| 632280 | Ppp1r9a | protein phosphatase 1, regulatory subunit 9A | ENCODES a protein that exhibits actin filament binding; GTPase binding; identical protein binding; INVOLVED IN cellular response to toxic substance; excitatory postsynaptic potential; negative regulation of long-term synaptic potentiation; ASSOCIATED WITH hepatocellular carcinoma; Pain; transient ce rebral ischemia; FOUND IN actin cytoskeleton; cytoskeleton; dendrite; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine | 4 | 33936949 | 34258927 | Rat | 206 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1350094 | PPP1R9A | protein phosphatase 1 regulatory subunit 9A | This gene is imprinted, and located in a cluster of imprinted genes on chromosome 7q12. This gene is transcribed in both neuronal and multiple embryonic tissues, and it is maternally expressed mainly in embryonic skeletal muscle tissues and biallelically expressed in other embryonic tissues. The pro tein encoded by this gene includes a PDZ domain and a sterile alpha motif (SAM). It is a regulatory subunit of protein phosphatase I, and controls actin cytoskeleton reorganization. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009] | 7 | 94907236 | 95296415 | Human | 189 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1552999 | Ppp1r9a | protein phosphatase 1, regulatory subunit 9A | Predicted to enable several functions, including actin filament binding activity; enzyme binding activity; and transmembrane transporter binding activity. Involved in modulation of chemical synaptic transmission. Acts upstream of or within actin filament organization and calcium-mediated signaling. Located in cortical actin cytoskeleton; dendritic spine; and filopodium. Is expressed in several structures, including brain; extraembryonic component; genitourinary system; hemolymphoid system gland; and skeletal muscle. Orthologous to human PPP1R9A (protein phosphatase 1 regulatory subunit 9A). [provided by Alliance of Genome Resources, Jul 2025] | 6 | 4902702 | 5165661 | Mouse | 231 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8952810 | Ppp1r9a | protein phosphatase 1 regulatory subunit 9A | ENCODES a protein that exhibits actin filament binding (ortholog); GTPase binding (ortholog); identical protein binding (ortholog); INVOLVED IN actin filament organization (ortholog); calcium-mediated signaling (ortholog); cellular response to toxic substance (ortholog); ASSOCIATED WITH Experimental Seizures (ortholog); hepatocellular carcinoma (ortholog); Huntington's disease (ortholog); FOUND IN actin cytoskeleton (ortholog); cortical actin cytoskeleton (ortholog); cytoskeleton (ortholog) | NW_004955432 | 11607269 | 11891568 | Chinchilla | 64 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11722915 | PPP1R9A | protein phosphatase 1 regulatory subunit 9A | ENCODES a protein that exhibits GTPase binding (ortholog); identical protein binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN actin filament organization (ortholog); calcium-mediated signaling (ortholog); cellular response to toxic substance (ortholog); ASSOCIATED WITH Exp erimental Seizures (ortholog); hepatocellular carcinoma (ortholog); Huntington's disease (ortholog); FOUND IN actin cytoskeleton (ortholog); cortical actin cytoskeleton (ortholog); dendrite (ortholog) | 7 | 86863919 | 87251634 | Bonobo | 77 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12257533 | PPP1R9A | protein phosphatase 1 regulatory subunit 9A | ENCODES a protein that exhibits GTPase binding (ortholog); identical protein binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN actin filament organization (ortholog); calcium-mediated signaling (ortholog); cellular response to toxic substance (ortholog); ASSOCIATED WITH Exp erimental Seizures (ortholog); hepatocellular carcinoma (ortholog); Huntington's disease (ortholog); FOUND IN actin cytoskeleton (ortholog); cortical actin cytoskeleton (ortholog); dendrite (ortholog) | 14 | 20251791 | 20563315 | Dog | 76 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12466561 | Ppp1r9a | protein phosphatase 1 regulatory subunit 9A | ENCODES a protein that exhibits GTPase binding (ortholog); identical protein binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN actin filament organization (ortholog); calcium-mediated signaling (ortholog); cellular response to toxic substance (ortholog); ASSOCIATED WITH Exp erimental Seizures (ortholog); hepatocellular carcinoma (ortholog); Huntington's disease (ortholog); FOUND IN actin cytoskeleton (ortholog); cortical actin cytoskeleton (ortholog); cytoskeleton (ortholog) | NW_004936585 | 4981555 | 5277185 | Squirrel | 71 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14095051 | PPP1R9A | protein phosphatase 1 regulatory subunit 9A | ENCODES a protein that exhibits GTPase binding (ortholog); identical protein binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN actin filament organization (ortholog); calcium-mediated signaling (ortholog); cellular response to toxic substance (ortholog); ASSOCIATED WITH Exp erimental Seizures (ortholog); hepatocellular carcinoma (ortholog); Huntington's disease (ortholog); FOUND IN actin cytoskeleton (ortholog); cortical actin cytoskeleton (ortholog); dendrite (ortholog) | | | | Pig | 76 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18916088 | Ppp1r9a | protein phosphatase 1 regulatory subunit 9A | ENCODES a protein that exhibits GTPase binding (ortholog); identical protein binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN actin filament organization (ortholog); calcium-mediated signaling (ortholog); cellular response to toxic substance (ortholog); ASSOCIATED WITH Exp erimental Seizures (ortholog); hepatocellular carcinoma (ortholog); Huntington's disease (ortholog); FOUND IN actin cytoskeleton (ortholog); cortical actin cytoskeleton (ortholog); dendrite (ortholog) | | | | Naked Mole-Rat | 79 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155236744 | ppp1r9a | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18726131 | PPP1R9A | protein phosphatase 1 regulatory subunit 9A | ENCODES a protein that exhibits GTPase binding (ortholog); identical protein binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN actin filament organization (ortholog); calcium-mediated signaling (ortholog); cellular response to toxic substance (ortholog); ASSOCIATED WITH Exp erimental Seizures (ortholog); hepatocellular carcinoma (ortholog); Huntington's disease (ortholog); FOUND IN actin cytoskeleton (ortholog); cortical actin cytoskeleton (ortholog); dendrite (ortholog) | | | | Green Monkey | 77 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626021336 | Ppp1r9a | protein phosphatase 1 regulatory subunit 9A | ENCODES a protein that exhibits actin filament binding (ortholog); GTPase binding (ortholog); identical protein binding (ortholog); INVOLVED IN actin filament organization (ortholog); calcium-mediated signaling (ortholog); cellular response to toxic substance (ortholog); ASSOCIATED WITH Experimental Seizures (ortholog); hepatocellular carcinoma (ortholog); Huntington's disease (ortholog); FOUND IN actin cytoskeleton (ortholog); cortical actin cytoskeleton (ortholog); cytoskeleton (ortholog) | | | | Black Rat | 64 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155252399 | ppp1r9a.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155236743 | ppp1r9a.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 14984514 | PPP1R9A-AS1 | PPP1R9A antisense RNA 1 | INTERACTS WITH sodium arsenite | 7 | 95035692 | 95214332 | Human | 1 | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 284088835 | ppp1r9al | | | | | | Tropical Clawed Frog | | symbol | gene, null |