Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Pde3a (phosphodiesterase 3A, cGMP inhibited) Mus musculus
Analyze
Symbol: Pde3a
Name: phosphodiesterase 3A, cGMP inhibited
RGD ID: 62235
Description: Exhibits 3',5'-cyclic-AMP phosphodiesterase activity. Involved in several processes, including oocyte maturation; positive regulation of oocyte development; and regulation of meiotic nuclear division. Localizes to cytosol and membrane. Is expressed in several structures, including alimentary system; central nervous system; cranium; genitourinary system; and integumental system. Human ortholog(s) of this gene implicated in hypertension and brachydactyly syndrome. Orthologous to human PDE3A (phosphodiesterase 3A); PARTICIPATES IN protein kinase A (PKA) signaling pathway; insulin signaling pathway; purine metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A930022O17Rik; C87899; CGI-PDE A; cGMP-inhibited 3',5'-cyclic phosphodiesterase A; cGMP-inhibited phosphodiesterase; cyclic GMP-inhibited phosphodiesterase A
Orthologs:
Homo sapiens (human) : PDE3A (phosphodiesterase 3A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pde3a (phosphodiesterase 3A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pde3a (phosphodiesterase 3A)
Pan paniscus (bonobo/pygmy chimpanzee) : PDE3A (phosphodiesterase 3A)
Canis lupus familiaris (dog) : PDE3A (phosphodiesterase 3A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pde3a (phosphodiesterase 3A)
Sus scrofa (pig) : PDE3A (phosphodiesterase 3A)
Chlorocebus sabaeus (African green monkey) : PDE3A (phosphodiesterase 3A)
Heterocephalus glaber (naked mole-rat) : Pde3a (phosphodiesterase 3A)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl6141,249,269 - 141,507,448 (+)EnsemblGRCm38mm10GRCm38
GRCm386141,249,269 - 141,506,862 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv376141,197,790 - 141,447,872 (+)NCBIGRCm37mm9NCBIm37
MGSCv366141,211,675 - 141,461,757 (+)NCBImm8
Celera6144,313,875 - 144,561,276 (+)NCBICelera
Cytogenetic Map6G2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Pde3a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 62235
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2020-08-18
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.