| 1308482 | Sfxn1 | sideroflexin 1 | ENCODES a protein that exhibits L-alanine transmembrane transporter activity (ortholog); L-serine transmembrane transporter activity (ortholog); INVOLVED IN erythrocyte differentiation (ortholog); iron ion transport (ortholog); L-alanine transport (ortholog); ASSOCIATED WITH Animal Disease Models (o rtholog); Colorectal Neoplasms (ortholog); lung adenocarcinoma (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,2,2-tetramine; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 17 | 10491315 | 10527793 | Rat | 184 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1318276 | SFXN1 | sideroflexin 1 | Enables L-alanine transmembrane transporter activity and L-serine transmembrane transporter activity. Involved in L-alanine transport; L-serine transport; and serine import into mitochondrion. Located in mitochondrial inner membrane. [provided by Alliance of Genome Resources, Jul 2025] | 5 | 175478560 | 175529742 | Human | 169 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1318277 | Sfxn1 | sideroflexin 1 | Enables L-serine transmembrane transporter activity. Involved in serine import into mitochondrion. Acts upstream of or within erythrocyte differentiation and iron ion transport. Located in mitochondrion. Is expressed in several structures, including alimentary system; brain; genitourinary system; im mune system; and integumental system. Orthologous to human SFXN1 (sideroflexin 1). [provided by Alliance of Genome Resources, Jul 2025] | 13 | 54225675 | 54262365 | Mouse | 188 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 9016007 | Sfxn1 | sideroflexin 1 | ENCODES a protein that exhibits L-alanine transmembrane transporter activity (ortholog); L-serine transmembrane transporter activity (ortholog); INVOLVED IN erythrocyte differentiation (ortholog); iron ion transport (ortholog); L-alanine transport (ortholog); ASSOCIATED WITH Animal Disease Models (o rtholog); Colorectal Neoplasms (ortholog); lung adenocarcinoma (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog) | NW_004955408 | 28054211 | 28105294 | Chinchilla | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11692163 | SFXN1 | sideroflexin 1 | ENCODES a protein that exhibits L-alanine transmembrane transporter activity (inferred); L-serine transmembrane transporter activity (inferred); monoatomic ion transmembrane transporter activity (inferred); INVOLVED IN erythrocyte differentiation (ortholog); iron ion transport (ortholog); one-carbon metabolic process (ortholog); ASSOCIATED WITH Animal Disease Models (ortholog); Colorectal Neoplasms (ortholog); lung adenocarcinoma (ortholog); FOUND IN membrane (inferred); mitochondrial inner membrane (inferred); mitochondrial membrane (inferred) | 5 | 170825507 | 170876741 | Bonobo | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12185875 | SFXN1 | sideroflexin 1 | ENCODES a protein that exhibits L-alanine transmembrane transporter activity (inferred); L-serine transmembrane transporter activity (inferred); monoatomic ion transmembrane transporter activity (inferred); INVOLVED IN erythrocyte differentiation (ortholog); iron ion transport (ortholog); one-carbon metabolic process (ortholog); ASSOCIATED WITH Animal Disease Models (ortholog); Colorectal Neoplasms (ortholog); lung adenocarcinoma (ortholog); FOUND IN membrane (inferred); mitochondrial inner membrane (inferred); mitochondrial membrane (inferred) | 4 | 37485360 | 37517743 | Dog | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12562987 | Sfxn1 | sideroflexin 1 | ENCODES a protein that exhibits L-alanine transmembrane transporter activity (inferred); L-serine transmembrane transporter activity (inferred); monoatomic ion transmembrane transporter activity (inferred); INVOLVED IN erythrocyte differentiation (ortholog); iron ion transport (ortholog); one-carbon metabolic process (ortholog); ASSOCIATED WITH Animal Disease Models (ortholog); Colorectal Neoplasms (ortholog); lung adenocarcinoma (ortholog); FOUND IN membrane (inferred); mitochondrial inner membrane (inferred); mitochondrial membrane (inferred) | NW_004936609 | 727621 | 754806 | Squirrel | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14285736 | SFXN1 | sideroflexin 1 | ENCODES a protein that exhibits L-alanine transmembrane transporter activity (ortholog); L-serine transmembrane transporter activity (ortholog); INVOLVED IN erythrocyte differentiation (ortholog); iron ion transport (ortholog); L-alanine transport (ortholog); ASSOCIATED WITH Animal Disease Models (o rtholog); Colorectal Neoplasms (ortholog); lung adenocarcinoma (ortholog); FOUND IN mitochondrial inner membrane (ortholog); INTERACTS WITH deoxynivalenol | | | | Pig | 34 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 155247434 | sfxn1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18734376 | SFXN1 | sideroflexin 1 | ENCODES a protein that exhibits L-alanine transmembrane transporter activity (inferred); L-serine transmembrane transporter activity (inferred); monoatomic ion transmembrane transporter activity (inferred); INVOLVED IN erythrocyte differentiation (ortholog); iron ion transport (ortholog); one-carbon metabolic process (ortholog); ASSOCIATED WITH Animal Disease Models (ortholog); Colorectal Neoplasms (ortholog); lung adenocarcinoma (ortholog); FOUND IN membrane (inferred); mitochondrial inner membrane (inferred); mitochondrial membrane (inferred) | | | | Green Monkey | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18903842 | Sfxn1 | sideroflexin 1 | ENCODES a protein that exhibits L-alanine transmembrane transporter activity (inferred); L-serine transmembrane transporter activity (inferred); monoatomic ion transmembrane transporter activity (inferred); INVOLVED IN erythrocyte differentiation (ortholog); iron ion transport (ortholog); one-carbon metabolic process (ortholog); ASSOCIATED WITH Animal Disease Models (ortholog); Colorectal Neoplasms (ortholog); lung adenocarcinoma (ortholog); FOUND IN membrane (inferred); mitochondrial inner membrane (inferred); mitochondrial membrane (inferred) | | | | Naked Mole-Rat | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626112792 | Sfxn1 | sideroflexin 1 | ENCODES a protein that exhibits L-alanine transmembrane transporter activity (ortholog); L-serine transmembrane transporter activity (ortholog); INVOLVED IN erythrocyte differentiation (ortholog); iron ion transport (ortholog); L-alanine transport (ortholog); ASSOCIATED WITH Animal Disease Models (o rtholog); Colorectal Neoplasms (ortholog); lung adenocarcinoma (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog) | | | | Black Rat | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14376646 | Sfxn1-3 | | | | | | Fly | | symbol | gene, null |
| 155247435 | sfxn1.L | | | | | | African Clawed Frog | | symbol | gene, null |