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15 records found for search term Pde5a
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
620995Pde5aphosphodiesterase 5AENCODES a protein that exhibits 3',5'-cyclic-GMP phosphodiesterase activity; 3',5'-cyclic-nucleotide phosphodiesterase activity (ortholog); cGMP binding (ortholog); INVOLVED IN nervous system development; positive regulation of apoptotic process; positive regulation of chronic inflammatory response;2213542822213687638Rat241symbol , PhenoGen , old_gene_symbolgene, protein-coding, PROVISIONAL [RefSeq]
732674PDE5Aphosphodiesterase 5AThis gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for sm4119494403119628804Human245symbol , old_gene_name , COSMIC , Human Proteome Map , old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
737352Pde5aphosphodiesterase 5A, cGMP-specificEnables 3',5'-cyclic-nucleotide phosphodiesterase activity and cGMP binding activity. Involved in positive regulation of MAP kinase activity; regulation of muscle system process; and relaxation of cardiac muscle. Acts upstream of or within several processes, including cGMP catabolic process; positiv3122522822122653023Mouse253symbol , PhenoGen , description , old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
9016314Pde5aphosphodiesterase 5AENCODES a protein that exhibits 3',5'-cyclic-GMP phosphodiesterase activity (ortholog); 3',5'-cyclic-nucleotide phosphodiesterase activity (ortholog); cGMP binding (ortholog); INVOLVED IN cGMP catabolic process (ortholog); cGMP metabolic process (ortholog); negative regulation of cardiac muscle contNW_0049554282078549720904717Chinchilla48symbolgene, protein-coding, MODEL [RefSeq]
11972644PDE5Aphosphodiesterase 5AENCODES a protein that exhibits 3',5'-cyclic-GMP phosphodiesterase activity (ortholog); cyclic-nucleotide phosphodiesterase activity (ortholog); INVOLVED IN cGMP catabolic process (ortholog); cGMP metabolic process (ortholog); negative regulation of cardiac muscle contraction (ortholog); ASSOCIATED 4111682772111817234Bonobo58symbolgene, protein-coding, MODEL [RefSeq]
12214293PDE5Aphosphodiesterase 5AENCODES a protein that exhibits 3',5'-cyclic-GMP phosphodiesterase activity (ortholog); cyclic-nucleotide phosphodiesterase activity (ortholog); INVOLVED IN cGMP catabolic process (ortholog); cGMP metabolic process (ortholog); negative regulation of cardiac muscle contraction (ortholog); ASSOCIATED 323827257338407517Dog65symbolgene, protein-coding, PROVISIONAL [RefSeq]
12554341Pde5aphosphodiesterase 5AENCODES a protein that exhibits 3',5'-cyclic-GMP phosphodiesterase activity (ortholog); cyclic-nucleotide phosphodiesterase activity (ortholog); INVOLVED IN cGMP catabolic process (ortholog); cGMP metabolic process (ortholog); negative regulation of cardiac muscle contraction (ortholog); ASSOCIATED NW_00493686924265117120Squirrel58symbolgene, protein-coding, MODEL [RefSeq]
14012509PDE5Aphosphodiesterase 5AENCODES a protein that exhibits 3',5'-cyclic-GMP phosphodiesterase activity (ortholog); cyclic-nucleotide phosphodiesterase activity (ortholog); INVOLVED IN cGMP catabolic process (ortholog); cGMP metabolic process (ortholog); negative regulation of cardiac muscle contraction (ortholog); ASSOCIATED Pig61symbolgene, protein-coding, MODEL [RefSeq]
18924056Pde5aphosphodiesterase 5AENCODES a protein that exhibits 3',5'-cyclic-GMP phosphodiesterase activity (ortholog); cGMP binding (ortholog); cyclic-nucleotide phosphodiesterase activity (ortholog); INVOLVED IN cGMP catabolic process (ortholog); cGMP metabolic process (ortholog); negative regulation of cardiac muscle contractioNaked Mole-Rat53symbolgene, protein-coding, MODEL [RefSeq]
625965350Pde5aphosphodiesterase 5AENCODES a protein that exhibits 3',5'-cyclic-GMP phosphodiesterase activity (ortholog); 3',5'-cyclic-nucleotide phosphodiesterase activity (ortholog); cGMP binding (ortholog); INVOLVED IN cGMP catabolic process (ortholog); cGMP metabolic process (ortholog); negative regulation of cardiac muscle contBlack Rat48symbolgene, protein-coding, MODEL [RefSeq]
18496827PDE5Aphosphodiesterase 5AENCODES a protein that exhibits 3',5'-cyclic-GMP phosphodiesterase activity (ortholog); cyclic-nucleotide phosphodiesterase activity (ortholog); INVOLVED IN cGMP catabolic process (ortholog); cGMP metabolic process (ortholog); negative regulation of cardiac muscle contraction (ortholog); ASSOCIATED Green Monkey58symbolgene, protein-coding, MODEL [RefSeq]
155237866pde5aTropical Clawed Frogsymbolgene, null
155247327pde5a.LAfrican Clawed Frogsymbolgene, null
155241755pde5a.SAfrican Clawed Frogsymbolgene, null
2290151Pde5aTn(sb-T2/Bart3)2.144Mcwiphosphodiesterase 5A, cGMP-specific; transposon insertion 2.144, Medical College of Wisconsintrap construct into the 4th intron of the Pde5a geneRatsymbol , description , old_gene_symbolgene, allele