| 1343626 | SRSF2 | serine and arginine rich splicing factor 2 | The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is ric h in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding the same protein and one non-coding transcript variant have been found for this gene. In addition, a pseudogene of this gene has been found on chromosome 11. [provided by RefSeq, Sep 2010] | 17 | 76734115 | 76737411 | Human | 276 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1359422 | Srsf2 | serine and arginine rich splicing factor 2 | ENCODES a protein that exhibits protein kinase C binding; pre-mRNA binding (ortholog); INVOLVED IN response to vitamin E; regulation of alternative mRNA splicing, via spliceosome (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH acute myeloid leukemia (ortholog); Animal Mammary Neopla sms (ortholog); carcinoma (ortholog); FOUND IN interchromatin granule; nuclear speck; perichromatin fibrils; INTERACTS WITH (R,R,R)-alpha-tocopherol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 10 | 102550962 | 102554200 | Rat | 199 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1553658 | Srsf2 | serine and arginine-rich splicing factor 2 | The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is ric h in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. [provided by RefSeq, Sep 2010] | 11 | 116740723 | 116744511 | Mouse | 239 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 12288945 | SRSF2 | serine and arginine rich splicing factor 2 | ENCODES a protein that exhibits protein kinase C binding (ortholog); INVOLVED IN regulation of alternative mRNA splicing, via spliceosome (ortholog); response to vitamin E (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH acute myeloid leukemia (ortholog); Animal Mammary Neoplasms (or tholog); carcinoma (ortholog); FOUND IN interchromatin granule (ortholog); nuclear speck (ortholog); nucleoplasm (ortholog) | 9 | 4028414 | 4032371 | Dog | 54 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 13962740 | SRSF2 | serine and arginine rich splicing factor 2 | ENCODES a protein that exhibits pre-mRNA binding (ortholog); protein kinase C binding (ortholog); INVOLVED IN regulation of alternative mRNA splicing, via spliceosome (ortholog); response to vitamin E (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH acute myeloid leukemia (ortholog); Animal Mammary Neoplasms (ortholog); carcinoma (ortholog); FOUND IN interchromatin granule (ortholog); nuclear speck (ortholog); perichromatin fibrils (ortholog) | | | | Pig | 57 | old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1354010 | SCAF11 | SR-related CTD associated factor 11 | Enables RNA binding activity. Involved in spliceosomal complex assembly. Located in nuclear body and nucleolus. [provided by Alliance of Genome Resources, Jul 2025] | 12 | 45919131 | 45992059 | Human | 102 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1598325 | Scaf11 | SR-related CTD-associated factor 11 | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN RNA splicing (ortholog); RNA splicing, via transesterification reactions (ortholog); spliceosomal complex assembly (ortholog); FOUND IN nuclear body (ortholog); nucleolus (ortholog); nucleoplasm (o rtholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aristolochic acids; bisphenol A | 7 | 129450872 | 129503280 | Rat | 101 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 18923096 | Scaf11 | SR-related CTD associated factor 11 | ENCODES a protein that exhibits metal ion binding (inferred); RNA binding (inferred); zinc ion binding (inferred); INVOLVED IN RNA splicing (ortholog); RNA splicing, via transesterification reactions (ortholog); FOUND IN nuclear body (ortholog); nucleolus (ortholog); nucleoplasm (ortholog) | | | | Naked Mole-Rat | 11 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 1316976 | ARL6IP4 | ARF like GTPase 6 interacting protein 4 | Enables identical protein binding activity. Predicted to be involved in RNA splicing. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Jul 2025] | 12 | 122980233 | 122982909 | Human | 74 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1602488 | RSRC1 | arginine and serine rich coiled-coil 1 | This gene encodes a member of the serine and arginine rich-related protein family. The encoded protein is involved in both constitutive and alternative mRNA splicing. This gene may be associated with schizophrenia. A pseudogene of this gene is located on chromosome 9. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012] | 3 | 158110089 | 158545730 | Human | 130 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1602725 | SRSF8 | serine and arginine rich splicing factor 8 | This gene encodes a member of a family of proteins containing a ribonucleoprotein (RNP)-type RNA binding motif and a carboxyl-terminal arginine-serine-rich (RS) domain. The encoded protein functions as a pre-mRNA splicing factor. There is a pseudogene for this gene on chromosome 7. Alternative splic ing results in multiple transcript variants. [provided by RefSeq, Jun 2013] | 11 | 95066877 | 95071225 | Human | 47 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1619117 | Scaf11 | SR-related CTD-associated factor 11 | Predicted to be involved in spliceosomal complex assembly. Predicted to be located in nuclear body and nucleolus. Is expressed in cerebral cortex ventricular layer; diencephalon lateral wall ventricular layer; heart ventricle; midbrain ventricular layer; and telencephalon ventricular layer. Ortholog ous to human SCAF11 (SR-related CTD associated factor 11). [provided by Alliance of Genome Resources, Jul 2025] | 15 | 96309580 | 96358695 | Mouse | 105 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 12267475 | SCAF11 | SR-related CTD associated factor 11 | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN RNA splicing (inferred); RNA splicing, via transesterification reactions (inferred); spliceosomal complex assembly (inferred); FOUND IN nuclear body (inferred); nucleolus (inferred); nucleoplasm (i nferred) | 27 | 8343501 | 8396735 | Dog | 12 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 1318997 | TNPO3 | transportin 3 | The protein encoded by this gene is a nuclear import receptor for serine/arginine-rich (SR) proteins such as the splicing factors SFRS1 and SFRS2. The encoded protein has also been shown to be involved in HIV-1 infection, apparently through interaction with the HIV-1 capsid protein. Several protein-coding and non-coding transcript variants have been found for this gene. [provided by RefSeq, Apr 2020] | 7 | 128954185 | 129056193 | Human | 159 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 16552147 | AC004870.1 | splicing factor, arginine/serine-rich 2B (SFRS2B) pseudogene | | | | | Human | | name | gene, processed_pseudogene |