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Gene: Nprl2 (NPR2 like, GATOR1 complex subunit) Mus musculus
Symbol: Nprl2
Name: NPR2 like, GATOR1 complex subunit
Description: ENCODES a protein that exhibits GTPase activator activity (ortholog); protein kinase activity (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); negative regulation of kinase activity (ortholog); negative regulation of TOR signaling (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH abnormal amino acid metabolism; abnormal erythropoiesis; abnormal hematopoietic precursor cell number; ASSOCIATED WITH Familial Focal Epilepsy, with Variable Foci 1 (ortholog); Familial Focal Epilepsy, with Variable Foci 2 (ortholog); schizophrenia (ortholog); FOUND IN GATOR1 complex (ortholog); lysosomal membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-acetamidofluorene; bisphenol A
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2810446G01Rik; G21; GATOR complex protein NPRL2; gene 21 protein; nitrogen permase homolog; nitrogen permease regulator 2-like protein; nitrogen permease regulator-like 2; NPR2-like protein; NPR2L; tumor suppressor candidate 4; Tusc4
Homo sapiens (human) : NPRL2 (NPR2 like, GATOR1 complex subunit)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Nprl2 (NPR2-like, GATOR1 complex subunit)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nprl2 (NPR2 like, GATOR1 complex subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : NPRL2 (NPR2 like, GATOR1 complex subunit)
Canis lupus familiaris (dog) : NPRL2 (NPR2 like, GATOR1 complex subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nprl2 (NPR2 like, GATOR1 complex subunit)
Sus scrofa (pig) : NPRL2 (NPR2 like, GATOR1 complex subunit)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm389107,542,177 - 107,545,706 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv379107,444,540 - 107,448,037 (+)NCBIGRCm37mm9NCBIm37
MGSCv369107,400,327 - 107,403,796 (+)NCBImm8
Celera9107,150,974 - 107,154,469 (+)NCBICelera
Cytogenetic Map9 F1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Nprl2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1318979
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.