| 1310705 | Pwp1 | PWP1 homolog, endonuclein | ENCODES a protein that exhibits histone H4K20me3 reader activity (ortholog); INVOLVED IN negative regulation of DNA-templated transcription (ortholog); positive regulation of stem cell differentiation (ortholog); positive regulation of transcription of nucleolar large rRNA by RNA polymerase I (ortho log); FOUND IN nucleolus (ortholog); nucleus (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 4-amino-2,6-dinitrotoluene | 7 | 19870465 | 19886463 | Rat | 81 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, INFERRED [RefSeq] |
| 1553512 | Pwp1 | PWP1 homolog, endonuclein | Enables histone H4K20me3 reader activity and histone chaperone activity. Acts upstream of or within negative regulation of DNA-templated transcription and positive regulation of stem cell differentiation. Located in nucleus. Is expressed in several structures, including brain; neural retina; and tra chea. Orthologous to human PWP1 (PWP1 homolog, endonuclein). [provided by Alliance of Genome Resources, Apr 2025] | 10 | 85707695 | 85724967 | Mouse | 88 | symbol , old_gene_name , PhenoGen , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1605095 | PWP1 | PWP1 homolog, endonuclein | The protein encoded by this gene contains several WD-40 repeats and is found mostly in the nucleus. The expression and localization of this protein are cell cycle dependent. Expression of this gene is upregulated in pancreatic adenocarcinoma. Three transcript variants encoding different isoforms hav e been found for this gene. [provided by RefSeq, Dec 2015] | 12 | 107685799 | 107713162 | Human | 84 | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 8930943 | Pwp1 | PWP1 homolog, endonuclein | ENCODES a protein that exhibits histone H4K20me3 reader activity (ortholog); INVOLVED IN negative regulation of DNA-templated transcription (ortholog); positive regulation of stem cell differentiation (ortholog); positive regulation of transcription of nucleolar large rRNA by RNA polymerase I (ortho log); FOUND IN nucleolus (ortholog); nucleus (ortholog) | NW_004955405 | 41314978 | 41329988 | Chinchilla | 6 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 11990357 | PWP1 | PWP1 homolog, endonuclein | ENCODES a protein that exhibits histone H4K20me3 reader activity (inferred); INVOLVED IN negative regulation of DNA-templated transcription (ortholog); positive regulation of stem cell differentiation (ortholog); FOUND IN chromosome (inferred); nucleolus (inferred); nucleus (inferred) | 12 | 105255755 | 105282519 | Bonobo | 15 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 12296472 | PWP1 | PWP1 homolog, endonuclein | ENCODES a protein that exhibits histone H4K20me3 reader activity (inferred); INVOLVED IN negative regulation of DNA-templated transcription (ortholog); positive regulation of stem cell differentiation (ortholog); FOUND IN chromosome (inferred); nucleolus (inferred); nucleus (inferred) | 10 | 31121411 | 31146791 | Dog | 17 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 12500423 | Pwp1 | PWP1 homolog, endonuclein | ENCODES a protein that exhibits histone H4K20me3 reader activity (inferred); INVOLVED IN negative regulation of DNA-templated transcription (ortholog); positive regulation of stem cell differentiation (ortholog); FOUND IN chromosome (inferred); nucleolus (inferred); nucleus (inferred) | NW_004936492 | 7436137 | 7457709 | Squirrel | 15 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 18930253 | Pwp1 | PWP1 homolog, endonuclein | ENCODES a protein that exhibits histone H4K20me3 reader activity (ortholog); INVOLVED IN negative regulation of DNA-templated transcription (ortholog); positive regulation of stem cell differentiation (ortholog); positive regulation of transcription of nucleolar large rRNA by RNA polymerase I (ortho log); FOUND IN chromosome (inferred); nucleolus (inferred); nucleus (inferred) | | | | Naked Mole-Rat | 12 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 18552026 | PWP1 | PWP1 homolog, endonuclein | ENCODES a protein that exhibits histone H4K20me3 reader activity (inferred); INVOLVED IN negative regulation of DNA-templated transcription (ortholog); positive regulation of stem cell differentiation (ortholog); FOUND IN chromosome (inferred); nucleolus (inferred); nucleus (inferred) | | | | Green Monkey | 15 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 14236991 | PWP1 | PWP1 homolog, endonuclein | ENCODES a protein that exhibits histone H4K20me3 reader activity (inferred); INVOLVED IN negative regulation of DNA-templated transcription (ortholog); positive regulation of stem cell differentiation (ortholog); FOUND IN chromosome (inferred); nucleolus (inferred); nucleus (inferred); INTERACTS WIT H deoxynivalenol | | | | Pig | 18 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 14379191 | PWP1 | | | | | | Yeast | | symbol | gene, null |
| 626080820 | Pwp1 | PWP1 homolog, endonuclein | ENCODES a protein that exhibits histone H4K20me3 reader activity (ortholog); INVOLVED IN negative regulation of DNA-templated transcription (ortholog); positive regulation of stem cell differentiation (ortholog); positive regulation of transcription of nucleolar large rRNA by RNA polymerase I (ortho log); FOUND IN nucleolus (ortholog); nucleus (ortholog) | | | | Black Rat | 6 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 155255548 | pwp1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155255549 | pwp1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 2320392 | Pwp1-ps1 | PWP1 homolog, endonuclein, pseudogene 1 | | 5 | 98279226 | 98283564 | Rat | | symbol , PhenoGen , name | gene, pseudo, MODEL [RefSeq] |
| 1597112 | Pwp1-ps2 | PWP1 homolog, endonuclein, pseudogene 2 | | 1 | 223123051 | 223126816 | Rat | | symbol , PhenoGen , name | gene, pseudo, MODEL [RefSeq] |
| 1316536 | DNAJB11 | DnaJ heat shock protein family (Hsp40) member B11 | This gene encodes a soluble glycoprotein of the endoplasmic reticulum (ER) lumen that functions as a co-chaperone of binding immunoglobulin protein, a 70 kilodalton heat shock protein chaperone required for the proper folding and assembly of proteins in the ER. The encoded protein contains a highly conserved J domain of about 70 amino acids with a characteristic His-Pro-Asp (HPD) motif and may regulate the activity of binding immunoglobulin protein by stimulating ATPase activity. [provided by RefSeq, Mar 2014] | 3 | 186570720 | 186585793 | Human | 248 | old_gene_name | gene, protein-coding, REVIEWED [RefSeq] |
| 1320780 | SDF2L1 | stromal cell derived factor 2 like 1 | Enables misfolded protein binding activity. Involved in chaperone cofactor-dependent protein refolding. Located in endoplasmic reticulum. Part of protein folding chaperone complex. [provided by Alliance of Genome Resources, Apr 2025] | 22 | 21642302 | 21644299 | Human | 205 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 736464 | SSBP1 | single stranded DNA binding protein 1 | SSBP1 is a housekeeping gene involved in mitochondrial biogenesis (Tiranti et al., 1995 [PubMed 7789991]). It is also a subunit of a single-stranded DNA (ssDNA)-binding complex involved in the maintenance of genome stability (Huang et al., 2009) [PubMed 19683501].[supplied by OMIM, Feb 2010] | 7 | 141738321 | 141750488 | Human | 175 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |