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Gene: Maneal (mannosidase endo-alpha like) Ictidomys tridecemlineatus

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Symbol:

Maneal

Name:

mannosidase endo-alpha like

RGD ID:

12731948

Description:

ENCODES a protein that exhibits alpha-mannosidase activity (inferred); hydrolase activity, acting on glycosyl bonds (inferred); ASSOCIATED WITH Charcot-Marie-Tooth disease dominant intermediate C (ortholog); FOUND IN Golgi apparatus (inferred); Golgi membrane (inferred); membrane (inferred)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	54,146,569 - 54,150,523 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936474	19,969,868 - 19,974,204 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936474	19,971,351 - 19,975,294 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Charcot-Marie-Tooth disease dominant intermediate C (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

Golgi apparatus (IEA)

Golgi membrane (IEA)

membrane (IEA)

Molecular Function

alpha-mannosidase activity (IEA)

hydrolase activity, acting on glycosyl bonds (IEA)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Maneal
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	54,146,569 - 54,150,523 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936474	19,969,868 - 19,974,204 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936474	19,971,351 - 19,975,294 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MANEAL
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	37,793,847 - 37,801,133 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	37,793,847 - 37,801,137 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	38,259,519 - 38,266,805 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	38,032,361 - 38,039,807 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	1	36,537,598 - 36,545,102 (+)	NCBI		Celera
Cytogenetic Map	1	p34.3	NCBI
HuRef	1	36,378,574 - 36,385,560 (+)	NCBI		HuRef
CHM1_1	1	38,375,603 - 38,383,106 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	37,660,740 - 37,668,025 (+)	NCBI		T2T-CHM13v2.0

Maneal
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	124,749,032 - 124,774,731 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	124,749,032 - 124,755,964 (-)	Ensembl		GRCm39 Ensembl
GRCm38	4	124,855,239 - 124,880,938 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	124,855,239 - 124,862,171 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	124,532,483 - 124,539,415 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	124,357,543 - 124,364,475 (-)	NCBI		MGSCv36	mm8
Celera	4	123,176,581 - 123,184,107 (-)	NCBI		Celera
Cytogenetic Map	4	D2.2	NCBI
cM Map	4	57.92	NCBI

Maneal
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	142,399,816 - 142,406,960 (-)	NCBI		GRCr8
mRatBN7.2	5	137,115,154 - 137,122,299 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	137,115,632 - 137,122,353 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	5	142,850,139 - 142,857,292 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	142,851,526 - 142,857,131 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	146,620,783 - 146,627,907 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	144,189,834 - 144,196,136 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	5	135,637,897 - 135,645,055 (-)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

Maneal
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955452	15,569,603 - 15,574,744 (+)	NCBI	ChiLan1.0	ChiLan1.0

MANEAL
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	189,036,404 - 189,043,694 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	188,165,543 - 188,172,828 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	37,068,591 - 37,075,844 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	38,417,575 - 38,424,275 (+)	NCBI	panpan1.1	PanPan1.1	panPan2

MANEAL
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	15	4,729,209 - 4,733,832 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	15	4,730,355 - 4,734,568 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	15	4,971,398 - 4,976,744 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	15	4,858,045 - 4,863,394 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	15	4,857,233 - 4,863,726 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	15	4,717,833 - 4,723,177 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	15	4,784,364 - 4,789,696 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	15	4,800,695 - 4,806,042 (-)	NCBI		UU_Cfam_GSD_1.0

MANEAL
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	93,821,535 - 93,829,456 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	93,821,638 - 93,832,122 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

MANEAL
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	95,061,150 - 95,067,929 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	95,062,080 - 95,067,846 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666033	21,742,544 - 21,749,935 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Maneal
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624764	20,497,556 - 20,503,057 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624764	20,497,517 - 20,504,113 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_013363918	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000117	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSTOT00000001634 ⟹ ENSSTOP00000001464

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936474	19,969,868 - 19,974,204 (+)	Ensembl

RefSeq Acc Id:

XM_013363918 ⟹ XP_013219372

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405058	54,146,569 - 54,150,523 (+)	NCBI
SpeTri2.0	NW_004936474	19,971,351 - 19,975,294 (+)	NCBI

Sequence:

show sequence

ATGATAACGGGGAACCCTCAGATGATCTTGTACCTGCTATTCTGGATACAGCCCACCAGTACAA
CATCCAGATATGGATCCCATGGTGCGTTTTACCGCTATAAGAACAGCATTGGCAAGAGCCTCCC
ACTCTTTTATATCTACGACTCATACCTAACATCCCCTGAAGCCTGGGCCCACCTCCTGACACCC
AATGGGCCCCACTCAATCCGCAACACTCTCTATGATGGGGTCTTCATAGCACTACTGGTGGAGG
AGGGTCATACCCATGACATCCTTGCTGCAGGATTTGATGGCATGTACACCTACTTTGCCTCCAA
TGGTTTCTCCTTCGGCTCCTCCCACCAGAACTGGAAAGCTGTTAAGAACTTTTGTGACGCCAAC
AACCTCATGTTCATTCCAAGTGTGGGGCCTGGCTACATTGACACTAGCATTCGACCCTGGAACA
ACCACAATACTCGGAACAGGGTCAATGGCAAGTATTATGAGACAGCCCTGCAAGCAGCCCTGAC
CGTGAGGCCTGAGATCGTTTCCATCACCTCTTTCAATGAGTGGCACGAAGGTACCCAGATCGAG
AAGGCCATTCCCAAGAAGACACCAACACGCTTGTATCTGGACTACCTGCCTCATCAGCCCAGTC
TGTACCTAGAGCTGACCCGCCGCTGGGCAGAGCATTTCATAAAGGAGAAGGAGCAGTGGCTGAT
GTGAGGGGCCCATGAACAAGGGCATGAGGTGTGCTGGCTCAGCTGAGGCTGTAGGTACTCAATG
GTCCCCAAGTGAGCAGCTGAGTGCTTCTGGGTGGGCCATGAAGCCAGGGCCCCTATAGAAGAGT
CTATTCCTCAGGTAAGCAGTGCTGGGGTAACCTGTGATGCAAAGTGAGGTGGTGTACCCAAGGG
AAGAGTAGAGGCTGGCAGGTGACTTTTACTTAGCCCAGGCAGCTCCACATCCTCCTCAGAACAC
TTTCATACAACCTCTGCTGCAAGTGGTGGTTGTCTTGTGGAGTCACCCGACCACTGCTCTTGGA
AAGTTTTCAGGATTCTGAACTAGTATGCACCCTGCTCCTTTCTGCCAGCCTCCCCACAACATTG
TCTTCTTGGAAGACAAGCAACCACTTCTAAGACTTTTTAGAAGGAAACTTTCTAAAAGGAAGCT
CCTCCCAGTAGATTCCTGAACCCAATTACCAGGAAGTCATCTTGAACATTCACACATTTATTCA
ACACTCACAAACTGAGCACCTTACTATGTGCTAGGTGCTGGGGAAAACTTGACTGAGGAATGGC
TCCTGTCCTTCTGAAACTTACAGGAATCAGCCTTCCTTACTTGGTGTGGCCTTGTCGCTAGTGC
TTGGGCACAGTTTTAAGTTTTGTGTTTTTTTTTTTGGCAATTGTACCCAGTGCTGAGAGTTCAG
TTCCTTTTCCTCGAAGAAAATACCTCTGTGCTCCAGAACCTACTTTCTCTGGGATGAACTTTCA
GTTCCAGGCAGAGTAGTAGGATACCTTTTCCCTTTAGCTGCCCAAACTGAACAGGGCCCACTTG
TCAGAACCGCTTTCAGTGCTACTGTGATTTTTACTAATGAAGTATCAAGCAGTATTCTCAAGTC
CACACTCCTTTTGCCCCCAAGACCTGTTTCTGACCTGAGTCAGATTCTGGGACAAAATGATATA
TGGGTTGGGCTGGCTATAGTTTTAGCACAATGAAGAGTGGGTTTGCTTAATAAGTTACTGGTTT
ACCTAAGATTTCTAGAGGGAATAGTTAACAAACCAGTGTTTATCTATGAATAAATTGCATTAAA
ACAGGA

hide sequence

Protein Sequences


Protein RefSeqs	XP_013219372	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000001464.2
GenBank Protein	KAG3282780	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_013219372 ⟸ XM_013363918

- Sequence:

show sequence

MITGNPQMILYLLFWIQPTSTTSRYGSHGAFYRYKNSIGKSLPLFYIYDSYLTSPEAWAHLLTP
NGPHSIRNTLYDGVFIALLVEEGHTHDILAAGFDGMYTYFASNGFSFGSSHQNWKAVKNFCDAN
NLMFIPSVGPGYIDTSIRPWNNHNTRNRVNGKYYETALQAALTVRPEIVSITSFNEWHEGTQIE
KAIPKKTPTRLYLDYLPHQPSLYLELTRRWAEHFIKEKEQWLM

hide sequence

Ensembl Acc Id:

ENSSTOP00000001464 ⟸ ENSSTOT00000001634

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000001640	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000001634.2	UniProtKB/TrEMBL
Gene3D-CATH	Glycosidases	UniProtKB/TrEMBL
InterPro	Glyco_Hydrolase_99	UniProtKB/TrEMBL
NCBI Gene	Maneal	ENTREZGENE
PANTHER	GLYCOPROTEIN ENDO-ALPHA-1,2-MANNOSIDASE-LIKE PROTEIN	UniProtKB/TrEMBL
	PTHR13572	UniProtKB/TrEMBL
Pfam	Glyco_hydro_99	UniProtKB/TrEMBL
UniProt	I3LYY5_ICTTR	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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