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Gene: PDE5A (phosphodiesterase 5A) Sus scrofa
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Symbol: PDE5A
Name: phosphodiesterase 5A
Description: ENCODES a protein that exhibits 3',5'-cyclic-nucleotide phosphodiesterase activity (inferred); cGMP binding (inferred); metal ion binding (inferred); INVOLVED IN cGMP catabolic process (inferred); negative regulation of cardiac muscle contraction (inferred); negative regulation of T cell proliferation (inferred); PARTICIPATES IN purine metabolic pathway; ASSOCIATED WITH Cardiomegaly (ortholog); Diabetes Mellitus, Experimental (ortholog); Hearing Loss (ortholog); INTERACTS WITH 3',5'-cyclic GMP
Type: protein-coding
RefSeq Status: MODEL
Also known as: cGMP-dependent 3',5'-cyclic phosphodiesterase 5A; cGMP-specific 3',5'-cyclic phosphodiesterase; PDE5; phosphodiesterase isozyme 5
Orthologs:
Homo sapiens (human) : PDE5A (phosphodiesterase 5A)  HGNC  Alliance
Mus musculus (house mouse) : Pde5a (phosphodiesterase 5A, cGMP-specific)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pde5a (phosphodiesterase 5A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pde5a (phosphodiesterase 5A)
Pan paniscus (bonobo/pygmy chimpanzee) : PDE5A (phosphodiesterase 5A)
Canis lupus familiaris (dog) : PDE5A (phosphodiesterase 5A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pde5a (phosphodiesterase 5A)
Chlorocebus sabaeus (green monkey) : PDE5A (phosphodiesterase 5A)
Heterocephalus glaber (naked mole-rat) : Pde5a (phosphodiesterase 5A)
more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8104,270,881 - 104,420,947 (+)Ensembl
Sscrofa11.18104,270,858 - 104,420,955 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28111,948,578 - 112,077,533 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - uncurated

Genomics

Comparative Map Data

Expression


Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
 
More on PDE5A
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 14012509
Created: 2019-01-29
Species: Sus scrofa
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.