| 3111 | Mras | muscle RAS oncogene homolog | ENCODES a protein that exhibits GTP-dependent protein binding (ortholog); GTPase activity (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); Ras protein signal transduction (ortholog); PARTICIPATES IN mitogen activated protein kinase signaling pathway; ASSOCIATED WIT H carotid artery disease (ortholog); coronary artery disease (ortholog); Coronary Disease (ortholog); FOUND IN cytoplasm (ortholog); protein phosphatase type 1 complex (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 8 | 108823374 | 108886104 | Rat | 140 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 10918 | Mras | muscle and microspikes RAS | Predicted to enable GTP-dependent protein binding activity; GTPase activity; and guanyl ribonucleotide binding activity. Acts upstream of or within cellular response to leukemia inhibitory factor. Predicted to be part of protein phosphatase type 1 complex. Predicted to be active in plasma membrane. Is expressed in several structures, including brain; branchial arch; future spinal cord; limb bud; and liver. Human ortholog(s) of this gene implicated in Noonan syndrome 11. Orthologous to human MRAS (muscle RAS oncogene homolog). [provided by Alliance of Genome Resources, Apr 2025] | 9 | 99267473 | 99319505 | Mouse | 153 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 733433 | MRAS | muscle RAS oncogene homolog | This gene encodes a member of the Ras family of small GTPases. These membrane-associated proteins function as signal transducers in multiple processes including cell growth and differentiation, and dysregulation of Ras signaling has been associated with many types of cancer. The encoded protein may play a role in the tumor necrosis factor-alpha and MAP kinase signaling pathways. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011] | 3 | 138347648 | 138405535 | Human | 287 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 8903339 | Mras | muscle RAS oncogene homolog | ENCODES a protein that exhibits GTP-dependent protein binding (ortholog); GTPase activity (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); Ras protein signal transduction (ortholog); ASSOCIATED WITH carotid artery disease (ortholog); coronary artery disease (orthol og); Coronary Disease (ortholog); FOUND IN cytoplasm (ortholog); protein phosphatase type 1 complex (ortholog) | NW_004955501 | 615303 | 670404 | Chinchilla | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11923581 | MRAS | muscle RAS oncogene homolog | ENCODES a protein that exhibits GTP binding (inferred); GTP-dependent protein binding (inferred); GTPase activity (inferred); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); ASSOCIATED WITH carotid artery disease (ortholog); coronary artery disease (ortholog); Coronary Diseas e (ortholog); FOUND IN cytoplasm (inferred); membrane (inferred); plasma membrane (inferred) | 3 | 135377488 | 135435338 | Bonobo | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12161722 | MRAS | muscle RAS oncogene homolog | ENCODES a protein that exhibits GTP binding (inferred); GTP-dependent protein binding (inferred); GTPase activity (inferred); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); ASSOCIATED WITH carotid artery disease (ortholog); coronary artery disease (ortholog); Coronary Diseas e (ortholog); FOUND IN cytoplasm (inferred); membrane (inferred); plasma membrane (inferred) | 23 | 34558278 | 34613987 | Dog | 30 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12689938 | Mras | muscle RAS oncogene homolog | ENCODES a protein that exhibits GTP binding (inferred); GTP-dependent protein binding (inferred); GTPase activity (inferred); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); ASSOCIATED WITH carotid artery disease (ortholog); coronary artery disease (ortholog); Coronary Diseas e (ortholog); FOUND IN cytoplasm (inferred); membrane (inferred); plasma membrane (inferred) | NW_004936540 | 672783 | 725129 | Squirrel | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626125092 | Mras | muscle RAS oncogene homolog | ENCODES a protein that exhibits GTP-dependent protein binding (ortholog); GTPase activity (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); Ras protein signal transduction (ortholog); ASSOCIATED WITH carotid artery disease (ortholog); coronary artery disease (orthol og); Coronary Disease (ortholog); FOUND IN cytoplasm (ortholog); protein phosphatase type 1 complex (ortholog) | | | | Black Rat | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18566608 | MRAS | muscle RAS oncogene homolog | ENCODES a protein that exhibits GTP binding (inferred); GTP-dependent protein binding (inferred); GTPase activity (inferred); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); ASSOCIATED WITH carotid artery disease (ortholog); coronary artery disease (ortholog); Coronary Diseas e (ortholog); FOUND IN cytoplasm (inferred); membrane (inferred); plasma membrane (inferred) | | | | Green Monkey | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18928868 | Mras | muscle RAS oncogene homolog | ENCODES a protein that exhibits GTP binding (inferred); GTP-dependent protein binding (inferred); GTPase activity (inferred); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); ASSOCIATED WITH carotid artery disease (ortholog); coronary artery disease (ortholog); Coronary Diseas e (ortholog); FOUND IN cytoplasm (inferred); endomembrane system (inferred); membrane (inferred) | | | | Naked Mole-Rat | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14091983 | MRAS | muscle RAS oncogene homolog | ENCODES a protein that exhibits GTP binding (inferred); GTP-dependent protein binding (inferred); GTPase activity (inferred); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); ASSOCIATED WITH carotid artery disease (ortholog); coronary artery disease (ortholog); Coronary Diseas e (ortholog); FOUND IN cytoplasm (inferred); membrane (inferred); plasma membrane (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 31 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155242967 | mras | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155234588 | mras.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155256503 | mras.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 16554160 | AC073143.1 | muscle RAS oncogene homolog (MRAS) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 1557976 | Rapgef5 | Rap guanine nucleotide exchange factor (GEF) 5 | Predicted to enable GTP-dependent protein binding activity and guanyl-nucleotide exchange factor activity. Predicted to be involved in Ras protein signal transduction. Predicted to be located in nuclear body. Predicted to be active in plasma membrane. Is expressed in several structures, including al imentary system; branchial arch; central nervous system; heart and pericardium; and sensory organ. Orthologous to human RAPGEF5 (Rap guanine nucleotide exchange factor 5). [provided by Alliance of Genome Resources, Jul 2025] | 12 | 117480146 | 117723472 | Mouse | 117 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1323477 | Rasal1 | RAS protein activator like 1 (GAP1 like) | Predicted to enable GTPase activator activity and zinc ion binding activity. Predicted to be involved in positive regulation of dendrite extension. Predicted to be located in cytosol. Predicted to colocalize with plasma membrane. Is expressed in telencephalon mantle layer. Orthologous to human RASAL 1 (RAS protein activator like 1). [provided by Alliance of Genome Resources, Apr 2025] | 5 | 120786105 | 120817662 | Mouse | 108 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |