD PMID:33522075 SIRT3 Human thioacetamide decreases expression ISO RGD:1308374 6480464 Thioacetamide results in decreased expression of SIRT3 mRNA CTD PMID:34492290 SIRT3 Human thiram decreases expression EXP 6480464 Thiram results in decreased expression of SIRT3 mRNA CTD PMID:38568856 SIRT3 Human titanium dioxide decreases methylation ISO RGD:1318107 6480464 titanium dioxide results in decreased methylation of SIRT3 gene; titanium dioxide results in decreased methylation more ... CTD PMID:35295148 SIRT3 Human trichloroethene increases expression ISO RGD:1308374 6480464 Trichloroethylene results in increased expression of SIRT3 mRNA CTD PMID:33387578 SIRT3 Human trilobatin multiple interactions ISO RGD:1308374 6480464 trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of SIRT3 mRNA]; trilobatin inhibits more ... CTD PMID:30104959 SIRT3 Human triptonide increases expression ISO RGD:1318107 6480464 triptonide results in increased expression of SIRT3 mRNA CTD PMID:33045310 SIRT3 Human tris(2-chloroethyl) phosphate decreases expression EXP 6480464 tris(chloroethyl)phosphate results in decreased expression of SIRT3 mRNA; tris(chloroethyl)phosphate results in decreased expression of SIRT3 more ... CTD PMID:30090360 SIRT3 Human tunicamycin decreases expression EXP 6480464 Tunicamycin results in decreased expression of SIRT3 mRNA CTD PMID:22378314 SIRT3 Human urethane decreases expression EXP 6480464 Urethane results in decreased expression of SIRT3 mRNA CTD PMID:28818685 SIRT3 Human valdecoxib decreases expression ISO RGD:1308374 6480464 valdecoxib results in decreased expression of SIRT3 mRNA CTD PMID:24136188 SIRT3 Human valproic acid decreases methylation EXP 6480464 Valproic Acid results in decreased methylation of SIRT3 gene CTD PMID:29154799 SIRT3 Human vancomycin increases expression ISO RGD:1318107 6480464 Vancomycin results in increased expression of SIRT3 mRNA CTD PMID:18930951 SIRT3 Human vosaroxin multiple interactions EXP 6480464 SIRT3 protein inhibits the reaction [vosaroxin results in decreased expression of HIF1A protein] CTD PMID:29800573 SIRT3 Human zidovudine increases expression EXP 6480464 Zidovudine results in increased expression of SIRT3 protein CTD PMID:27041070
