PPP1R9A (protein phosphatase 1 regulatory subunit 9A) - Rat Genome Database

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Gene: PPP1R9A (protein phosphatase 1 regulatory subunit 9A) Sus scrofa
Analyze
Symbol: PPP1R9A
Name: protein phosphatase 1 regulatory subunit 9A
RGD ID: 14095051
Description: ENCODES a protein that exhibits GTPase binding (ortholog); identical protein binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN actin filament organization (ortholog); calcium-mediated signaling (ortholog); cellular response to toxic substance (ortholog); ASSOCIATED WITH genetic disease (ortholog); hepatocellular carcinoma (ortholog); Huntington's disease (ortholog); FOUND IN actin cytoskeleton (ortholog); dendrite (ortholog); dendritic spine (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: neurabin-1; protein phosphatase 1, regulatory (inhibitor) subunit 9A
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl974,635,403 - 74,940,362 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1974,635,285 - 74,944,050 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2981,987,561 - 82,105,844 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:21498922   PMID:21675243   PMID:26995566   PMID:30032202  


Genomics

Comparative Map Data
PPP1R9A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl974,635,403 - 74,940,362 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1974,635,285 - 74,944,050 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2981,987,561 - 82,105,844 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PPP1R9A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38794,907,236 - 95,296,415 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl794,907,202 - 95,296,415 (+)EnsemblGRCh38hg38GRCh38
GRCh37794,536,906 - 94,925,727 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36794,374,885 - 94,763,663 (+)NCBINCBI36Build 36hg18NCBI36
Build 34794,185,142 - 94,567,392NCBI
Celera789,235,114 - 89,624,424 (+)NCBICelera
Cytogenetic Map7q21.3NCBI
HuRef789,144,178 - 89,532,759 (+)NCBIHuRef
CHM1_1794,466,972 - 94,855,738 (+)NCBICHM1_1
T2T-CHM13v2.0796,143,048 - 96,532,571 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2793,865,965 - 94,254,723 (+)NCBI
Ppp1r9a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3964,902,702 - 5,165,661 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl64,902,917 - 5,165,661 (+)EnsemblGRCm39 Ensembl
GRCm3864,902,872 - 5,165,661 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl64,902,917 - 5,165,661 (+)EnsemblGRCm38mm10GRCm38
MGSCv3764,853,320 - 5,115,661 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3664,853,320 - 5,115,661 (+)NCBIMGSCv36mm8
Celera65,049,683 - 5,311,917 (+)NCBICelera
Cytogenetic Map6A1NCBI
cM Map61.86NCBI
Ppp1r9a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8433,936,949 - 34,258,927 (+)NCBIGRCr8
mRatBN7.2432,970,501 - 33,292,360 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl433,024,450 - 33,286,907 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx437,980,927 - 38,251,396 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0433,907,063 - 34,177,535 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0432,317,198 - 32,587,313 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0429,976,485 - 30,247,371 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl429,978,739 - 30,241,911 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0429,856,082 - 30,154,334 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4429,654,468 - 29,928,476 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1429,695,157 - 29,966,996 (+)NCBI
Celera428,548,989 - 28,813,836 (+)NCBICelera
Cytogenetic Map4q21NCBI
Ppp1r9a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543211,608,382 - 11,886,044 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543211,607,269 - 11,891,568 (+)NCBIChiLan1.0ChiLan1.0
PPP1R9A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26112,751,561 - 113,136,320 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17161,016,200 - 161,400,959 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0786,863,919 - 87,251,634 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17100,453,090 - 100,839,325 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7100,455,357 - 100,833,220 (+)Ensemblpanpan1.1panPan2
PPP1R9A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11420,251,791 - 20,563,315 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1420,251,738 - 20,557,208 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1419,810,502 - 20,122,327 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01420,073,523 - 20,385,742 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1420,073,561 - 20,383,314 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11420,218,353 - 20,530,386 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01419,953,584 - 20,265,515 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01420,211,007 - 20,522,870 (+)NCBIUU_Cfam_GSD_1.0
Ppp1r9a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511833,585,519 - 33,881,736 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365854,981,555 - 5,277,185 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPP1R9A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12153,744,202 - 54,129,709 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2153,747,857 - 54,127,005 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604250,200,716 - 50,591,491 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ppp1r9a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248131,588,261 - 1,945,788 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248131,587,567 - 1,951,620 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PPP1R9A
4180 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 2 3 23 2
Low 8 4 5 2 2 1 1
Below cutoff 1

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_021063370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021063371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021063372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021063374 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021063375 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021063376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021063377 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021063378 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021063379 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021063380 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021063381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021063382 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021063383 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021063384 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AEMK02000070 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK349398 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF619476 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSSCT00000016702   ⟹   ENSSSCP00000016256
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl974,636,174 - 74,940,362 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000037238   ⟹   ENSSSCP00000050591
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl974,636,174 - 74,940,362 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000053487   ⟹   ENSSSCP00000032024
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl974,636,174 - 74,939,075 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000058476   ⟹   ENSSSCP00000040730
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl974,636,174 - 74,940,362 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000065331   ⟹   ENSSSCP00000031704
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl974,635,403 - 74,938,758 (+)Ensembl
RefSeq Acc Id: XM_021063370   ⟹   XP_020919029
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1974,635,285 - 74,944,050 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021063371   ⟹   XP_020919030
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1974,635,796 - 74,944,050 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021063372   ⟹   XP_020919031
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1974,636,002 - 74,944,050 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021063374   ⟹   XP_020919033
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1974,635,285 - 74,944,050 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021063375   ⟹   XP_020919034
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1974,635,285 - 74,944,050 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021063376   ⟹   XP_020919035
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1974,635,285 - 74,944,050 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021063377   ⟹   XP_020919036
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1974,635,729 - 74,944,050 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021063378   ⟹   XP_020919037
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1974,636,003 - 74,944,050 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021063379   ⟹   XP_020919038
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1974,635,285 - 74,944,050 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021063380   ⟹   XP_020919039
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1974,635,285 - 74,944,050 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021063381   ⟹   XP_020919040
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1974,635,285 - 74,944,050 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021063382   ⟹   XP_020919041
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1974,635,285 - 74,944,050 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021063383   ⟹   XP_020919042
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1974,635,285 - 74,944,050 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021063384   ⟹   XP_020919043
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1974,635,285 - 74,944,050 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020919029   ⟸   XM_021063370
- Peptide Label: isoform X1
- UniProtKB: A0A8D1LXS1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020919038   ⟸   XM_021063379
- Peptide Label: isoform X5
- UniProtKB: A0A8D1LXS6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020919033   ⟸   XM_021063374
- Peptide Label: isoform X2
- UniProtKB: A0A8D1LXS1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020919039   ⟸   XM_021063380
- Peptide Label: isoform X6
- UniProtKB: A0A287A9Q2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020919040   ⟸   XM_021063381
- Peptide Label: isoform X7
- UniProtKB: A0A287A9Q2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020919034   ⟸   XM_021063375
- Peptide Label: isoform X3
- UniProtKB: A0A287B2F8 (UniProtKB/TrEMBL),   A0A4X1TS24 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020919035   ⟸   XM_021063376
- Peptide Label: isoform X4
- UniProtKB: F1SFA4 (UniProtKB/TrEMBL),   A0A4X1TWW2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020919043   ⟸   XM_021063384
- Peptide Label: isoform X10
- UniProtKB: A0A4X1TWW2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020919041   ⟸   XM_021063382
- Peptide Label: isoform X8
- UniProtKB: A0A286ZJP9 (UniProtKB/TrEMBL),   A0A4X1TX20 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020919042   ⟸   XM_021063383
- Peptide Label: isoform X9
- UniProtKB: A0A4X1TX20 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020919036   ⟸   XM_021063377
- Peptide Label: isoform X4
- UniProtKB: F1SFA4 (UniProtKB/TrEMBL),   A0A4X1TWW2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020919030   ⟸   XM_021063371
- Peptide Label: isoform X1
- UniProtKB: A0A8D1LXS1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020919031   ⟸   XM_021063372
- Peptide Label: isoform X1
- UniProtKB: A0A8D1LXS1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020919037   ⟸   XM_021063378
- Peptide Label: isoform X4
- UniProtKB: F1SFA4 (UniProtKB/TrEMBL),   A0A4X1TWW2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000040730   ⟸   ENSSSCT00000058476
RefSeq Acc Id: ENSSSCP00000031704   ⟸   ENSSSCT00000065331
RefSeq Acc Id: ENSSSCP00000016256   ⟸   ENSSSCT00000016702
RefSeq Acc Id: ENSSSCP00000050591   ⟸   ENSSSCT00000037238
RefSeq Acc Id: ENSSSCP00000032024   ⟸   ENSSSCT00000053487
Protein Domains
PDZ   SAM


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000015329 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00050026270 UniProtKB/TrEMBL
  ENSSSCG00070012223 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000016702 ENTREZGENE
  ENSSSCT00000016702.5 UniProtKB/TrEMBL
  ENSSSCT00000037238 ENTREZGENE
  ENSSSCT00000037238.3 UniProtKB/TrEMBL
  ENSSSCT00000053487 ENTREZGENE
  ENSSSCT00000053487.3 UniProtKB/TrEMBL
  ENSSSCT00000058476 ENTREZGENE
  ENSSSCT00000058476.3 UniProtKB/TrEMBL
  ENSSSCT00000065331 ENTREZGENE
  ENSSSCT00000065331.3 UniProtKB/TrEMBL
  ENSSSCT00050035352.1 UniProtKB/TrEMBL
  ENSSSCT00050035401.1 UniProtKB/TrEMBL
  ENSSSCT00050035434.1 UniProtKB/TrEMBL
  ENSSSCT00070024123.1 UniProtKB/TrEMBL
  ENSSSCT00070024148.1 UniProtKB/TrEMBL
  ENSSSCT00070024154.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.150.50 UniProtKB/TrEMBL
  2.30.42.10 UniProtKB/TrEMBL
InterPro Neurabin-1/2_PDZ UniProtKB/TrEMBL
  Neurabin-like UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
  PDZ_sf UniProtKB/TrEMBL
  SAM UniProtKB/TrEMBL
  SAM/pointed_sf UniProtKB/TrEMBL
NCBI Gene PPP1R9A ENTREZGENE
PANTHER PTHR16154 UniProtKB/TrEMBL
  PTHR16154:SF22 UniProtKB/TrEMBL
Pfam PDZ UniProtKB/TrEMBL
  PDZ_5 UniProtKB/TrEMBL
  SAM_2 UniProtKB/TrEMBL
PROSITE PDZ UniProtKB/TrEMBL
  SAM_DOMAIN UniProtKB/TrEMBL
SMART PDZ UniProtKB/TrEMBL
  SAM UniProtKB/TrEMBL
Superfamily-SCOP SSF47769 UniProtKB/TrEMBL
  SSF50156 UniProtKB/TrEMBL
UniProt A0A286ZJP9 ENTREZGENE, UniProtKB/TrEMBL
  A0A286ZKM9_PIG UniProtKB/TrEMBL
  A0A287A9Q2 ENTREZGENE, UniProtKB/TrEMBL
  A0A287B2F8 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1TS24 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1TWW2 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1TX20 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1LXS1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1LXS6 ENTREZGENE, UniProtKB/TrEMBL
  F1SFA4 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:91743 ENTREZGENE