| 621878 | Podxl | podocalyxin-like | INVOLVED IN negative regulation of cell adhesion; podocyte development; cell migration (ortholog); ASSOCIATED WITH carotid artery disease (ortholog); early-onset Parkinson's disease (ortholog); genetic disease (ortholog); FOUND IN apical plasma membrane; cell body; slit diaphragm; INTERACTS WITH 17a lpha-ethynylestradiol; 17beta-estradiol; 2,2,2-tetramine | 4 | 61102434 | 61149131 | Rat | 253 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 736843 | PODXL | podocalyxin like | This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin. [provided by RefSeq, Jul 2008] | 7 | 131500271 | 131556628 | Human | 302 | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 736844 | Podxl | podocalyxin-like | Involved in several processes, including negative regulation of cell-cell adhesion; regulation of microvillus assembly; and regulation of synapse assembly. Acts upstream of or within leukocyte migration. Located in apical plasma membrane and microvillus membrane. Is active in glutamatergic synapse a nd presynaptic membrane. Is expressed in several structures, including genitourinary system; integumental system; intraembryonic coelom; nervous system; and sensory organ. Orthologous to human PODXL (podocalyxin like). [provided by Alliance of Genome Resources, Jul 2025] | 6 | 31496428 | 31540872 | Mouse | 279 | symbol , PhenoGen , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 8917398 | Podxl | podocalyxin like | INVOLVED IN cell migration (ortholog); epithelial tube formation (ortholog); leukocyte migration (ortholog); ASSOCIATED WITH carotid artery disease (ortholog); early-onset Parkinson's disease (ortholog); genetic disease (ortholog); FOUND IN apical plasma membrane (ortholog); cell body (ortholog); cy toplasm (ortholog) | NW_004955410 | 36191797 | 36239970 | Chinchilla | 44 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11978478 | PODXL | podocalyxin like | INVOLVED IN epithelial tube formation (ortholog); leukocyte migration (ortholog); negative regulation of cell adhesion (ortholog); ASSOCIATED WITH carotid artery disease (ortholog); early-onset Parkinson's disease (ortholog); genetic disease (ortholog); FOUND IN apical plasma membrane (ortholog); ce ll body (ortholog); glutamatergic synapse (ortholog) | 7 | 123467140 | 123523503 | Bonobo | 56 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12127430 | PODXL | podocalyxin like | INVOLVED IN epithelial tube formation; cell migration (ortholog); leukocyte migration (ortholog); ASSOCIATED WITH carotid artery disease (ortholog); early-onset Parkinson's disease (ortholog); genetic disease (ortholog); FOUND IN apical plasma membrane; cell body (ortholog); cytoplasm (ortholog) | 14 | 5614006 | 5625360 | Dog | 62 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 12637177 | Podxl | podocalyxin like | INVOLVED IN epithelial tube formation (ortholog); leukocyte migration (ortholog); negative regulation of cell adhesion (ortholog); ASSOCIATED WITH carotid artery disease (ortholog); early-onset Parkinson's disease (ortholog); genetic disease (ortholog); FOUND IN apical plasma membrane (ortholog); ce ll body (ortholog); cytoplasm (ortholog) | NW_004936579 | 3960338 | 3970925 | Squirrel | 51 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14204057 | PODXL | podocalyxin like | INVOLVED IN epithelial tube formation (ortholog); leukocyte migration (ortholog); negative regulation of cell adhesion (ortholog); ASSOCIATED WITH carotid artery disease (ortholog); early-onset Parkinson's disease (ortholog); genetic disease (ortholog); FOUND IN apical plasma membrane (ortholog); ce ll body (ortholog); cytoplasm (ortholog) | | | | Pig | 52 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18582214 | PODXL | podocalyxin like | INVOLVED IN epithelial tube formation (ortholog); leukocyte migration (ortholog); negative regulation of cell adhesion (ortholog); ASSOCIATED WITH carotid artery disease (ortholog); early-onset Parkinson's disease (ortholog); genetic disease (ortholog); FOUND IN apical plasma membrane (ortholog); ce ll body (ortholog); glutamatergic synapse (ortholog) | | | | Green Monkey | 56 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 284888186 | podxl | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18930032 | Podxl | podocalyxin like | INVOLVED IN epithelial tube formation (ortholog); leukocyte migration (ortholog); negative regulation of cell adhesion (ortholog); ASSOCIATED WITH carotid artery disease (ortholog); early-onset Parkinson's disease (ortholog); genetic disease (ortholog); FOUND IN apical plasma membrane (ortholog); ce ll body (ortholog); cytoplasm (ortholog) | | | | Naked Mole-Rat | 51 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625950234 | Podxl | podocalyxin like | INVOLVED IN cell migration (ortholog); epithelial tube formation (ortholog); leukocyte migration (ortholog); ASSOCIATED WITH carotid artery disease (ortholog); early-onset Parkinson's disease (ortholog); genetic disease (ortholog); FOUND IN apical plasma membrane (ortholog); cell body (ortholog); cy toplasm (ortholog) | | | | Black Rat | 44 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626469187 | podxl.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 626180583 | podxl.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 1642176 | Podxlm1Mcwi | podocalyxin-like; mutation 1, Medical College of Wisconsin | mutation generated by ENU (N-ethyl-N-nitrourea); T154A mutation is generated from the codon change ACA/GCA | | | | Rat | | symbol , old_gene_symbol | gene, allele |
| 1305815 | Podxl2 | podocalyxin-like 2 | INVOLVED IN leukocyte tethering or rolling (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 4 | 122863476 | 122895318 | Rat | 65 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1347781 | PODXL2 | podocalyxin like 2 | This gene is a member of the CD34 family of cell surface transmembrane proteins, which are characterized by an N-terminal extracellular mucin domain, globular and stalk domains, a single pass transmembrane region, and a charged cytoplasmic tail. The encoded protein is a ligand for vascular selectins . [provided by RefSeq, Oct 2012] | 3 | 127629185 | 127672802 | Human | 67 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1552380 | Podxl2 | podocalyxin-like 2 | Predicted to be involved in leukocyte tethering or rolling. Predicted to be located in plasma membrane. Is expressed in genitourinary system; gut; nervous system; respiratory tract; and sensory organ. Orthologous to human PODXL2 (podocalyxin like 2). [provided b y Alliance of Genome Resources, Jul 2025] | 6 | 88819539 | 88852063 | Mouse | 71 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8931334 | Podxl2 | podocalyxin like 2 | INVOLVED IN leukocyte tethering or rolling (ortholog) | NW_004955429 | 15968877 | 15995617 | Chinchilla | 3 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11981324 | PODXL2 | podocalyxin like 2 | INVOLVED IN cell adhesion (inferred); leukocyte tethering or rolling (inferred); FOUND IN membrane (inferred); plasma membrane (inferred) | 3 | 124673860 | 124717469 | Bonobo | 7 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12128582 | PODXL2 | podocalyxin like 2 | INVOLVED IN cell adhesion (inferred); leukocyte tethering or rolling (inferred); FOUND IN membrane (inferred); plasma membrane (inferred) | 20 | 1716672 | 1752872 | Dog | 7 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12523332 | Podxl2 | podocalyxin like 2 | INVOLVED IN leukocyte tethering or rolling (ortholog) | NW_004936798 | 736003 | 745634 | Squirrel | 3 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 284156382 | podxl2 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 14093023 | PODXL2 | podocalyxin like 2 | INVOLVED IN cell adhesion (inferred); leukocyte tethering or rolling (inferred); FOUND IN membrane (inferred); plasma membrane (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 8 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18777407 | PODXL2 | podocalyxin like 2 | INVOLVED IN cell adhesion (inferred); leukocyte tethering or rolling (inferred); FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Green Monkey | 7 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18929574 | Podxl2 | podocalyxin like 2 | INVOLVED IN cell adhesion (inferred); leukocyte tethering or rolling (inferred); FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Naked Mole-Rat | 6 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625892810 | Podxl2 | podocalyxin like 2 | INVOLVED IN leukocyte tethering or rolling (ortholog) | | | | Black Rat | 3 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 284155482 | podxl2.S | | | | | | African Clawed Frog | | symbol | gene, null |