| 1307789 | Mri1 | methylthioribose-1-phosphate isomerase 1 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN amino acid biosynthetic process (inferred); L-methionine salvage from methylthioadenosine (inferred); methionine biosynthetic process (inferred); PARTICIPATES IN cysteine and methionine metabolic pathway; ASSOCIATED WI TH neurodegenerative disease (ortholog); FOUND IN nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; endosulfan; flutamide | 19 | 40812114 | 40819846 | Rat | 79 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1332408 | Mri1 | methylthioribose-1-phosphate isomerase 1 | Predicted to enable S-methyl-5-thioribose-1-phosphate isomerase activity and identical protein binding activity. Predicted to be involved in L-methionine salvage from methylthioadenosine. Predicted to be located in cytosol; fibrillar center; and nucleoplasm. Orthologous to human MRI1 ight:700;'>MRI1 (methylthioribose-1-phosphate isomerase 1). [provided by Alliance of Genome Resources, Jul 2025] | 8 | 84977205 | 84983953 | Mouse | 87 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1604271 | MRI1 | methylthioribose-1-phosphate isomerase 1 | This enzyme functions in the methionine salvage pathway by catalyzing the interconversion of methylthioribose-1-phosphate and methythioribulose-1-phosphate. Elevated expression of the encoded protein is associated with metastatic melanoma and this protein promotes melanoma cell invasion independent of its enzymatic activity. Mutations in this gene may be associated with vanishing white matter disease (VMWD). [provided by RefSeq, Jul 2016] | 19 | 13764522 | 13774282 | Human | 84 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 8866224 | Mri1 | methylthioribose-1-phosphate isomerase 1 | ENCODES a protein that exhibits identical protein binding (ortholog); ASSOCIATED WITH neurodegenerative disease (ortholog); FOUND IN nucleoplasm (ortholog) | NW_004955415 | 32585714 | 32589343 | Chinchilla | 5 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11985207 | MRI1 | methylthioribose-1-phosphate isomerase 1 | ENCODES a protein that exhibits identical protein binding (inferred); isomerase activity (inferred); S-methyl-5-thioribose-1-phosphate isomerase activity (inferred); INVOLVED IN amino acid biosynthetic process (inferred); L-methionine salvage from methylthioadenosine (inferred); methionine biosynthe tic process (inferred); ASSOCIATED WITH neurodegenerative disease (ortholog); FOUND IN cytoplasm (inferred); nucleoplasm (inferred); nucleus (inferred) | 19 | 13327569 | 13336286 | Bonobo | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12337881 | MRI1 | methylthioribose-1-phosphate isomerase 1 | ENCODES a protein that exhibits identical protein binding (inferred); isomerase activity (inferred); S-methyl-5-thioribose-1-phosphate isomerase activity (inferred); INVOLVED IN amino acid biosynthetic process (inferred); L-methionine salvage from methylthioadenosine (inferred); methionine biosynthe tic process (inferred); ASSOCIATED WITH neurodegenerative disease (ortholog); FOUND IN cytoplasm (inferred); nucleoplasm (inferred); nucleus (inferred) | 20 | 48648987 | 48658231 | Dog | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12696556 | Mri1 | methylthioribose-1-phosphate isomerase 1 | ENCODES a protein that exhibits identical protein binding (inferred); isomerase activity (inferred); S-methyl-5-thioribose-1-phosphate isomerase activity (inferred); INVOLVED IN amino acid biosynthetic process (inferred); L-methionine salvage from methylthioadenosine (inferred); methionine biosynthe tic process (inferred); ASSOCIATED WITH neurodegenerative disease (ortholog); FOUND IN cytoplasm (inferred); nucleoplasm (inferred); nucleus (inferred) | NW_004936659 | 2526274 | 2532878 | Squirrel | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13851760 | MRI1 | methylthioribose-1-phosphate isomerase 1 | ENCODES a protein that exhibits identical protein binding (inferred); isomerase activity (inferred); S-methyl-5-thioribose-1-phosphate isomerase activity (inferred); INVOLVED IN amino acid biosynthetic process (inferred); L-methionine salvage from methylthioadenosine (inferred); methionine biosynthe tic process (inferred); ASSOCIATED WITH neurodegenerative disease (ortholog); FOUND IN cytoplasm (inferred); nucleoplasm (inferred); nucleus (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18494517 | MRI1 | methylthioribose-1-phosphate isomerase 1 | ENCODES a protein that exhibits identical protein binding (inferred); isomerase activity (inferred); S-methyl-5-thioribose-1-phosphate isomerase activity (inferred); INVOLVED IN amino acid biosynthetic process (inferred); L-methionine salvage from methylthioadenosine (inferred); methionine biosynthe tic process (inferred); ASSOCIATED WITH neurodegenerative disease (ortholog); FOUND IN cytoplasm (inferred); nucleoplasm (inferred); nucleus (inferred) | | | | Green Monkey | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625967491 | Mri1 | methylthioribose-1-phosphate isomerase 1 | ENCODES a protein that exhibits identical protein binding (ortholog); ASSOCIATED WITH neurodegenerative disease (ortholog); FOUND IN nucleoplasm (ortholog) | | | | Black Rat | 5 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14372842 | MRI1 | | | | | | Yeast | | symbol | gene, null |
| 155252607 | mri1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18901974 | Mri1 | methylthioribose-1-phosphate isomerase 1 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN amino acid biosynthetic process (inferred); L-methionine salvage from methylthioadenosine (inferred); methionine biosynthetic process (inferred); ASSOCIATED WITH neurodegenerative disease (ortholog); FOUND IN nucleopla sm (ortholog) | | | | Naked Mole-Rat | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155253091 | mri1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 16564754 | AC008686.1 | novel transcript, antisense to MRI1 | | | | | Human | | name | gene, lncrna |
