| 62254 | S1pr3 | sphingosine-1-phosphate receptor 3 | This gene encodes a member of the G-protein coupled receptor 1 family. The encoded protein is a receptor for the lysophospholipid sphingosine 1-phosphate. The gene product functions in endothelial cells and is involved in vascular and heart development. The gene product mediates HDL and HDL-associat ed lysophospholipid-induced vasorelaxation, and it coordinates with other lysophospholipid receptors in the process of angiogenesis. [provided by RefSeq, Jan 2010] | 13 | 51562654 | 51576833 | Mouse | 223 | symbol , PhenoGen | gene, protein-coding, REVIEWED [RefSeq] |
| 1352881 | S1PR3 | sphingosine-1-phosphate receptor 3 | This gene encodes a member of the EDG family of receptors, which are G protein-coupled receptors. This protein has been identified as a functional receptor for sphingosine 1-phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function. [provided by RefSeq , Jul 2008] | 9 | 88990863 | 89005155 | Human | 179 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1583843 | S1pr3 | sphingosine-1-phosphate receptor 3 | ENCODES a protein that exhibits integrin binding (ortholog); INVOLVED IN adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); inflammatory response (ortholog); negative regulation of establishment of endothelial barrier (ortholog); PARTICIPATES IN sphingosine 1-phosp hate signaling pathway; FOUND IN plasma membrane (ortholog); presynapse (ortholog); INTERACTS WITH acetamide; aldehydo-D-glucose; ammonium chloride | 17 | 13932773 | 13946213 | Rat | 170 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 9041298 | S1pr3 | sphingosine-1-phosphate receptor 3 | ENCODES a protein that exhibits integrin binding (ortholog); INVOLVED IN adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); inflammatory response (ortholog); negative regulation of establishment of endothelial barrier (ortholog); PARTICIPATES IN sphingosine 1-phosp hate signaling pathway; FOUND IN plasma membrane (ortholog); presynapse (ortholog) | NW_004955515 | 3024258 | 3035996 | Chinchilla | 11 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11736144 | S1PR3 | sphingosine-1-phosphate receptor 3 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); integrin binding (inferred); sphingosine-1-phosphate receptor activity (inferred); INVOLVED IN adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); inflammatory response (ortholog); Notch signaling pathway (ortholog); PARTICIPATES IN sphingosine 1-phosphate signaling pathway; FOUND IN membrane (inferred); plasma membrane (inferred); presynapse (inferred) | 9 | 60080189 | 60094311 | Bonobo | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12128577 | S1PR3 | sphingosine-1-phosphate receptor 3 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); integrin binding (inferred); sphingosine-1-phosphate receptor activity (inferred); INVOLVED IN adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); inflammatory response (ortholog); Notch signaling pathway (ortholog); PARTICIPATES IN sphingosine 1-phosphate signaling pathway; FOUND IN membrane (inferred); plasma membrane (inferred); presynapse (inferred) | 1 | 97102708 | 97107611 | Dog | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12441009 | S1pr3 | sphingosine-1-phosphate receptor 3 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); integrin binding (inferred); sphingosine-1-phosphate receptor activity (inferred); INVOLVED IN adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); inflammatory response (ortholog); Notch signaling pathway (ortholog); PARTICIPATES IN sphingosine 1-phosphate signaling pathway; FOUND IN presynapse (ortholog) | NW_004937645 | 39690 | 40790 | Squirrel | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 329329170 | s1pr3 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18925074 | S1pr3 | sphingosine-1-phosphate receptor 3 | ENCODES a protein that exhibits integrin binding (ortholog); INVOLVED IN adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); inflammatory response (ortholog); negative regulation of establishment of endothelial barrier (ortholog); PARTICIPATES IN sphingosine 1-phosp hate signaling pathway; FOUND IN presynapse (ortholog) | | | | Naked Mole-Rat | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18380773 | S1PR3 | sphingosine-1-phosphate receptor 3 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); integrin binding (inferred); sphingosine-1-phosphate receptor activity (inferred); INVOLVED IN adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); inflammatory response (ortholog); Notch signaling pathway (ortholog); PARTICIPATES IN sphingosine 1-phosphate signaling pathway; FOUND IN membrane (inferred); plasma membrane (inferred); presynapse (inferred) | | | | Green Monkey | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625839279 | S1pr3 | sphingosine-1-phosphate receptor 3 | ENCODES a protein that exhibits integrin binding (ortholog); INVOLVED IN adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); inflammatory response (ortholog); negative regulation of establishment of endothelial barrier (ortholog); PARTICIPATES IN sphingosine 1-phosp hate signaling pathway; FOUND IN plasma membrane (ortholog); presynapse (ortholog) | | | | Black Rat | 11 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13911898 | S1PR3 | sphingosine-1-phosphate receptor 3 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); integrin binding (inferred); sphingosine-1-phosphate receptor activity (inferred); INVOLVED IN adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); inflammatory response (ortholog); Notch signaling pathway (ortholog); PARTICIPATES IN sphingosine 1-phosphate signaling pathway; FOUND IN membrane (inferred); plasma membrane (inferred); presynapse (inferred) | | | | Pig | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 288083212 | s1pr3.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 329332963 | s1pr3.S | | | | | | African Clawed Frog | | symbol | gene, null |