| 1309916 | Sall1 | spalt-like transcription factor 1 | ENCODES a protein that exhibits beta-catenin binding (ortholog); chromatin binding (ortholog); cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN adrenal gland development (ortholog); branching involved in ureteric bud morphogenesis (ortholog); embryonic digestive tract deve lopment (ortholog); ASSOCIATED WITH CAKUT (ortholog); chronic kidney disease (ortholog); Congenital Abnormalities (ortholog); FOUND IN chromocenter (ortholog); cytoplasm (ortholog); heterochromatin (ortholog); INTERACTS WITH 17beta-estradiol; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 19 | 34179316 | 34196278 | Rat | 237 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1320515 | SALL1 | spalt like transcription factor 1 | The protein encoded by this gene is a zinc finger transcriptional repressor and may be part of the NuRD histone deacetylase complex (HDAC). Defects in this gene are a cause of Townes-Brocks syndrome (TBS) as well as bronchio-oto-renal syndrome (BOR). Two transcript variants encoding different isofor ms have been found for this gene. [provided by RefSeq, Jul 2008] | 16 | 51135982 | 51152334 | Human | 414 | symbol , old_gene_name , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1320516 | Sall1 | spalt like transcription factor 1 | Enables several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II-specific DNA-binding transcription factor binding activity; and cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including negativ e regulation of ectoderm development; nephron epithelium morphogenesis; and nervous system development. Acts upstream of or within several processes, including kidney development; limb morphogenesis; and nervous system development. Located in heterochromatin and nucleus. Part of NuRD complex. Is expressed in several structures, including autopod; central nervous system; embryo mesenchyme; metanephros; and sensory organ. Used to study Townes-Brocks syndrome. Human ortholog(s) of this gene implicated in Townes-Brocks syndrome; middle lobe syndrome; and renal Wilms' tumor. Orthologous to human SALL1 (spalt like transcription factor 1). [provided by Alliance of Genome Resources, Jul 2025] | 8 | 89753867 | 89770790 | Mouse | 288 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8703235 | Sall1 | spalt like transcription factor 1 | ENCODES a protein that exhibits beta-catenin binding (ortholog); chromatin binding (ortholog); cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN adrenal gland development (ortholog); branching involved in ureteric bud morphogenesis (ortholog); embryonic digestive tract deve lopment (ortholog); ASSOCIATED WITH CAKUT (ortholog); chronic kidney disease (ortholog); Congenital Abnormalities (ortholog); FOUND IN chromocenter (ortholog); cytoplasm (ortholog); heterochromatin (ortholog) | NW_004955433 | 9146074 | 9161171 | Chinchilla | 83 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11960818 | SALL1 | spalt like transcription factor 1 | ENCODES a protein that exhibits chromatin binding (ortholog); cis-regulatory region sequence-specific DNA binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN branching involved in ureteric bud morphogenesis (ortholog); forelimb morphogenesis (ortholog); hindlimb morphogene sis (ortholog); ASSOCIATED WITH CAKUT (ortholog); chronic kidney disease (ortholog); Congenital Abnormalities (ortholog); FOUND IN NuRD complex (ortholog) | 16 | 31396399 | 31412753 | Bonobo | 92 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12053775 | SALL1 | spalt like transcription factor 1 | ENCODES a protein that exhibits chromatin binding (ortholog); cis-regulatory region sequence-specific DNA binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN branching involved in ureteric bud morphogenesis (ortholog); forelimb morphogenesis (ortholog); hindlimb morphogene sis (ortholog); ASSOCIATED WITH CAKUT (ortholog); chronic kidney disease (ortholog); Congenital Abnormalities (ortholog); FOUND IN NuRD complex (ortholog) | 2 | 64242742 | 64260021 | Dog | 93 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12649604 | Sall1 | spalt like transcription factor 1 | ENCODES a protein that exhibits chromatin binding (ortholog); cis-regulatory region sequence-specific DNA binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN branching involved in ureteric bud morphogenesis (ortholog); forelimb morphogenesis (ortholog); hindlimb morphogene sis (ortholog); ASSOCIATED WITH CAKUT (ortholog); chronic kidney disease (ortholog); Congenital Abnormalities (ortholog); FOUND IN NuRD complex (ortholog) | NW_004936475 | 4106663 | 4121356 | Squirrel | 95 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18930663 | Sall1 | spalt like transcription factor 1 | ENCODES a protein that exhibits beta-catenin binding (ortholog); chromatin binding (ortholog); cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN adrenal gland development (ortholog); branching involved in ureteric bud morphogenesis (ortholog); embryonic digestive tract deve lopment (ortholog); ASSOCIATED WITH CAKUT (ortholog); chronic kidney disease (ortholog); Congenital Abnormalities (ortholog); FOUND IN chromocenter (ortholog); cytoplasm (ortholog); NuRD complex (ortholog) | | | | Naked Mole-Rat | 88 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155259639 | sall1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18412609 | SALL1 | spalt like transcription factor 1 | ENCODES a protein that exhibits chromatin binding (ortholog); cis-regulatory region sequence-specific DNA binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN branching involved in ureteric bud morphogenesis (ortholog); forelimb morphogenesis (ortholog); hindlimb morphogene sis (ortholog); ASSOCIATED WITH CAKUT (ortholog); chronic kidney disease (ortholog); Congenital Abnormalities (ortholog); FOUND IN NuRD complex (ortholog) | | | | Green Monkey | 94 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14079951 | SALL1 | spalt like transcription factor 1 | ENCODES a protein that exhibits chromatin binding (ortholog); cis-regulatory region sequence-specific DNA binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN branching involved in ureteric bud morphogenesis (ortholog); forelimb morphogenesis (ortholog); hindlimb morphogene sis (ortholog); ASSOCIATED WITH CAKUT (ortholog); chronic kidney disease (ortholog); Congenital Abnormalities (ortholog); FOUND IN NuRD complex (ortholog) | | | | Pig | 93 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155259647 | sall1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 626468706 | sall1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405865290 | sall1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405860448 | sall1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405863884 | sall1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405857632 | sall1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 617301366 | SALL1-AS1 | SALL1 antisense RNA 1 | | | | | Human | | symbol , GTEx , COSMIC , name , Human Proteome Map | gene, ncrna |
| 126781694 | Sall1em1Nips | spalt-like transcription factor 1; CRISPR/Cas9 induced mutant 1, Nips | Sall1 mutation was induced by injecting a mix of two pX330 expressing Cas9 and sgRNA targeting the sequence into Crlj:WI rat embryos. The resulting mutation is a 4456-bp deletion in exon 2 to 3. Homozygous Sall1 knocked-out rats had the anephric phenotype at E21.5, and died at postnatal Day-1. | | | | Rat | | symbol , description | gene, allele |
| 126781695 | Sall1tm4(tdTomato)Nips | spalt-like transcription factor 1; targeted mutant 4, Nips | Targeting vector was designed to replace 2nd and 3rd exons encoding DNA-binding domain of Sall1 locus with tdTomato. The vector was introduced into WDB/Nips-ES1/Nips (RGD ID:10054010) embryonic stem cells by electroporation. Founder animals were backcrossed to C rlj:WI. Homozygous Sall1 knocked-in rats had the anephric phenotype at E21.5, and died at postnatal Day-1. | | | | Rat | | symbol , description | gene, allele |
| 16563167 | AC009166.1 | novel transcript, antisense to SALL1 | | | | | Human | | name | gene, lncrna |
| 5130644 | SALL4P3 | spalt like transcription factor 4 pseudogene 3 | | 16 | 20155582 | 20158626 | Human | | old_gene_name | gene, pseudo, INFERRED [RefSeq] |
| 1350763 | SALL1P1 | spalt like transcription factor 1 pseudogene 1 | | X | 49663736 | 49668690 | Human | | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, pseudo, INFERRED [RefSeq] |
| 2299396 | Gm3134 | predicted gene 3134 | Is expressed in urinary system. [provided by Alliance of Genome Resources, Jul 2025] | 8 | 89767871 | 89797647 | Mouse | | old_gene_symbol | gene, ncrna, VALIDATED [RefSeq] |