| 632281 | Ppp1r9b | protein phosphatase 1, regulatory subunit 9B | ENCODES a protein that exhibits actin binding; actin filament binding; D2 dopamine receptor binding; INVOLVED IN actin filament depolymerization; cellular response to epidermal growth factor stimulus; cellular response to estradiol stimulus; ASSOCIATED WITH Cognitive Dysfunction; Parkinson's disease ; Alzheimer's disease (ortholog); FOUND IN actin cytoskeleton; cytoplasmic side of dendritic spine plasma membrane; dendritic spine; INTERACTS WITH (S)-amphetamine; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 10 | 80434888 | 80450919 | Rat | 224 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 733635 | PPP1R9B | protein phosphatase 1 regulatory subunit 9B | This gene encodes a scaffold protein that functions as a regulatory subunit of protein phosphatase 1a. Expression of this gene is particularly high in dendritic spines, suggesting that the encoded protein may play a role in receiving signals from the central nervous system. The encoded protein has p utative tumor suppressor function and decreased expression has been observed in tumors. [provided by RefSeq, Feb 2014] | 17 | 50133737 | 50150677 | Human | 250 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1552611 | Ppp1r9b | protein phosphatase 1, regulatory subunit 9B | Predicted to enable several functions, including D2 dopamine receptor binding activity; enzyme binding activity; and transmembrane transporter binding activity. Involved in cellular response to morphine; regulation of opioid receptor signaling pathway; and regulation of postsynapse assembly. Acts up stream of or within several processes, including actin filament organization; calcium-mediated signaling; and dendrite development. Located in cortical actin cytoskeleton and filopodium. Is expressed in several structures, including alimentary system; brain; connective tissue; genitourinary system; and hemolymphoid system. Orthologous to human PPP1R9B (protein phosphatase 1 regulatory subunit 9B). [provided by Alliance of Genome Resources, Jul 2025] | 11 | 94882038 | 94897724 | Mouse | 302 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8890650 | Ppp1r9b | protein phosphatase 1 regulatory subunit 9B | ENCODES a protein that exhibits actin binding (ortholog); actin filament binding (ortholog); D2 dopamine receptor binding (ortholog); INVOLVED IN actin filament depolymerization (ortholog); actin filament organization (ortholog); calcium-mediated signaling (ortholog); ASSOCIATED WITH Alzheimer's dis ease (ortholog); Cognitive Dysfunction (ortholog); Colorectal Neoplasms (ortholog); FOUND IN actin cytoskeleton (ortholog); cortical actin cytoskeleton (ortholog); cytoplasm (ortholog) | NW_004955451 | 11516548 | 11530263 | Chinchilla | 105 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11890018 | PPP1R9B | protein phosphatase 1 regulatory subunit 9B | ENCODES a protein that exhibits actin binding (ortholog); actin filament binding (ortholog); D2 dopamine receptor binding (ortholog); INVOLVED IN actin filament depolymerization (ortholog); actin filament organization (ortholog); calcium-mediated signaling (ortholog); ASSOCIATED WITH Alzheimer's dis ease (ortholog); Cognitive Dysfunction (ortholog); Colorectal Neoplasms (ortholog); FOUND IN actin cytoskeleton (ortholog); cytoplasmic side of dendritic spine plasma membrane (ortholog); dendritic spine (ortholog) | 17 | 44224007 | 44240906 | Bonobo | 117 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12237755 | PPP1R9B | protein phosphatase 1 regulatory subunit 9B | ENCODES a protein that exhibits actin binding (ortholog); actin filament binding (ortholog); D2 dopamine receptor binding (ortholog); INVOLVED IN actin filament depolymerization (ortholog); actin filament organization (ortholog); calcium-mediated signaling (ortholog); ASSOCIATED WITH Alzheimer's dis ease (ortholog); Cognitive Dysfunction (ortholog); Colorectal Neoplasms (ortholog); FOUND IN actin cytoskeleton (ortholog); cytoplasmic side of dendritic spine plasma membrane (ortholog); dendritic spine (ortholog) | 9 | 26135982 | 26152303 | Dog | 117 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12566736 | Ppp1r9b | protein phosphatase 1 regulatory subunit 9B | ENCODES a protein that exhibits actin binding (ortholog); actin filament binding (ortholog); D2 dopamine receptor binding (ortholog); INVOLVED IN actin filament depolymerization (ortholog); actin filament organization (ortholog); calcium-mediated signaling (ortholog); ASSOCIATED WITH Alzheimer's dis ease (ortholog); Cognitive Dysfunction (ortholog); Colorectal Neoplasms (ortholog); FOUND IN actin cytoskeleton (ortholog); cortical actin cytoskeleton (ortholog); cytoplasmic side of dendritic spine plasma membrane (ortholog) | NW_004936490 | 11497389 | 11514191 | Squirrel | 120 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155244373 | ppp1r9b | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 13865641 | PPP1R9B | protein phosphatase 1 regulatory subunit 9B | ENCODES a protein that exhibits actin binding (ortholog); actin filament binding (ortholog); D2 dopamine receptor binding (ortholog); INVOLVED IN actin filament depolymerization (ortholog); actin filament organization (ortholog); calcium-mediated signaling (ortholog); ASSOCIATED WITH Alzheimer's dis ease (ortholog); Cognitive Dysfunction (ortholog); Colorectal Neoplasms (ortholog); FOUND IN actin cytoskeleton (ortholog); cytoplasmic side of dendritic spine plasma membrane (ortholog); dendritic spine (ortholog) | | | | Pig | 117 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18360896 | PPP1R9B | protein phosphatase 1 regulatory subunit 9B | ENCODES a protein that exhibits actin binding (ortholog); actin filament binding (ortholog); D2 dopamine receptor binding (ortholog); INVOLVED IN actin filament depolymerization (ortholog); actin filament organization (ortholog); calcium-mediated signaling (ortholog); ASSOCIATED WITH Alzheimer's dis ease (ortholog); Cognitive Dysfunction (ortholog); Colorectal Neoplasms (ortholog); FOUND IN actin cytoskeleton (ortholog); cytoplasmic side of dendritic spine plasma membrane (ortholog); dendritic spine (ortholog) | | | | Green Monkey | 118 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626104018 | Ppp1r9b | protein phosphatase 1 regulatory subunit 9B | ENCODES a protein that exhibits actin binding (ortholog); actin filament binding (ortholog); D2 dopamine receptor binding (ortholog); INVOLVED IN actin filament depolymerization (ortholog); actin filament organization (ortholog); calcium-mediated signaling (ortholog); ASSOCIATED WITH Alzheimer's dis ease (ortholog); Cognitive Dysfunction (ortholog); Colorectal Neoplasms (ortholog); FOUND IN actin cytoskeleton (ortholog); cortical actin cytoskeleton (ortholog); cytoplasm (ortholog) | | | | Black Rat | 104 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18931678 | Ppp1r9b | protein phosphatase 1 regulatory subunit 9B | ENCODES a protein that exhibits actin binding (ortholog); actin filament binding (ortholog); D2 dopamine receptor binding (ortholog); INVOLVED IN actin filament depolymerization (ortholog); actin filament organization (ortholog); calcium-mediated signaling (ortholog); ASSOCIATED WITH Alzheimer's dis ease (ortholog); Cognitive Dysfunction (ortholog); Colorectal Neoplasms (ortholog); FOUND IN actin cytoskeleton (ortholog); cortical actin cytoskeleton (ortholog); cytoplasmic side of dendritic spine plasma membrane (ortholog) | | | | Naked Mole-Rat | 120 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155244374 | ppp1r9b.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155236428 | ppp1r9b.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 16556544 | AC002401.1 | novel transcript, antisense to PPP1R9B | | | | | Human | | name | gene, lncrna |