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29 records found for search term Npr2
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
620851Npr2natriuretic peptide receptor 2ENCODES a protein that exhibits peptide hormone binding; guanylate cyclase activity (ortholog); hormone binding (ortholog); INVOLVED IN cGMP biosynthetic process; positive regulation of platelet-derived growth factor receptor signaling pathway; wound healing; PARTICIPATES IN C-type natriuretic pepti56267819762697360Rat321symbol , PhenoGengene, protein-coding, PROVISIONAL [RefSeq]
733765NPR2natriuretic peptide receptor 2This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly 93579159135809731Human515symbol , COSMIC , description , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
736630Npr2natriuretic peptide receptor 2Enables guanylate cyclase activity; identical protein binding activity; and natriuretic peptide receptor activity. Involved in several processes, including reproductive structure development; skeletal system development; and vasculature development. Acts upstream of or within bone development; negat44362901543651437Mouse410symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
8861347Npr2natriuretic peptide receptor 2ENCODES a protein that exhibits guanylate cyclase activity (ortholog); hormone binding (ortholog); identical protein binding (ortholog); INVOLVED IN activation of meiosis involved in egg activation (ortholog); axonogenesis (ortholog); axonogenesis involved in innervation (ortholog); PARTICIPATES IN NW_004955472506351523647Chinchilla121symbolgene, protein-coding, MODEL [RefSeq]
11871811NPR2natriuretic peptide receptor 2ENCODES a protein that exhibits peptide hormone binding (ortholog); INVOLVED IN bone development (ortholog); cGMP biosynthetic process (ortholog); negative regulation of meiotic cell cycle (ortholog); PARTICIPATES IN C-type natriuretic peptide signaling pathway; ASSOCIATED WITH achondroplasia (ortho93564253435660210Bonobo125symbolgene, protein-coding, MODEL [RefSeq]
12300727NPR2natriuretic peptide receptor 2ENCODES a protein that exhibits peptide hormone binding (ortholog); INVOLVED IN bone development (ortholog); cGMP biosynthetic process (ortholog); negative regulation of meiotic cell cycle (ortholog); PARTICIPATES IN C-type natriuretic peptide signaling pathway; ASSOCIATED WITH achondroplasia (ortho115228368052339247Dog118symbolgene, protein-coding, MODEL [RefSeq]
12466654Npr2natriuretic peptide receptor 2ENCODES a protein that exhibits peptide hormone binding (ortholog); INVOLVED IN bone development (ortholog); cGMP biosynthetic process (ortholog); negative regulation of meiotic cell cycle (ortholog); PARTICIPATES IN C-type natriuretic peptide signaling pathway; ASSOCIATED WITH achondroplasia (orthoNW_00493652437793983798074Squirrel122symbolgene, protein-coding, MODEL [RefSeq]
14213362NPR2natriuretic peptide receptor 2ENCODES a protein that exhibits peptide hormone binding (ortholog); INVOLVED IN bone development (ortholog); cGMP biosynthetic process (ortholog); negative regulation of meiotic cell cycle (ortholog); PARTICIPATES IN C-type natriuretic peptide signaling pathway; ASSOCIATED WITH achondroplasia (orthoPig120symbolgene, protein-coding, PROVISIONAL [RefSeq]
14381112NPR2Yeastsymbolgene, null
18523093NPR2natriuretic peptide receptor 2ENCODES a protein that exhibits peptide hormone binding (ortholog); INVOLVED IN bone development (ortholog); cGMP biosynthetic process (ortholog); negative regulation of meiotic cell cycle (ortholog); PARTICIPATES IN C-type natriuretic peptide signaling pathway; ASSOCIATED WITH achondroplasia (orthoGreen Monkey125symbolgene, protein-coding, MODEL [RefSeq]
18907643Npr2natriuretic peptide receptor 2ENCODES a protein that exhibits peptide hormone binding (ortholog); INVOLVED IN bone development (ortholog); cGMP biosynthetic process (ortholog); negative regulation of meiotic cell cycle (ortholog); PARTICIPATES IN C-type natriuretic peptide signaling pathway; ASSOCIATED WITH achondroplasia (orthoNaked Mole-Rat121symbolgene, protein-coding, MODEL [RefSeq]
285525971npr2Tropical Clawed Frogsymbolgene, null
626026058Npr2natriuretic peptide receptor 2ENCODES a protein that exhibits guanylate cyclase activity (ortholog); hormone binding (ortholog); identical protein binding (ortholog); INVOLVED IN activation of meiosis involved in egg activation (ortholog); axonogenesis (ortholog); axonogenesis involved in innervation (ortholog); PARTICIPATES IN Black Rat121symbolgene, protein-coding, MODEL [RefSeq]
288056923npr2.LAfrican Clawed Frogsymbolgene, null
284500766npr2.SAfrican Clawed Frogsymbolgene, null
1318978NPRL2NPR2 like, GATOR1 complex subunitEnables GTPase activator activity. Involved in cellular response to amino acid starvation; negative regulation of TORC1 signaling; and negative regulation of kinase activity. Part of GATOR1 complex. Is active in lysosomal membrane. Implicated in familial focal epilepsy with variable foci 2. [provide35034733050350775Human119old_gene_name , name , old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1308927Nprl2NPR2-like, GATOR1 complex subunitENCODES a protein that exhibits GTPase activator activity (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); negative regulation of kinase activity (ortholog); negative regulation of TORC1 signaling (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH epile8117094443117097639Rat78namegene, protein-coding, VALIDATED [RefSeq]
1318979Nprl2NPR2 like, GATOR1 complex subunitPredicted to contribute to GTPase activator activity. Involved in cellular response to amino acid starvation and negative regulation of TORC1 signaling. Predicted to be part of GATOR1 complex. Predicted to be active in lysosomal membrane. Is expressed in liver. Human ortholog(s) of this gene implica9107419405107422905Mouse98old_gene_name , name , description , old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
8742041Nprl2NPR2 like, GATOR1 complex subunitENCODES a protein that exhibits GTPase activator activity (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); negative regulation of kinase activity (ortholog); negative regulation of TORC1 signaling (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH epileNW_00495553221489502152671Chinchilla20old_gene_name , namegene, protein-coding, MODEL [RefSeq]
11816548NPRL2NPR2 like, GATOR1 complex subunitENCODES a protein that exhibits GTPase activator activity (inferred); INVOLVED IN negative regulation of kinase activity (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH epilepsy (ortholog); familial focal epilepsy with variable foci (ortholog); familial focal epilepsy with variab35027361150277175Bonobo24old_gene_name , namegene, protein-coding, MODEL [RefSeq]
12159047NPRL2NPR2 like, GATOR1 complex subunitENCODES a protein that exhibits GTPase activator activity (inferred); INVOLVED IN negative regulation of kinase activity (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH epilepsy (ortholog); familial focal epilepsy with variable foci (ortholog); familial focal epilepsy with variab203900569939009183Dog23old_gene_name , namegene, protein-coding, MODEL [RefSeq]
12626472Nprl2NPR2 like, GATOR1 complex subunitENCODES a protein that exhibits GTPase activator activity (inferred); INVOLVED IN negative regulation of kinase activity (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH epilepsy (ortholog); familial focal epilepsy with variable foci (ortholog); familial focal epilepsy with variabNW_00493953017455100Squirrel24old_gene_name , namegene, protein-coding, MODEL [RefSeq]
13863135NPRL2NPR2 like, GATOR1 complex subunitENCODES a protein that exhibits GTPase activator activity (inferred); INVOLVED IN negative regulation of kinase activity (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH epilepsy (ortholog); familial focal epilepsy with variable foci (ortholog); familial focal epilepsy with variabPig23namegene, protein-coding, MODEL [RefSeq]
18693636NPRL2NPR2 like, GATOR1 complex subunitENCODES a protein that exhibits GTPase activator activity (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); negative regulation of kinase activity (ortholog); negative regulation of TORC1 signaling (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH epileGreen Monkey20namegene, protein-coding, MODEL [RefSeq]
18936234Nprl2NPR2 like, GATOR1 complex subunitENCODES a protein that exhibits GTPase activator activity (inferred); INVOLVED IN negative regulation of kinase activity (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH epilepsy (ortholog); familial focal epilepsy with variable foci (ortholog); familial focal epilepsy with variabNaked Mole-Rat24namegene, protein-coding, MODEL [RefSeq]
20867051NPRL2NPR2 like, GATOR1 complex subunitENCODES a protein that exhibits GTPase activator activity (inferred); INVOLVED IN cellular response to amino acid starvation (inferred); negative regulation of TORC1 signaling (inferred); positive regulation of autophagy (inferred); FOUND IN GATOR1 complex (inferred); lysosomal membrane (inferred); Green Monkey12namegene, protein-coding
625845196Nprl2NPR2 like, GATOR1 complex subunitENCODES a protein that exhibits GTPase activator activity (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); negative regulation of kinase activity (ortholog); negative regulation of TORC1 signaling (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH epileBlack Rat20namegene, protein-coding, MODEL [RefSeq]
14197820TMEM115transmembrane protein 115ENCODES a protein that exhibits identical protein binding (inferred); INVOLVED IN retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum (inferred); FOUND IN Golgi apparatus (inferred); Golgi cisterna membrane (inferred); Golgi transport complex (inferred)Pig15ensembl_full_namegene, protein-coding, MODEL [RefSeq]
732882NPR1natriuretic peptide receptor 1Guanylyl cyclases, catalyzing the production of cGMP from GTP, are classified as soluble and membrane forms (Garbers and Lowe, 1994 [PubMed 7982997]). The membrane guanylyl cyclases, often termed guanylyl cyclases A through F, form a family of cell-surface receptors with a similar topographic struct1153678688153693992Human163descriptiongene, protein-coding, VALIDATED [RefSeq]