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30 records found for search term Ripk1
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
1310158Ripk1receptor interacting serine/threonine kinase 1ENCODES a protein that exhibits death receptor binding; protein-containing complex binding; death domain binding (ortholog); INVOLVED IN positive regulation of necroptotic process; positive regulation of neuron apoptotic process; positive regulation of non-canonical NF-kappaB signal transduction; PA173104498331077167Rat464symbol , PhenoGengene, protein-coding, PROVISIONAL [RefSeq]
1320896RIPK1receptor interacting serine/threonine kinase 1This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein plays a role in inflammation and cell death in response to tissue damage, pathogen recognition, and as part of developmental regulation. RIPK1630639673115187Human505symbol , COSMIC , description , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1320897Ripk1receptor (TNFRSF)-interacting serine-threonine kinase 1Enables protein homodimerization activity; protein serine/threonine kinase activity; and signaling adaptor activity. Involved in several processes, including necroptotic signaling pathway; negative regulation of necroptotic process; and regulation of signal transduction. Acts upstream of or within s133418107234219153Mouse516symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
8768515Ripk1receptor interacting serine/threonine kinase 1ENCODES a protein that exhibits death domain binding (ortholog); death receptor binding (ortholog); identical protein binding (ortholog); INVOLVED IN activation of protein kinase activity (ortholog); amyloid fibril formation (ortholog); apoptotic process (ortholog); PARTICIPATES IN ceramide signalinNW_0049554651012790710167895Chinchilla169symbolgene, protein-coding, MODEL [RefSeq]
11685980RIPK1receptor interacting serine/threonine kinase 1ENCODES a protein that exhibits death receptor binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN activation of protein kinase activity (ortholog); necroptotic process (ortholog); negative regulation of extrinsic apoptotic signaling pathway (ortholog); PARTICIPATES IN cer628938022943162Bonobo184symbolgene, protein-coding, MODEL [RefSeq]
12106239RIPK1receptor interacting serine/threonine kinase 1ENCODES a protein that exhibits death receptor binding (ortholog); protein-containing complex binding (ortholog); signaling adaptor activity (ortholog); INVOLVED IN activation of protein kinase activity (ortholog); cellular response to growth factor stimulus (ortholog); cellular response to hydrogen3533677963407631Dog179symbolgene, protein-coding, MODEL [RefSeq]
12621197Ripk1receptor interacting serine/threonine kinase 1ENCODES a protein that exhibits death receptor binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN activation of protein kinase activity (ortholog); necroptotic process (ortholog); negative regulation of extrinsic apoptotic signaling pathway (ortholog); PARTICIPATES IN cerNW_00493653493263079361943Squirrel180symbolgene, protein-coding, MODEL [RefSeq]
14273646RIPK1receptor interacting serine/threonine kinase 1ENCODES a protein that exhibits death receptor binding (ortholog); protein kinase activity (ortholog); protein-containing complex binding (ortholog); INVOLVED IN activation of protein kinase activity (ortholog); amyloid fibril formation (ortholog); apoptotic process (ortholog); PARTICIPATES IN ceramPig196symbolgene, protein-coding, MODEL [RefSeq]
18734175RIPK1receptor interacting serine/threonine kinase 1ENCODES a protein that exhibits death receptor binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN activation of protein kinase activity (ortholog); necroptotic process (ortholog); negative regulation of extrinsic apoptotic signaling pathway (ortholog); PARTICIPATES IN cerGreen Monkey180symbolgene, protein-coding, MODEL [RefSeq]
18904721Ripk1receptor interacting serine/threonine kinase 1ENCODES a protein that exhibits death receptor binding (ortholog); protein kinase activity (ortholog); protein-containing complex binding (ortholog); INVOLVED IN activation of protein kinase activity (ortholog); amyloid fibril formation (ortholog); apoptotic process (ortholog); PARTICIPATES IN ceramNaked Mole-Rat188symbolgene, protein-coding, MODEL [RefSeq]
155234990ripk1Tropical Clawed Frogsymbolgene, null
625918053Ripk1receptor interacting serine/threonine kinase 1ENCODES a protein that exhibits death domain binding (ortholog); death receptor binding (ortholog); identical protein binding (ortholog); INVOLVED IN activation of protein kinase activity (ortholog); amyloid fibril formation (ortholog); apoptotic process (ortholog); PARTICIPATES IN ceramide signalinBlack Rat169symbolgene, protein-coding, MODEL [RefSeq]
155247225ripk1.LAfrican Clawed Frogsymbolgene, null
155234991ripk1.SAfrican Clawed Frogsymbolgene, null
1311271Ippkinositol-pentakisphosphate 2-kinaseENCODES a protein that exhibits inositol-1,3,4,5,6-pentakisphosphate 2-kinase activity; molecular adaptor activity (ortholog); INVOLVED IN positive regulation of transcription of nucleolar large rRNA by RNA polymerase I (ortholog); PARTICIPATES IN inositol metabolic pathway; inositol phosphate metab171539669115441648Rat66old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
16566329AL031963.3novel transcript, antisense to RIPK1Humannamegene, lncrna
1322238CraddCASP2 and RIPK1 domain containing adaptor with death domainPredicted to enable death domain binding activity; protease binding activity; and protein-macromolecule adaptor activity. Acts upstream of or within positive regulation of apoptotic signaling pathway. Located in cytoplasm and nucleus. Is expressed in several structures, including branchial arch; cen109501060195160000Mouse138old_gene_name , name , descriptiongene, protein-coding, VALIDATED [RefSeq]
12370107CRADDCASP2 and RIPK1 domain containing adaptor with death domainENCODES a protein that exhibits death domain binding (inferred); protease binding (inferred); protein-macromolecule adaptor activity (inferred); INVOLVED IN positive regulation of apoptotic signaling pathway (ortholog); PARTICIPATES IN ceramide signaling pathway; ASSOCIATED WITH arrhythmogenic right153387360034052498Dog41namegene, protein-coding, MODEL [RefSeq]
153286778CRADDCASP2 and RIPK1 domain containing adaptor with death domainGreen Monkeynamegene, protein-coding
616362809CRADDCASP2 and RIPK1 domain containing adaptor with death domainENCODES a protein that exhibits death domain binding (inferred); protease binding (inferred); protein-macromolecule adaptor activity (inferred); INVOLVED IN apoptotic signaling pathway (inferred); cellular response to mechanical stimulus (inferred); DNA damage response, signal transduction by p53 clGreen Monkey14namegene, protein-coding
16557270AC117392.1CASP2 and RIPK1 domain containing adaptor with death domain (CRADD) pseudogeneHumannamegene, processed_pseudogene
1311010CraddCARD and death domain containing adaptor proteinENCODES a protein that exhibits death domain binding (ortholog); protease binding (ortholog); protein-macromolecule adaptor activity (ortholog); INVOLVED IN apoptotic signaling pathway (ortholog); cellular response to mechanical stimulus (ortholog); DNA damage response, signal transduction by p53 cl73182713131839796Rat110old_gene_namegene, protein-coding, PROVISIONAL [RefSeq]
1322237CRADDCARD and death domain containing adaptor proteinThis gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. 129367737593894840Human154old_gene_name , descriptiongene, protein-coding, REVIEWED [RefSeq]
11767656CRADDCARD and death domain containing adaptor proteinENCODES a protein that exhibits death domain binding (ortholog); protease binding (ortholog); protein-macromolecule adaptor activity (ortholog); INVOLVED IN apoptotic signaling pathway (ortholog); cellular response to mechanical stimulus (ortholog); DNA damage response, signal transduction by p53 cl129122081391593799Bonobo28old_gene_namegene, protein-coding, MODEL [RefSeq]
12720978CraddCARD and death domain containing adaptor proteinENCODES a protein that exhibits death domain binding (inferred); protease binding (inferred); protein-macromolecule adaptor activity (inferred); INVOLVED IN positive regulation of apoptotic signaling pathway (ortholog); PARTICIPATES IN ceramide signaling pathway; ASSOCIATED WITH arrhythmogenic rightNW_0049365071007734510264705Squirrel40old_gene_namegene, protein-coding, MODEL [RefSeq]
13959151CRADDCARD and death domain containing adaptor proteinENCODES a protein that exhibits insulin-like growth factor receptor binding (ortholog); phosphorylation-dependent protein binding (ortholog); ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN cellular response to hormone stimulus (ortholog); growth hormone receptor signaling pPig52old_gene_namegene, protein-coding, MODEL [RefSeq]
18359369CRADDCARD and death domain containing adaptor proteinENCODES a protein that exhibits protein-macromolecule adaptor activity (ortholog); INVOLVED IN apoptotic signaling pathway (ortholog); DNA damage response, signal transduction by p53 class mediator (ortholog); positive regulation of apoptotic process (ortholog); PARTICIPATES IN ceramide signaling paGreen Monkey31old_gene_namegene, protein-coding, MODEL [RefSeq]
18900877CraddCARD and death domain containing adaptor proteinENCODES a protein that exhibits protein-macromolecule adaptor activity (ortholog); INVOLVED IN apoptotic signaling pathway (ortholog); DNA damage response, signal transduction by p53 class mediator (ortholog); positive regulation of apoptotic signaling pathway (ortholog); PARTICIPATES IN ceramide siNaked Mole-Rat35old_gene_namegene, protein-coding, MODEL [RefSeq]
626038337CraddCARD and death domain containing adaptor proteinENCODES a protein that exhibits death domain binding (ortholog); protease binding (ortholog); protein-macromolecule adaptor activity (ortholog); INVOLVED IN apoptotic signaling pathway (ortholog); cellular response to mechanical stimulus (ortholog); DNA damage response, signal transduction by p53 clBlack Rat28old_gene_namegene, protein-coding, MODEL [RefSeq]
38615537CRADDP1CRADD pseudogene 13156987772156988739Humanold_gene_namegene, pseudo, INFERRED [RefSeq]