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Gene: Pde3a (phosphodiesterase 3A, cGMP inhibited) Mus musculus
Symbol: Pde3a
Name: phosphodiesterase 3A, cGMP inhibited
RGD ID: 62235
Description: Exhibits 3',5'-cyclic-AMP phosphodiesterase activity. Involved in several processes, including oocyte maturation; positive regulation of oocyte development; and regulation of meiotic nuclear division. Localizes to cytosol and membrane. Is expressed in several structures, including alimentary system; central nervous system; cranium; genitourinary system; and integumental system. Human ortholog(s) of this gene implicated in hypertension and brachydactyly syndrome. Orthologous to human PDE3A (phosphodiesterase 3A); PARTICIPATES IN protein kinase A (PKA) signaling pathway; insulin signaling pathway; purine metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A930022O17Rik; C87899; CGI-PDE A; cGMP-inhibited 3',5'-cyclic phosphodiesterase A; cGMP-inhibited phosphodiesterase; cyclic GMP-inhibited phosphodiesterase A
Homo sapiens (human) : PDE3A (phosphodiesterase 3A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pde3a (phosphodiesterase 3A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pde3a (phosphodiesterase 3A)
Pan paniscus (bonobo/pygmy chimpanzee) : PDE3A (phosphodiesterase 3A)
Canis lupus familiaris (dog) : PDE3A (phosphodiesterase 3A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pde3a (phosphodiesterase 3A)
Sus scrofa (pig) : PDE3A (phosphodiesterase 3A)
Chlorocebus sabaeus (African green monkey) : PDE3A (phosphodiesterase 3A)
Heterocephalus glaber (naked mole-rat) : Pde3a (phosphodiesterase 3A)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl6141,249,269 - 141,507,448 (+)EnsemblGRCm38mm10GRCm38
GRCm386141,249,269 - 141,506,862 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv376141,197,790 - 141,447,872 (+)NCBIGRCm37mm9NCBIm37
MGSCv366141,211,675 - 141,461,757 (+)NCBImm8
Celera6144,313,875 - 144,561,276 (+)NCBICelera
Cytogenetic Map6G2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Pde3a
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 62235
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2020-08-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.