| 1311270 | Nvl | nuclear VCP-like | ENCODES a protein that exhibits ATP binding (ortholog); preribosome binding (ortholog); INVOLVED IN positive regulation of telomere maintenance (ortholog); regulation of protein localization to nucleolus (ortholog); ribosomal large subunit biogenesis (ortholog); PARTICIPATES IN ribosome biogenesis p athway; FOUND IN nuclear exosome (RNase complex) (ortholog); nucleolus (ortholog); nucleoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 13 | 95385389 | 95438490 | Rat | 69 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1322636 | NVL | nuclear VCP like | This gene encodes a member of the AAA (ATPases associated with diverse cellular activities) superfamily. Multiple transcript variants encoding different isoforms have been found for this gene. Two encoded proteins, described as major and minor isoforms, have been localized to distinct regions of the nucleus. The largest encoded protein (major isoform) has been localized to the nucleolus and shown to participate in ribosome biosynthesis (PMID: 15469983, 16782053), while the minor isoform has been localized to the nucleoplasmin. [provided by RefSeq, Aug 2011] | 1 | 224227345 | 224330172 | Human | 82 | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1322637 | Nvl | nuclear VCP-like | Predicted to enable ATP binding activity; ATP hydrolysis activity; and preribosome binding activity. Predicted to be involved in rRNA processing; regulation of protein localization to nucleolus; and ribosomal large subunit biogenesis. Predicted to be located in nucleoplasm. Predicted to be part of n uclear exosome (RNase complex) and telomerase holoenzyme complex. Predicted to be active in nucleus. Predicted to colocalize with nucleolus. Orthologous to human NVL (nuclear VCP like). [provided by Alliance of Genome Resources, Apr 2025] | 1 | 180914703 | 180974557 | Mouse | 101 | symbol , PhenoGen , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 8980889 | Nvl | nuclear VCP like | ENCODES a protein that exhibits ATP binding (ortholog); preribosome binding (ortholog); INVOLVED IN positive regulation of telomere maintenance (ortholog); regulation of protein localization to nucleolus (ortholog); ribosomal large subunit biogenesis (ortholog); FOUND IN nuclear exosome (RNase compl ex) (ortholog); nucleolus (ortholog); nucleoplasm (ortholog) | NW_004955520 | 1010966 | 1069176 | Chinchilla | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11703801 | NVL | nuclear VCP like | ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); nucleotide binding (inferred); INVOLVED IN positive regulation of telomere maintenance (ortholog); FOUND IN nuclear exosome (RNase complex) (inferred); nucleolus (inferred); nucleoplasm (inferred) | 1 | 199695388 | 199798080 | Bonobo | 32 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12240844 | NVL | nuclear VCP like | ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); nucleotide binding (inferred); INVOLVED IN positive regulation of telomere maintenance (ortholog); FOUND IN nuclear exosome (RNase complex) (inferred); nucleolus (inferred); nucleoplasm (inferred); INTERACTS WITH bisphenol A | 7 | 40041692 | 40131984 | Dog | 31 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12528722 | Nvl | nuclear VCP like | ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); nucleotide binding (inferred); INVOLVED IN positive regulation of telomere maintenance (ortholog); FOUND IN nuclear exosome (RNase complex) (inferred); nucleolus (inferred); nucleoplasm (inferred) | NW_004936526 | 1274760 | 1381997 | Squirrel | 31 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18932736 | Nvl | nuclear VCP like | ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); nucleotide binding (inferred); INVOLVED IN positive regulation of telomere maintenance (ortholog); regulation of protein localization to nucleolus (ortholog); ribosomal large subunit biogenesis (ortholog); FO UND IN nuclear exosome (RNase complex) (ortholog); telomerase holoenzyme complex (ortholog) | | | | Naked Mole-Rat | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18512567 | NVL | nuclear VCP like | ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); nucleotide binding (inferred); INVOLVED IN positive regulation of telomere maintenance (ortholog); FOUND IN nuclear exosome (RNase complex) (inferred); nucleolus (inferred); nucleoplasm (inferred) | | | | Green Monkey | 32 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626034207 | Nvl | nuclear VCP like | ENCODES a protein that exhibits ATP binding (ortholog); preribosome binding (ortholog); INVOLVED IN positive regulation of telomere maintenance (ortholog); regulation of protein localization to nucleolus (ortholog); ribosomal large subunit biogenesis (ortholog); FOUND IN nuclear exosome (RNase compl ex) (ortholog); nucleolus (ortholog); nucleoplasm (ortholog) | | | | Black Rat | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155234821 | nvl | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 14286953 | NVL | nuclear VCP like | ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); nucleotide binding (inferred); INVOLVED IN positive regulation of telomere maintenance (ortholog); FOUND IN nuclear exosome (RNase complex) (inferred); nucleolus (inferred); nucleoplasm (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 31 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155234820 | nvl.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 708375 | Hpcal1 | hippocalcin-like 1 | ENCODES a protein that exhibits calcium ion binding (inferred); metal ion binding (inferred); INVOLVED IN liver development (ortholog); ASSOCIATED WITH cataract 13 with adult i phenotype (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN membrane (inferred); INTERACTS WITH 17beta-estradio l; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 6 | 46206809 | 46313364 | Rat | 161 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1551333 | Hpcal1 | hippocalcin-like 1 | Predicted to enable calcium ion binding activity. Acts upstream of or within liver development. Predicted to be located in membrane. Is expressed in several structures, including central nervous system; ganglia; and retina layer. Orthologous to human HPCAL1 (hippocalcin like 1). [provided by Allianc e of Genome Resources, Jul 2025] | 12 | 17740810 | 17841943 | Mouse | 168 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 708491 | Hpcal4 | hippocalcin-like 4 | ENCODES a protein that exhibits calcium channel regulator activity; protein domain specific binding; INVOLVED IN response to heat (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 5 | 140739577 | 140751529 | Rat | 92 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 3966 | Vsnl1 | visinin-like 1 | ENCODES a protein that exhibits calcium ion binding (inferred); metal ion binding (inferred); INVOLVED IN negative regulation of insulin secretion (ortholog); positive regulation of exocytosis (ortholog); positive regulation of insulin secretion involved in cellular response to glucose stimulus (ort holog); ASSOCIATED WITH Alzheimer's disease (ortholog); FOUND IN cytosol (ortholog); membrane (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 6 | 39757721 | 39878556 | Rat | 153 | old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1616814 | Vsnl1 | visinin-like 1 | Predicted to enable calcium ion binding activity. Acts upstream of or within negative regulation of insulin secretion; positive regulation of exocytosis; and positive regulation of insulin secretion involved in cellular response to glucose stimulus. Located in cytosol and membrane. Is expressed in s everal structures, including alimentary system; brain; great vessel of heart; heart; and sensory organ. Orthologous to human VSNL1 (visinin like 1). [provided by Alliance of Genome Resources, Jul 2025] | 12 | 11375258 | 11486579 | Mouse | 149 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |