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15 records found for search term Rapgef5
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
1343059RAPGEF5Rap guanine nucleotide exchange factor 5Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS a72211823622357154Human114symbol , COSMIC , description , Human Proteome Mapgene, protein-coding, VALIDATED [RefSeq]
1557976Rapgef5Rap guanine nucleotide exchange factor (GEF) 5Predicted to enable GTP-dependent protein binding activity and guanyl-nucleotide exchange factor activity. Predicted to be involved in Ras protein signal transduction. Predicted to be located in nuclear body. Predicted to be active in plasma membrane. Is expressed in several structures, including al12117480146117723472Mouse117symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
1561668Rapgef5Rap guanine nucleotide exchange factor 5ENCODES a protein that exhibits GTP-dependent protein binding (ortholog); guanyl-nucleotide exchange factor activity (ortholog); INVOLVED IN ganglion development (inferred); intracellular signal transduction (inferred); positive regulation of smooth muscle cell migration (inferred); ASSOCIATED WITH 6144588162144822908Rat112symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
8727359Rapgef5Rap guanine nucleotide exchange factor 5ENCODES a protein that exhibits GTP-dependent protein binding (ortholog); guanyl-nucleotide exchange factor activity (ortholog); ASSOCIATED WITH amphetamine abuse (ortholog); dilated cardiomyopathy 1A (ortholog); FOUND IN nuclear body (ortholog); nucleoplasm (ortholog); nucleus (ortholog)NW_0049554102452574824716151Chinchilla8symbolgene, protein-coding, MODEL [RefSeq]
11768650RAPGEF5Rap guanine nucleotide exchange factor 5ENCODES a protein that exhibits GTP-dependent protein binding (ortholog); INVOLVED IN Ras protein signal transduction (inferred); small GTPase-mediated signal transduction (inferred); ASSOCIATED WITH amphetamine abuse (ortholog); dilated cardiomyopathy 1A (ortholog); FOUND IN nuclear body (ortholog)72280685523047663Bonobo13symbolgene, protein-coding, MODEL [RefSeq]
12429763RAPGEF5Rap guanine nucleotide exchange factor 5ENCODES a protein that exhibits GTP-dependent protein binding (ortholog); INVOLVED IN intracellular signal transduction (inferred); small GTPase-mediated signal transduction (inferred); ASSOCIATED WITH amphetamine abuse (ortholog); dilated cardiomyopathy 1A (ortholog); FOUND IN nuclear body (inferre143597939336208849Dog16symbolgene, protein-coding, MODEL [RefSeq]
12639629Rapgef5Rap guanine nucleotide exchange factor 5ENCODES a protein that exhibits GTP-dependent protein binding (ortholog); INVOLVED IN intracellular signal transduction (inferred); Ras protein signal transduction (inferred); small GTPase-mediated signal transduction (inferred); ASSOCIATED WITH amphetamine abuse (ortholog); dilated cardiomyopathy 1NW_00493654678607958051351Squirrel14symbolgene, protein-coding, MODEL [RefSeq]
155249413rapgef5Tropical Clawed Frogsymbolgene, null
18711846RAPGEF5Rap guanine nucleotide exchange factor 5ENCODES a protein that exhibits GTP-dependent protein binding (ortholog); INVOLVED IN Ras protein signal transduction (inferred); small GTPase-mediated signal transduction (inferred); ASSOCIATED WITH amphetamine abuse (ortholog); dilated cardiomyopathy 1A (ortholog); FOUND IN nuclear body (inferred)Green Monkey13symbolgene, protein-coding, MODEL [RefSeq]
625999562Rapgef5Rap guanine nucleotide exchange factor 5ENCODES a protein that exhibits GTP-dependent protein binding (ortholog); guanyl-nucleotide exchange factor activity (ortholog); ASSOCIATED WITH amphetamine abuse (ortholog); dilated cardiomyopathy 1A (ortholog); FOUND IN nuclear body (ortholog); nucleoplasm (ortholog); nucleus (ortholog)Black Rat8symbolgene, protein-coding, MODEL [RefSeq]
18928080Rapgef5Rap guanine nucleotide exchange factor 5ENCODES a protein that exhibits GTP-dependent protein binding (ortholog); INVOLVED IN intracellular signal transduction (inferred); Ras protein signal transduction (inferred); small GTPase-mediated signal transduction (inferred); ASSOCIATED WITH amphetamine abuse (ortholog); dilated cardiomyopathy 1Naked Mole-Rat14symbolgene, protein-coding, MODEL [RefSeq]
13877087RAPGEF5Rap guanine nucleotide exchange factor 5ENCODES a protein that exhibits GTP-dependent protein binding (ortholog); INVOLVED IN intracellular signal transduction (inferred); small GTPase-mediated signal transduction (inferred); ASSOCIATED WITH amphetamine abuse (ortholog); dilated cardiomyopathy 1A (ortholog); FOUND IN nuclear body (ortholoPig16symbolgene, protein-coding, MODEL [RefSeq]
155246891rapgef5.LAfrican Clawed Frogsymbolgene, null
155242821rapgef5.SAfrican Clawed Frogsymbolgene, null
41038239Rapgef5-ps1Rap guanine nucleotide exchange factor 5, pseudogene 1152566179725668062Ratsymbol , PhenoGengene, pseudo, MODEL [RefSeq]