| 620327 | Manea | mannosidase, endo-alpha | ENCODES a protein that exhibits alpha-mannosidase activity; glycoprotein endo-alpha-1,2-mannosidase activity (ortholog); ASSOCIATED WITH anxiety disorder (ortholog); cocaine dependence (ortholog); Cocaine-Related Disorders (ortholog); FOUND IN Golgi apparatus (ortholog); Golgi membrane (ortholog); I NTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; ammonium chloride | 5 | 44992937 | 45015084 | Rat | 103 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1345544 | MANEA | mannosidase endo-alpha | N-glycosylation of proteins is initiated in the endoplasmic reticulum (ER) by the transfer of the preassembled oligosaccharide glucose-3-mannose-9-N-acetylglucosamine-2 from dolichyl pyrophosphate to acceptor sites on the target protein by an oligosaccharyltransferase complex. This core oligosacchar ide is sequentially processed by several ER glycosidases and by an endomannosidase (E.C. 3.2.1.130), such as MANEA, in the Golgi. MANEA catalyzes the release of mono-, di-, and triglucosylmannose oligosaccharides by cleaving the alpha-1,2-mannosidic bond that links them to high-mannose glycans (Hamilton et al., 2005 [PubMed 15677381]).[supplied by OMIM, Sep 2008] | 6 | 95577535 | 95609452 | Human | 109 | symbol , COSMIC , description , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1619809 | Manea | mannosidase, endo-alpha | Predicted to enable glycoprotein endo-alpha-1,2-mannosidase activity. Predicted to be located in Golgi apparatus. Predicted to be active in Golgi membrane. Human ortholog(s) of this gene implicated in anxiety disorder; cocaine dependence; and panic disorder. Orthologous to human MANEA ight:700;'>MANEA (mannosidase endo-alpha). [provided by Alliance of Genome Resources, Jul 2025] | 4 | 26324506 | 26346913 | Mouse | 105 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 9005616 | Manea | mannosidase endo-alpha | ENCODES a protein that exhibits alpha-mannosidase activity (ortholog); glycoprotein endo-alpha-1,2-mannosidase activity (ortholog); ASSOCIATED WITH anxiety disorder (ortholog); cocaine dependence (ortholog); Cocaine-Related Disorders (ortholog); FOUND IN Golgi apparatus (ortholog); Golgi membrane (o rtholog) | NW_004955411 | 21729085 | 21763684 | Chinchilla | 12 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11909900 | MANEA | mannosidase endo-alpha | ENCODES a protein that exhibits alpha-mannosidase activity (ortholog); ASSOCIATED WITH anxiety disorder (ortholog); cocaine dependence (ortholog); Cocaine-Related Disorders (ortholog); FOUND IN Golgi apparatus (inferred); Golgi membrane (inferred) | 6 | 93428813 | 93460576 | Bonobo | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12300183 | MANEA | mannosidase endo-alpha | ENCODES a protein that exhibits alpha-mannosidase activity (ortholog); ASSOCIATED WITH anxiety disorder (ortholog); cocaine dependence (ortholog); Cocaine-Related Disorders (ortholog); FOUND IN Golgi apparatus (inferred); Golgi membrane (inferred) | 12 | 54156398 | 54229183 | Dog | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12669205 | Manea | mannosidase endo-alpha | ENCODES a protein that exhibits alpha-mannosidase activity (ortholog); ASSOCIATED WITH anxiety disorder (ortholog); cocaine dependence (ortholog); Cocaine-Related Disorders (ortholog); FOUND IN Golgi apparatus (inferred); Golgi membrane (inferred) | NW_004936699 | 1975391 | 2006816 | Squirrel | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13882228 | MANEA | mannosidase endo-alpha | ENCODES a protein that exhibits alpha-mannosidase activity (ortholog); ASSOCIATED WITH anxiety disorder (ortholog); cocaine dependence (ortholog); Cocaine-Related Disorders (ortholog); FOUND IN Golgi apparatus (inferred); Golgi membrane (inferred) | | | | Pig | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18602487 | MANEA | mannosidase endo-alpha | ENCODES a protein that exhibits alpha-mannosidase activity (ortholog); ASSOCIATED WITH anxiety disorder (ortholog); cocaine dependence (ortholog); Cocaine-Related Disorders (ortholog); FOUND IN Golgi apparatus (inferred); Golgi membrane (inferred) | | | | Green Monkey | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18932228 | Manea | mannosidase endo-alpha | ENCODES a protein that exhibits alpha-mannosidase activity (ortholog); ASSOCIATED WITH anxiety disorder (ortholog); cocaine dependence (ortholog); Cocaine-Related Disorders (ortholog); FOUND IN Golgi apparatus (ortholog); Golgi membrane (ortholog) | | | | Naked Mole-Rat | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155234010 | manea | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626077179 | Manea | mannosidase endo-alpha | ENCODES a protein that exhibits alpha-mannosidase activity (ortholog); glycoprotein endo-alpha-1,2-mannosidase activity (ortholog); ASSOCIATED WITH anxiety disorder (ortholog); cocaine dependence (ortholog); Cocaine-Related Disorders (ortholog); FOUND IN Golgi apparatus (ortholog); Golgi membrane (o rtholog) | | | | Black Rat | 12 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155250308 | manea.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 5687775 | MANEA-DT | MANEA divergent transcript | INTERACTS WITH benzo[a]pyrene; cadmium dichloride; lipopolysaccharide | 6 | 95560096 | 95577451 | Human | 7 | symbol , old_gene_name , COSMIC , name , Human Proteome Map , old_gene_symbol | gene, ncrna, VALIDATED [RefSeq] |
| 1563973 | Maneal | mannosidase, endo-alpha-like | ENCODES a protein that exhibits hydrolase activity (inferred); hydrolase activity, acting on glycosyl bonds (inferred); FOUND IN Golgi membrane (inferred); INTERACTS WITH bisphenol A; 1,2-dichloroethane (ortholog); 17beta-estradiol (ortholog) | 5 | 142399816 | 142406960 | Rat | 47 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1604520 | MANEAL | mannosidase endo-alpha like | Predicted to enable alpha-mannosidase activity. Predicted to be located in Golgi membrane. [provided by Alliance of Genome Resources, Jul 2025] | 1 | 37793847 | 37801133 | Human | 48 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1619871 | Maneal | mannosidase, endo-alpha-like | Predicted to enable alpha-mannosidase activity. Predicted to be located in Golgi membrane. Orthologous to human MANEAL (mannosidase endo-alpha like). [provided by Alliance of Genome Resources, Jul 2025] | 4 | 124749032 | 124774731 | Mouse | 51 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 9035366 | Maneal | mannosidase endo-alpha like | | NW_004955452 | 15569603 | 15574744 | Chinchilla | | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11851916 | MANEAL | mannosidase endo-alpha like | ENCODES a protein that exhibits alpha-mannosidase activity (inferred); hydrolase activity (inferred); hydrolase activity, acting on glycosyl bonds (inferred); FOUND IN Golgi membrane (inferred) | 1 | 37068591 | 37075844 | Bonobo | 4 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12116461 | MANEAL | mannosidase endo-alpha like | ENCODES a protein that exhibits alpha-mannosidase activity (inferred); hydrolase activity (inferred); hydrolase activity, acting on glycosyl bonds (inferred); FOUND IN Golgi membrane (inferred) | 15 | 4729209 | 4733832 | Dog | 5 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12731948 | Maneal | mannosidase endo-alpha like | ENCODES a protein that exhibits alpha-mannosidase activity (inferred); hydrolase activity (inferred); hydrolase activity, acting on glycosyl bonds (inferred); FOUND IN Golgi membrane (inferred) | NW_004936474 | 19971351 | 19975294 | Squirrel | 5 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13846772 | MANEAL | mannosidase endo-alpha like | ENCODES a protein that exhibits alpha-mannosidase activity (inferred); hydrolase activity (inferred); hydrolase activity, acting on glycosyl bonds (inferred); FOUND IN Golgi membrane (inferred) | | | | Pig | 5 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18655351 | MANEAL | mannosidase endo-alpha like | ENCODES a protein that exhibits alpha-mannosidase activity (inferred); hydrolase activity (inferred); hydrolase activity, acting on glycosyl bonds (inferred); FOUND IN Golgi membrane (inferred) | | | | Green Monkey | 5 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18901820 | Maneal | mannosidase endo-alpha like | ENCODES a protein that exhibits alpha-mannosidase activity (inferred); hydrolase activity (inferred); hydrolase activity, acting on glycosyl bonds (inferred); FOUND IN Golgi membrane (inferred) | | | | Naked Mole-Rat | 5 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 39131464 | MANEAL | mannosidase endo-alpha like | | | | | Chinchilla | | symbol | gene, protein-coding |
| 155242634 | maneal | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626119936 | Maneal | mannosidase endo-alpha like | | | | | Black Rat | | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155256814 | maneal.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155242635 | maneal.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 14995994 | MANEALP1 | MANEAL pseudogene 1 | | 2 | 135897813 | 135898972 | Human | | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |