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18 records found for search term Pde3a
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
61942Pde3aphosphodiesterase 3AENCODES a protein that exhibits 3',5'-cGMP-inhibited cyclic-nucleotide phosphodiesterase activity (ortholog); 3',5'-cyclic-AMP phosphodiesterase activity (ortholog); 3',5'-cyclic-GMP phosphodiesterase activity (ortholog); INVOLVED IN negative regulation of apoptotic process; negative regulation of c4175904276176170531Rat204symbol , PhenoGen , old_gene_symbolgene, protein-coding, PROVISIONAL [RefSeq]
62235Pde3aphosphodiesterase 3A, cGMP inhibitedEnables 3',5'-cyclic-AMP phosphodiesterase activity. Acts upstream of or within several processes, including oocyte maturation; positive regulation of oocyte development; and regulation of meiotic nuclear division. Located in cytosol and membrane. Is expressed in several structures, including alimen6141194995141452588Mouse208symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
734436PDE3Aphosphodiesterase 3AThis gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded pro122036853720688583Human267symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
8793209Pde3aphosphodiesterase 3AENCODES a protein that exhibits 3',5'-cGMP-inhibited cyclic-nucleotide phosphodiesterase activity (ortholog); 3',5'-cyclic-AMP phosphodiesterase activity (ortholog); 3',5'-cyclic-GMP phosphodiesterase activity (ortholog); INVOLVED IN apoptotic signaling pathway (ortholog); cellular response to cGMP NW_0049554131634082716642731Chinchilla41symbolgene, protein-coding, MODEL [RefSeq]
11724973PDE3Aphosphodiesterase 3AENCODES a protein that exhibits 3',5'-cGMP-inhibited cyclic-nucleotide phosphodiesterase activity (inferred); 3',5'-cyclic-AMP phosphodiesterase activity (inferred); 3',5'-cyclic-GMP phosphodiesterase activity (inferred); INVOLVED IN negative regulation of apoptotic process (ortholog); negative regu122038021320690540Bonobo52symbolgene, protein-coding, MODEL [RefSeq]
12386423PDE3Aphosphodiesterase 3AENCODES a protein that exhibits 3',5'-cGMP-inhibited cyclic-nucleotide phosphodiesterase activity (inferred); 3',5'-cyclic-AMP phosphodiesterase activity (inferred); 3',5'-cyclic-GMP phosphodiesterase activity (inferred); INVOLVED IN negative regulation of apoptotic process (ortholog); negative regu272655555826878624Dog52symbolgene, protein-coding, MODEL [RefSeq]
12615142Pde3aphosphodiesterase 3AENCODES a protein that exhibits 3',5'-cGMP-inhibited cyclic-nucleotide phosphodiesterase activity (inferred); 3',5'-cyclic-AMP phosphodiesterase activity (inferred); 3',5'-cyclic-GMP phosphodiesterase activity (inferred); INVOLVED IN negative regulation of apoptotic process (ortholog); negative reguNW_00493654857586346072195Squirrel51symbolgene, protein-coding, MODEL [RefSeq]
18924213Pde3aphosphodiesterase 3AENCODES a protein that exhibits 3',5'-cGMP-inhibited cyclic-nucleotide phosphodiesterase activity (ortholog); estrogen binding (ortholog); nuclear estrogen receptor activity (ortholog); INVOLVED IN apoptotic signaling pathway (ortholog); cellular response to cGMP (ortholog); cellular response to traNaked Mole-Rat47symbolgene, protein-coding, MODEL [RefSeq]
626468809pde3aTropical Clawed Frogsymbolgene, null
626468743pde3aTropical Clawed Frogsymbolgene, null
18601642PDE3Aphosphodiesterase 3AENCODES a protein that exhibits 3',5'-cGMP-inhibited cyclic-nucleotide phosphodiesterase activity (inferred); 3',5'-cyclic-AMP phosphodiesterase activity (inferred); 3',5'-cyclic-GMP phosphodiesterase activity (inferred); INVOLVED IN negative regulation of apoptotic process (ortholog); negative reguGreen Monkey52symbolgene, protein-coding, MODEL [RefSeq]
625849829Pde3aphosphodiesterase 3AENCODES a protein that exhibits 3',5'-cGMP-inhibited cyclic-nucleotide phosphodiesterase activity (ortholog); 3',5'-cyclic-AMP phosphodiesterase activity (ortholog); 3',5'-cyclic-GMP phosphodiesterase activity (ortholog); INVOLVED IN apoptotic signaling pathway (ortholog); cellular response to cGMP Black Rat41symbolgene, protein-coding, MODEL [RefSeq]
14128362PDE3Aphosphodiesterase 3AENCODES a protein that exhibits 3',5'-cGMP-inhibited cyclic-nucleotide phosphodiesterase activity (ortholog); 3',5'-cyclic-AMP phosphodiesterase activity (ortholog); cAMP binding (ortholog); INVOLVED IN negative regulation of apoptotic process (ortholog); negative regulation of cAMP/PKA signal transPig63symbolgene, protein-coding, PROVISIONAL [RefSeq]
626468975pde3aTropical Clawed Frogsymbolgene, null
124713593PDE3A-AS1PDE3A antisense RNA 1122035917520370256Humansymbol , COSMIC , name , Human Proteome Mapgene, ncrna, VALIDATED [RefSeq]
155631294Pde3aem1Bdrphosphodiesterase 3A; Cas9/Cas9 induced mutant 1, BdrThe rat mutant allele was generated by pronuclear microinjection of Sprague-Dawley rat zygotes with a mixture of Cas9/Cas9 system to target the region in the rat Pde3a gene homologous to the human T445N mutation. The rat model exhibits a 9-bp deletion within theRatsymbol , descriptiongene, allele
155631296Pde3aem2Bdrphosphodiesterase 3A; Cas9/Cas9 induced mutant 2, BdrThe rat mutant allele was generated by pronuclear microinjection of Sprague-Dawley rat zygotes with a mixture of Cas9/Cas9 system to target the region in the rat Pde3a gene homologous to the human T445N mutation. The rat model exhibits a 20-bp deletion within thRatsymbol , descriptiongene, allele
155631299Pde3aem3Bdrphosphodiesterase 3A; Cas9/Cas9 induced mutant 3, BdrThe rat mutant allele was generated by pronuclear microinjection of Sprague-Dawley rat zygotes with a mixture of Cas9/Cas9 system to target the catalytic domain in the rat Pde3a gene. The model has a carriesa CGT to TGT missense mutation and results in R862C subRatsymbol , descriptiongene, allele