| 1308937 | Mmp15 | matrix metallopeptidase 15 | ENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); metalloendopeptidase activity (inferred); INVOLVED IN response to estradiol; endodermal cell differentiation (ortholog); ASSOCIATED WITH Liver Reperfusion Injury; Developmental Disease (ortholog); Experiment al Liver Cirrhosis (ortholog); FOUND IN extracellular matrix (inferred); plasma membrane (inferred); INTERACTS WITH 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile; 1-naphthyl isothiocyanate; 17beta-estradiol | 19 | 9669506 | 9691000 | Rat | 146 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1318995 | MMP15 | matrix metallopeptidase 15 | This gene encodes a member of the peptidase M10 family and membrane-type subfamily of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Members of this subfamily contain a transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. The encoded preproprotein is proteolytically processed to generate the mature protease. This protein may play a role in cancer progression. [provided by RefSeq, Jan 2016] | 16 | 58025754 | 58046901 | Human | 154 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1318996 | Mmp15 | matrix metallopeptidase 15 | This gene encodes a member of the matrix metalloproteinase family of extracellular matrix-degrading enzymes that are involved in tissue remodeling, wound repair, progression of atherosclerosis and tumor invasion. The encoded preproprotein undergoes proteolytic processing to generate a mature, zinc-d ependent endopeptidase enzyme. A deficiency of the encoded protein in mice is compatible with normal development and postnatal growth. [provided by RefSeq, Feb 2016] | 8 | 96078924 | 96100921 | Mouse | 166 | symbol , PhenoGen | gene, protein-coding, REVIEWED [RefSeq] |
| 8802879 | Mmp15 | matrix metallopeptidase 15 | INVOLVED IN endodermal cell differentiation (ortholog); response to estradiol (ortholog); ASSOCIATED WITH Developmental Disease (ortholog); Experimental Liver Cirrhosis (ortholog); Experimental Mammary Neoplasms (ortholog) | NW_004955433 | 15584206 | 15603162 | Chinchilla | 10 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11886950 | MMP15 | matrix metallopeptidase 15 | ENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); metalloendopeptidase activity (inferred); INVOLVED IN response to estradiol (ortholog); ASSOCIATED WITH Developmental Disease (ortholog); Experimental Liver Cirrhosis (ortholog); Experimental Mammary Neoplas ms (ortholog); FOUND IN extracellular matrix (inferred); extracellular space (inferred); membrane (inferred) | 16 | 38304856 | 38326193 | Bonobo | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12339722 | MMP15 | matrix metallopeptidase 15 | ENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); metalloendopeptidase activity (inferred); INVOLVED IN response to estradiol (ortholog); ASSOCIATED WITH Developmental Disease (ortholog); Experimental Liver Cirrhosis (ortholog); Experimental Mammary Neoplas ms (ortholog); FOUND IN extracellular matrix (inferred); membrane (inferred) | 2 | 58501783 | 58512507 | Dog | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12490155 | Mmp15 | matrix metallopeptidase 15 | ENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); metalloendopeptidase activity (inferred); INVOLVED IN response to estradiol (ortholog); ASSOCIATED WITH Developmental Disease (ortholog); Experimental Liver Cirrhosis (ortholog); Experimental Mammary Neoplas ms (ortholog); FOUND IN extracellular matrix (inferred); extracellular space (inferred); membrane (inferred) | NW_004936475 | 9951876 | 9971631 | Squirrel | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13872060 | MMP15 | matrix metallopeptidase 15 | ENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); metalloendopeptidase activity (inferred); INVOLVED IN response to estradiol (ortholog); ASSOCIATED WITH Developmental Disease (ortholog); Experimental Liver Cirrhosis (ortholog); Experimental Mammary Neoplas ms (ortholog); FOUND IN extracellular matrix (inferred); membrane (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18429633 | MMP15 | matrix metallopeptidase 15 | ENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); metalloendopeptidase activity (inferred); INVOLVED IN response to estradiol (ortholog); ASSOCIATED WITH Developmental Disease (ortholog); Experimental Liver Cirrhosis (ortholog); Experimental Mammary Neoplas ms (ortholog); FOUND IN extracellular matrix (inferred); extracellular space (inferred); membrane (inferred) | | | | Green Monkey | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155233532 | mmp15 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18928794 | Mmp15 | matrix metallopeptidase 15 | ENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); metalloendopeptidase activity (inferred); INVOLVED IN endodermal cell differentiation (ortholog); response to estradiol (ortholog); ASSOCIATED WITH Developmental Disease (ortholog); Experimental Liver Cirrho sis (ortholog); Experimental Mammary Neoplasms (ortholog); FOUND IN extracellular matrix (inferred); extracellular space (inferred); membrane (inferred) | | | | Naked Mole-Rat | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625957116 | Mmp15 | matrix metallopeptidase 15 | INVOLVED IN endodermal cell differentiation (ortholog); response to estradiol (ortholog); ASSOCIATED WITH Developmental Disease (ortholog); Experimental Liver Cirrhosis (ortholog); Experimental Mammary Neoplasms (ortholog) | | | | Black Rat | 10 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155232775 | mmp15.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155233533 | mmp15.S | | | | | | African Clawed Frog | | symbol | gene, null |