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Gene: PDE5A (phosphodiesterase 5A) Sus scrofa
Analyze
Symbol: PDE5A
Name: phosphodiesterase 5A
Description: ENCODES a protein that exhibits 3',5'-cyclic-nucleotide phosphodiesterase activity (inferred); cGMP binding (inferred); metal ion binding (inferred); INVOLVED IN cGMP catabolic process (inferred); negative regulation of cardiac muscle contraction (inferred); negative regulation of T cell proliferation (inferred); PARTICIPATES IN purine metabolic pathway; ASSOCIATED WITH Cardiomegaly (ortholog); Diabetes Mellitus, Experimental (ortholog); Hearing Loss (ortholog); INTERACTS WITH 3',5'-cyclic GMP
Type: protein-coding
RefSeq Status: MODEL
Also known as: cGMP-dependent 3',5'-cyclic phosphodiesterase 5A; cGMP-specific 3',5'-cyclic phosphodiesterase; PDE5; phosphodiesterase isozyme 5
Orthologs:
Homo sapiens (human) : PDE5A (phosphodiesterase 5A)  HGNC  Alliance
Mus musculus (house mouse) : Pde5a (phosphodiesterase 5A, cGMP-specific)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pde5a (phosphodiesterase 5A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pde5a (phosphodiesterase 5A)
Pan paniscus (bonobo/pygmy chimpanzee) : PDE5A (phosphodiesterase 5A)
Canis lupus familiaris (dog) : PDE5A (phosphodiesterase 5A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pde5a (phosphodiesterase 5A)
Chlorocebus sabaeus (green monkey) : PDE5A (phosphodiesterase 5A)
Heterocephalus glaber (naked mole-rat) : Pde5a (phosphodiesterase 5A)
more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8104,270,881 - 104,420,947 (+)Ensembl
Sscrofa11.18104,270,858 - 104,420,955 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28111,948,578 - 112,077,533 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
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References - uncurated

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Expression


Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
  
More on PDE5A
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 14012509
Created: 2019-01-29
Species: Sus scrofa
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.